@article{Bayraktar_Özdemir_2022, title={A meta-analysis of the association between Growth Hormone (GH) gene polymorphism and growth traits in cattle breeds}, volume={73}, url={https://ejournals.epublishing.ekt.gr/index.php/jhvms/article/view/29407}, DOI={10.12681/jhvms.29407}, abstractNote={<p>GH gene is one of the important genes that affect the productive and physiological traits in livestock. This study aimed to use a meta-analysis to determine the association of the GH gene with growth traits in cattle. Four different genetic models were used: dominant LL + LV versus VV, recessive LL versus LV + VV, complete over dominant LL+VV vs. LV and co-dominant LL vs. LV, LL vs. VV and LV vs. VV. The random-effect model was used in data analysis based on <em>I<sup>2</sup></em>. Meta-analysis showed an effect of GH genotypes on the birth weight (BW) under the recessive (p<0.05) and complete over dominant (p<0.01) models. However, no association (p>0.05) was found under the dominant model. In terms of co-dominant model, the GH polymorphism showed a significant association with BW (SMD = 0.359, 95% CI = 0.119 to 0.599, p = 0.003) under LL vs. LV genotype combination patterns. No association was found between GH polymorphism and BW under LL vs. VV genotype combination. The results showed that the LL genotype had a significant effect on BW traits from LV and VV genotypes when comparing the models. The results showed an effect of the GH on ADG under four genetic models (p<0.05).</p>}, number={3}, journal={Journal of the Hellenic Veterinary Medical Society}, author={Bayraktar, M and Özdemir, M}, year={2022}, month={Nov.}, pages={4657–4666} }