Recommendations for the safe transport and delivery of laboratory animals to research centres

Published: Nov 27, 2017
laboratory animals transport delivery

This paper reviews the current requirements for the transport and delivery of laboratory animals to research centres, in order to achieve an optimum level of their health and welfare. Transport conditions, delivery and reception of animals at the facility, their clinical examination by a veterinarian and management during the acclimatization period are considered to be of maximum importance for the preservation of their health and welfare status, as well as for the validity of experimental results. The current existing legislation and the recommendations issued by European and international organizations are presented, taking into account the fact that they are under continuous update according to new scientific evidence.

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Aguila ΗΝ, Pakes SP, Lai WC, Lu YS (1988) The effect of transportation stress on splenic natural killer cell activity in C57BL/6J mice. Lab Anim Sci, 38: 148-151
Anonymous (1992a) Handling and sexing. In: The Principles of Animal Technology I. Edited by Kelly Ρ J, Millican KG, Organ PJ. The Institute of Animal Technology, UK : A1-A17
Anonymous (1992b) Animal Health. In: The Principles of Animal Technology I. Edited by Kelly PJ, Millican KG, Organ PJ. The Institute of Animal Technology, UK : C1-C7
Anonymous In:
Anonymous In:
Anonymous In:
Dalin AM, Magnusson U, Haggendal J, Nyberg L (1993) The effect of transport stress on plasma levels of catecholamines, Cortisol, corticosterone-binding globulin, blood cell count and lymphocyte proliferation in pigs. Acta Veterinaria Scandinavica, 34: 59-68
LABA/LASA Working Group Report in association with the ABPI, IAT, UFAW and Animals (Scientific Procedures)
Inspectorate (1993) Guidelines for the care of Lab Anim in transit. Lab Anim, 27: 93-107
Lipman NS, Corning BF, Coirò MA (1992) The effects of intracage ventilation on microenvironmental conditions in filter-top cages. Lab Anim, 26: 206-210
Mäher JA and Schub Τ (2004) Laboratory Rodent Transportation Supplies. Lab Anim Europe, 4 (8): 22-25
Nicklas W, Baneux P, Boot R, Decelle Τ, Deeny AA, Fumanelli M, Illgen-Wilcke Β (2002) Recommendations for the health monitoring of rodent and rabbit colonies in breeding and experimental units. Lab Anim, 36: 20-42
Οδηγία 86/609/EOK του Συμβουλίου «για την προσέγγιση των νομοθετικών, κανονιστικών και διοικητικών διατάξεων των κρατών-μελών σχετικά με την προστασία των ζώων που χρησιμοποιούνται για πειραματικούς και άλλους επιστημονικούς σκοπούς"
(L 358)
Orcutt RP, Phelan RS, Geisstfeid JG (2001) Exclusion of mouse hepatitis virus from a filtered, plastic rodent shipping container during an in-transit field challenge. Contemp Top Lab Anim Sci, 40(4):32-35
ΠΔ 160/1991 (A 64) «Προστασία των ζώων που χρησιμοποιούνται για πειραματικούς και άλλους επιστημονικούς σκοπούς, σε συμμόρφωση προς την Οδηγία 86/609/ΕΟΚ του Συμβουλίου»
ΠΔ 344/1997 (Α 233) «Προστασία των ζώων κατά τη μεταφορά σε συμμόρφωση προς τις Οδηγίες 91/628/ΕΟΚ και 95/29/ΕΚ του Συμβουλίου»
Rehbinder C, Baneux Ρ, Forbes D, van Herck Η, Nicklas W, Rugaya Z, Winkler G (1998) FELASA recommendations for the health monitoring of breeding colonies and experimental units of cats, dogs and pigs. Lab Anim, 32: 1-17
Rehg JE and Toth LA (1998) Rodent quarantine programs: purpose, principles and practice. Lab Anim Sci, 48 (5): 438-47
SCAHAW (2002) The Welfare of Animals during Transport (details for horses, pigs, sheep and cattle). Health and Consumer Protection Directorate-General, European Commission,
Swallow J, Anderson D, Buckwell AC, Harris T, Hawkins P, Kirkwood J, Lomas M, Meacham S, Peters A, Prescott M, Owen S, Quest R, Sutcliffe R, Thompson Κ (2005) Guidance on the transport of Laboratory Animals. Lab Anim, 39:1-39
Swindle MM (1998) Biology, Husbandry, Handling and Anatomy. In: Surgery, Anaesthesia and Experimental Techniques in Swine. Iowa State University Press: 3-32
Tabata H, Kitamura T, Nagamatsu Ν (1998) Comparison of effects of restraint, cage transportation, anaesthesia and repeated bleeding on plasma glucose levels between mice and rats. Lab Anim, 32: 143-8
Tuli JS, Smith JA, Morton DB (1995) Stress measurements after transportation. Lab Anim, 29:132-138
van Ruiven R, Meijer GW, Wiersma A, Baumans V, van Zutphen LFM, Ritskes-Hoitinga J (1998) The influence of transportation stress on selected nutritional parameters to establish the necessary minimum period for adaptation in rat feeding studies. Lab Anim, 32: 446-456
Working Party for the Preparation of the Multilateral Consultation of parties to the European Convention for the protection of animals during International Transport (ETS 65). Draft Code of conduct for the international transport of animals by road, http ://xtraO 1 .legalcoop. eoe. int/T/3_Biological_safety_use_of_ani mals/Home