GISSI, CARMELA, CoNISMa, Piazzale Flaminio 9, 00197, Roma, Italy & Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari Aldo Moro, Via Orabona 4, 70125 Bari, Italy & Institute of Biomembranes, Bioenergetics and Molecular Biotechnologies (IBIOM), CNR, Via Amendola 165/A - 70126 Bari, Italy, Italy