Pathological findings of severe pancreatolithiasis in a cow

Published: Jan 29, 2018
pancreatolithiasis pathological findings cow

The aim of this study was to describe macroscopic and microscopic characteristics of pancreatolithiasis in a cow. On post mortem examination, severe pancreatolithiasis or a large numbers of white stones with rough surfaces and the ectasis of pancreatic ducts were observed in a female dead cow. Histopathological examination of the affected pancreas revealed focal dilation of exocrine pancreatic acini, atrophy of the acini epithelial cells, infiltrations of lipocytes, mild cystic dilatation of the glands, squamous metaplasia and infiltration of chronic inflammatory cells in the pancreatic ducts wall. The histopathological results of this study showed that pancreatolithiasis can cause microscopic changes in the affected pancreas that some of these lesions have not previously been reported in pancreatolithiasis. Further studies are needed to find out the effects of these microscopic changes on the gland functions in cow.

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Bailiff NL, Norris CR, Seguin B, Griffey SM, and Ling GV (2004). Pancreatolithiasis and pancreatic pseudobladder associated with pancreatitis in a cat. J. Am. Anim. Hosp. Assoc., 40: 69-74.
Charles JA (2007). Pancreas. In: Jubb, Kennedy, and Palmer,s Pathology of Domestic Animal. Vol. 2 Maxie MG (Ed.). 5th Edn. Elsevier Saunders, Edinburgh, New York. pp. 404-405.
Furukawa M, Okuhama Y, Sakai T, Miyashita K, Mine Y, Sasaki M, Kondo S, Sakamoto Y and Tokunaga Y (1996). Extracorporeal Shock Wave Lithotripsy (ESWL) without Endoscopic Lithotomy for Pancreatolithiasis: A Report of Two Cases. Acta Med. Nagasaki, 41: 80-83.
Hayakawa T, Kondo T, Shibata T, Kitagawa M, Sobajima H, Sakai Y, Ishiguro H, Nakae Y, Tanikawa M and Naruse S (1993). Longitudinal changes of plasma pancreatic enzymes and hormones in experimental pancreatolithiasis in dogs. Dig. Dis. Sci., 38: 098-2103.
Koizumi M and Takashi ABE (2005). The etiology of pancreatolithiasis. J. Biliary Tract Pancreas, 26: 869-873.
Konishi K, Izumi R, Kato O, Yamaguchi A and Miyazaki I (1981).Experimental pancreatolithiasis in the dog. Surg., 89: 687-691.
Madany J, Karpinski M and Slowik T (2014). Pancreatolithiasis with the enlargement of pancreatic ducts in cat. Zycie Weterynaryjne, 89: 235-237.
Okumura N, Sakakibara A, Hayakawa T and Noda A (1982). Pancreatic endocrine function in experimental pancreatolithiasis in dogs. Am. J. Gastroenterol., 77: 392-396.
Sakakibara A, Okumura N, Hayakawa T and Kanzaki M (1982). Ultrastructural changes in the exocrine pancreas of experimental pancreatolithiasis in dogs. Am. J. Gastroenterol., 77: 498-503.
Suzuki Y, Sugiyama M, Inui K, Igarashi Y, Ohara H, Tazuma S, Tsuji T, Miyagawa H and Atomi Y (2010). Management for pancreatolithiasis-A Japanese multicenter study. Pancreas, 39:693-694.