Ovine small bowel “minute rhythm” intensity related to feeding and phase of migrating myoelectric complex

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Published: Jan 29, 2018
DOI: https://doi.org/10.12681/jhvms.15525
Keywords:
ram duodenum jejunum electromyography motility patterns
K. W. ROMAŃSKI
Department of Biostructure and Animal Physiology, Faculty of Veterinary Medicine, Wroclaw University of Environmental and Life Sciences
Abstract

The presented study was performed to characterize further the ‘minute rhythm’ in the ovine small bowel, notably to assess the role of fasting and feeding as well as of the phase of the MMC upon the number and amplitude of the MR-containing spike bursts. In eight rams the electrodes were attached to the pyloric antrum, duodenal bulb, duodenum and upper jejunum. In the course of chronic experiments, the myoelectrical recordings were conducted in fasted and non-fasted rams, before and after feeding offered during phase 2a or 2b of the MMC. The phases of the MMC and the MR episodes were identified and the MR frequency, the number of the spike bursts in one MR episode and their amplitudes were calculated. 74 per cent of the MR episodes exhibited the propagated character. At the beginning of phase 2a, the MR often arrived exclusively in the duodenal bulb and was disorganized, while at the end of phase 2b of the MMC, the MR-related spike bursts were most prominent and propulsive. In the duodenal bulb, the giant-like spike bursts forming the pattern were observed occasionally. The MR episodes contained usually 1-2 spike bursts. The number of the MR episodes, each containing one spike burst was smaller after feeding mostly in the duodenum and jejunum and it was lower during phase 2b than during phase 2a of the MMC in the duodenal bulb, duodenum and jejunum. The number of the spike bursts in one MR episode increased after feeding and during phase 2b of the migrating myoelectric complex and it was the highest in the jejunum. The spike burst amplitudes of the MR episodes were the highest in the duodenal bulb. Feeding during phase 2b of the MMC decreased the amplitude of the MR-related spike bursts both in the duodenum and the jejunum. It is concluded that the intensity of the MR in the ovine small bowel is related to feeding and to the phase of the MMC and the high variability of the pattern comprises its character and strength that are apparently related to the intraluminal influences affecting the controlling mechanisms.

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References
Ahluwalia NK, Thompson DG, Barlow J, Heggie L (1994) Human small intestinal contractions and aboral traction forces during fasting andafter feeding. Gut 35: 625-630.
Andrews JM, Doran SM, Hebbard GS, Malbert CH, Horowitz M, Dent J (2001) Nutrient-induced spatial patterning of human duodenal motor function. Am J Physiol 280: G501-G509.
Behrns KE, Sarr MG (1994) Duodenal nutrients inhibit canine jejuna fasting motor patterns through a hormonal mechanism. Dig Dis Sci 39: 1665-1671.
Bueno L, Fioramonti J (1980) Rhythms of abomaso-intestinal motility. In: Digestive Physiology and Metabolism in Ruminants. Ruckebusch Y, Thivend P (eds), MTP Press Limited, Lancaster: pp 53-80.
Bueno L, Fioramonti J, Ruckebusch Y (1975) Rate of flow of digesta and electrical activity of the small intestina in dog and sheep. J Physiol (Lond) 249: 69-85.
Bueno L, Fioramonti J, Ruckebusch Y (1977) Mechanisms of propulsion in the small intestine. Ann Rech Vet 8: 293-301.
Bueno L, Ruckebusch Y (1979) Perinatal dvelopment of intestinal myoelectrical activity in dogs and sheep. Am J Physiol 237: E61-E67.
Bühner S, Ehrlein H-J (1989) Characteristics of postprandial duodenal motor patterns in dogs. Dig Dis Sci 34: 1873-1881.
Castedal M, Björnsson E, Abrahamsson H (1998) Postprandial peristalsis in the human duodenum. Neurogastroenterol Motil 10: 227-233.
Code CF, Schlegel JF (1973) The gastrointestinal interdigestive housekeeper: motor correlates of the interdigestive myoelectric complex of the dog. In: Proc. 4th International Symposium of Gastrointestinal Motility. Daniel EE (ed), Mitchell Press,
Vancouver: pp 631-634.
Defilippi C (2003) Canine small bowel motor activity in response to intraduodenal infusion of nutrient mixtures of increasing caloric load in dogs. Dig Dis Sci 48: 1482-1486.
Defilippi C (2007) Patterns of small intestinal motor activity during intraluminal infusion of elementary diet in dogs. Dig Dis Sci 52:702-710.
Dent J, Dodds WJ, Sekiguchi T, Hogan WJ, Arndorfer RC (1983) Interdigestive phasic contractions of the human lower esophageal sphincter. Gastroenterology 84: 453-460.
Fioramonti J, Bueno L (1988) Hormonal control of gut motility in ruminants and non-ruminants and its nutritional implications. Nutr Res Rev 1: 169-188.
Fleckenstein P, Bueno L, Fioramonti J, Ruckebusch Y (1982) Minute rhythm of electrical spike bursts of the small intestine in different species. Am J Physiol 242: G654-G659.
Granger DN, Barrowman JA, Kvietys PR (1985) Clinical Gastrointestinal Physiology. WB Saunders Company, Philadelphia: pp. 1-280.
Heddle R, Miedema BW, Kelly KA (1993) Integration of canine proximal gastric, antral, pyloric, and proximal duodenal motility during fasting and after a liquid meal. Dig Dis Sci 38: 856-869.
Husebye E (1999) The patterns of small bowel motility: physiology and implications in organic disease and functional disorders. Neurogastroenterol Motil 11: 141-161.
Kerlin P, Phillips S (1982) Variability of motility of the ileum and jejunum in healthy humans. Gastroenterology 82: 694-700.
Kruis W, Azpiroz F, Phillips SF (1985) Contractile patterns and transit of fluid in canine terminal ileum. Am J Physiol 249: G264-G270.
Ledeboer M, Masclee AA, Coenraad M, Vecht J, Biemond I, Lamers CB (1999) Antroduodenal motility and small bowel transit during continuous intraduodenal or intragastric administration of enteral nutrition. Eur J Clin Invest 29: 615-623.
Lester GD, Bolton JR (1994) Effect of dietary composition on abomasal and duodenal myoelectrical activity. Res Vet Sci. 57: 270-276.
Malbert CH, Ruckebusch Y (1988) Gastroduodenal motor activity associated with gastric emptying rate in sheep. J Physiol (Lond) 401: 227-239.
McCoy EJ, Baker RD (1968) Effect of feeding on electrical activity of dog’s small intestine. Am J Physiol 214: 1291-1295.
Ooms L, Oyaert W (1978) Electromyographic study of the abomasal antrum and proximal duodenum in cattle. Zbl Ve Med A 25: 464-473.
Poncet C, Ivan M (1984) Effect of duodenal cannulation in sheep on the pattern of gastroduodenal electrical activity and digestive flow Reprod Nutr Dévelop 24: 887-902.
Romański KW (2002) Characteristics and cholinergic control of the ‘minute rhythm’ in ovine antrum, small bowel and gallbladder. J Vet Med A 49: 313-320.
Romański KW (2003) Character and cholinergic control of myoelectric activity in ovine duodenal bulb: relationships to adjacent regions. Vet Arhiv 73: 1-16.
Romański KW (2004) Ovine model for clear-cut study on the role of cholecystokinin in antral, small intestinal and gallbladder motility. Pol J Pharmacol 56: 247-256.
Romański KW (2007a) The effect of cholecystokinin-octapeptide and cerulein on phasic and tonic components in ovine duodenum with special references to the ‘minute rhythm’. Acta Vet Brno 76: 17-25.
Romański KW (2007b) Regional differences in the effects of various doses of cerulein upon the small-intestinal migrating motor complex in fasted and non-fasted sheep. J Anim Physiol Anim Nutr 91: 29-39.
Romański KW (2009a) Cholecystokinin-dependent selective inhibitory effect on ‘minute rhythm’ in the ovine small intestine. Animal 3:275-286.
Romański KW (2009b) Cholecystokinin octapeptide and cerulein inhibit ovine duodenal motility in a dose- and region-specific manner. Bull Vet Inst Pulawy 53: 251-256.
Romański KW (2010) Dose-related effects of cerulein short infusions on proximal small bowel motility in sheep. J S Afr Vet Assoc 81: 27-32.
Ruckebusch Y (1970) The electrical activity of the digestive tract of the sheep as indication of the mechanical events in various regions. J Physiol (Lond) 210: 857-882.
Ruckebusch Y (1988). Motility of the gastrointestinal tract. In: The Ruminant Animal. Digestive Physiology and Nutrition. Church DC (ed), A Reston Book, Prentice Hall, Englewood Cliffs: pp 64-107.
Ruckebusch Y (1989) Motility of the gut during development. In: Lebenthal E (ed) Raven Press, New York: pp 183-206.
Ruckebusch Y, Bueno L (1977) Migrating myoelectrical complex in the small intestine. An intrinsic activity mediated by the vagus. Gastroenterology 73: 1309-1314.
Sarna SK (1985) Cyclic motor activity; migrating motor complex: 1985. Gastroenterology 89: 894-913.
Sarna SK, Otterson MF (1989) Small intestinal physiology and pathophysiology. Gastroenterol Clin North Am 18: 375-405.
Sarna SK, Soergel KH, Harig JM, Loo FD, Wood CM, Donahue KM, Ryan RP, Arndorfer RC (1989) Spatial and temporal patterns of human jejunal contractions. Am J Physiol 257: G423-G432.
Schönfeld JV, Evans DF, Renzing K, Castillo FD, Wingate DL (1998) Human small bowel motor activity in response to liquid meals of different caloric value and different chemical composition. Dig Dis Sci 43: 265-269.
Schwartz MP, Samsom M, Smout AJPM (2001) Human duodenal motor activity in response to acid and different nutrients. Dig Dis Sci 46:1472-1481.
Snedecor GW, Cochran WG (1971) Statistical Methods. 6th ed. The Iowa State University Press, Ames, Iowa: pp 1-580.
Soffer EE, Adrian TE (1992) Effect of meal composition and sham feeding on duodenojejunal motility in humans. Dig Dis Sci 37: 1009-1014.
Staumont G, Delvaux M, Fioramonti J, Berry P, Bueno L, Frexinos J (1992) Differences between jejunal myoelectric activity after a meal and during phase 2 of migrating motor complex in healthy humans. Dig Dis Sci 37: 1554-1561.
Summers RW, Dusdieker NS (1981) Patterns of spike burst spread and flow in the canine small intestine. Gastroenterology 81: 742-750.
Szurszewski JH, Code CF (1968) Activity fronts of the canine small intestine. Gastroenterology 54: 1304 (abstr).
Thor K, Rosell S, Rökaeus Ǻ, Kager L (1982) (Gln4)-neurotensin changes the motility pattern of the duodenum and proximal jejunum from a fasting-type to a fed-type. Gastroenterology 83: 569-574.
White CM, Poxon V, Alexander-Williams J (1983) Effects of nutrient liquids on human gastroduodenal motor activity. Gut 24: 1109-1116.