@article{MILIADIS_MALATOU_TSIANTAS_VRETTAKOU_EVANGELOU_ANAGNOSTOPOULOS_SIRAGAKIS_2018, title={Carry over effect in pesticide residues analysis by LC - MS/ MS}, volume={68}, url={https://ejournals.epublishing.ekt.gr/index.php/jhvms/article/view/16059}, DOI={10.12681/jhvms.16059}, abstractNote={<p><span lang="EN-US">The Carry over effect, i.e. the appearance of a peak in the chromatogram of a blank analysis due to sample remaining from the previous analysis, was studied. The study was conducted for pesticide residues analysis by LC-MS/MS. In total 128 pesticides that belong to 13 different chemical classes were analyzed in order to investigate the cases that the effect is significant; i.e. a peak higher than 1% of the peak of the previous chromatogram appears. Carry over was found for 32 of the 128 studied pesticides (25%), at concentration levels between the LOD and 0.167 </span><span>μ</span><span lang="EN-US">g/mL. </span><span lang="EN-US">For 28 out of the 32 substances, more than two injections of a blank sample were required, as to reduce the effect significantly. Compounds presenting Carry over effect were mainly non-polar with logkow values between 4 and 7, char</span><span lang="EN-US">acterized with very low water solubility, between 0.001 mg/L and 2 mg/L. On the contrary, the vapor pressure did not seem to be obviously related to the effect, as the substances presenting Carry over had various vapor pressure values, from 10-12 to 0.2 mP.</span></p>}, number={4}, journal={Journal of the Hellenic Veterinary Medical Society}, author={MILIADIS, G. and MALATOU, P. and TSIANTAS, P. and VRETTAKOU, A. and EVANGELOU, V. I. and ANAGNOSTOPOULOS, Ch. and SIRAGAKIS, G.}, year={2018}, month={Mar.}, pages={607–612} }