| More

Oxidative stress indices and pathological changes in cattle with traumatic pericarditis

Views: 92 Downloads: 76
A. H. HUSSEIN, K. E. HANAN, O. E. YASMIN
A. H. HUSSEIN, K. E. HANAN, O. E. YASMIN

Abstract


Objectives of the study were to provide information on the changes in oxidative stress indices, as well as to describe the possible pathological changes in cattle affected with traumatic pericarditis (TP). Twenty-six cattle with TP were included in the current study. Nine clinically healthy cattle were enrolled as controls. Blood serum samples were collected and stored at -20ºC. Measurement of nitric oxide (NO), malondialdehyde (MDA), total antioxidant capacity (TAC) and other biochemical parameters were done within one week from sampling. Postmortem and histopathological examinations were carried for dead or euthanized cases. The mean values of NO, MDA, creatinine, total bilirubin, globulins, blood urea nitrogen, and total proteins were significantly higher in the diseased group (P<0.05), while the mean values of TAC, glucose and albumin were significantly lowered in TP group (P<0.05). The activities of aspartate aminotransferase (AST) and γ-glutamyl transferase (GGT) were higher in affected cattle than healthy ones. In cattle with TP, a strong significant positive association was found between serum concentrations of NO and MDA. Postmortem examinations of the dead animals revealed severe thickening of the pericardium and accumulation of pericardial effusions either mild or severe in the pericardial sacs. Regarding the recorded histopatholgical changes; Organized fibrinous pericarditis (constrictive pericarditis), necrosis of the myofiber with congestion and hemorrhage in the myocardium, chronic venous congestion of the liver, and hemosiderosis of the spleen were clearly observed. Furthermore, hemorrhage and interstitial fibrosis of the lung, various degrees of degeneration and hyalinization of the renal tubules were prominently featured. In conclusion, oxidative stress and lipid peroxidation may be involved in the complications of traumatic pericarditis in cattle.


Keywords


Cattle; traumatic pericarditis; Oxidative stress; pathological findings

Full Text:

PDF

References


Atakisi E, Kart A, Atakisi O, Topcu B (2009) Acute tamoxifen treatment increases nitric oxide level but not total antioxidant capacity and adenosine deaminase activity in the plasma of rabbits. Eur Rev Med Pharmacol Sci 13:239-43.

Athar H, Parrah JD, Moulvi BA, Singh M, Dedmari FH (2012) Pericarditis in Bovines: A Review . International Journal of Advanced Veterinary Science and Technology. 1 (1): 19-27.

Bancroft TD, Stevens A, Turner DR (1996) Theory and practice of histological technique, fourth ed. Churchill, Livingston, New York, London, San Francisco, Tokyo.

Barker IK, Van Dreumel AA (1985) The alimentary system; foreignbodies in the forestomachs. In: Pathology of domestic animals. 3rd ed, Academic Press, New York: pp 32-33.

Bexiga R, Mateus A, Philbey AW, Ellis K, Barrett D, Meller D (2008) Clinicopathological Presentation of Cardiac Disease in Cattle and Its Impact on Decision Making. Vet Rec 162:575-580.

Braun U (2009) Traumatic pericarditis in cattle: clinical, radiographic and ultrasonographic findings. Vet J 182 (2):176-86.

Braun U, Lejeune G, Schweizer M, Puorger E (2007) Clinical findings in 28 cattle with traumatic pericarditis. Vet Rec 161:558-563.

Elhanafy MM, French DD (2012) Atypical Presentation of Constrictive Pericarditis in a Holstein Heifer. Case Reports in Veterinary Medicine. Article ID 604098, 5 pages, doi:10.1155/2012/604098

Gitto E, Reiter R J, Karbownik M, Tan DX, Gitto P, Barberi S, Barberi I (2002) Causes of oxidative stress in the pre- and perinatal period. Biol Neonate 8:146-157.

Gründer HD (2002) Krankheiten des Herzens und Herzbeutels. In: Innere Medizin und Chirurgie des Rinds. 4th ed, Parey Buch Verlag, Berlin: pp 159-181.

Gutteridge JM (1995) Lipid peroxidation and antioxidants as biomarkers of tissue damage. Clin Chem 41:1819–1828.

Hanan KE, Mottelib AA, Abdel All TS, Wally NE, Baiomy AA, Mohamed AE (2013) Impact of vitamin E and selenium supplementation on oxidative stress indices during transitional period of buffaloe cows. In: Proceeding of XVI International Congress on Animal Hygiene, Nanjing, China: pp 339-343.

Heidarpour M, Mohri M, Borji H, Moghdass E (2013) Oxidant/antioxidant status in cattle with liver cystic echinococcosis. Vet Parasitol 195:131-135.

Hennig B, Chow DK (1988) Lipid peroxidation and endothelial cell injury: implications in atherosclerosis. Free Radic Biol Med 4:99–106

Hussein HA, Staufenbiel R (2014) Clinical presentation and ultrasonographic findings in buffaloes with congestive heart failure. Turkish J Vet Anim Sci 38:534-545.

Jackson PG, Cockcroft PD (2002) Clinical examination of farm animals. Blackwell Science Ltd, USA: pp9-140.

Jesty SA, Sweeney RW, Dolente BA (2005) Idiopathic pericarditis and cardiac tamponade in two cows. J Amer Vet Med Assoc 226:1555-1558.

Koracevic D, Koracevic G, Djordjevic V, Andrejevic S, Cosic V (2001) Method for the measurement of antioxidant activity in human fluids. J Clin Pathol 54:356-361.

Lightboy JH, Stevenson LM, Jackson F, Donaldson K, Jones DG (2001) Comparative aspects of plasma antioxidant status in sheep and goats, and the influence of experimental abomasal nematode infection. J Comp Pathol 124:192-199.

Montgomery HAC, Dymock JF (1961) Colorimetric determination of nitric oxide. Analyst 86:414-417.

Misk NA, Nigam JM, Rifat JF (1984) Management of foreign body syndrome in Iraqi cattle. Agric Pract 5:19-21.

Ohkawa H, Ohishi N, Yagi K (1979) Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 95(2):351-358.

Perkins SL, Magdesian KG, Thomas WP, Spier SJ (2004) Pericarditis and pleuritis Caused By C. Pseudotuberculosis in a Horse. J Am Vet Med Assoc 224:1133-1138.

Radostits OM, Gay CC, Hinchcliff KW, Constable PD (2007) Veterinary Medicine, 10th ed, W. B. Saunders, England: pp 337-344.

Roth L, King JM (1991) Traumatic reticulitis in cattle: a review of 60 fatal cases. J Vet Diag Invest 3:52-54.

Serdar Z, Yesilbursa D, Dirican M, Sarandol E, Serdar A (2007) Sialic acid and oxidizability of lipid and proteins and antioxidant status in patients with coronary artery disease. Cell Biochem Funct 25(6):655-564.

Solomons TWG, Fryhle CB (2002) Radical reactions. In: Organic Chemistry. 7th ed, Wiley, New York: pp 146-211.

Tennant B, Center S (2008) Hepatic function. In: Kaneko JJ, Harvey JW, Bruss ML. editors. Clinical Biochemistry of Domestic Animals. 6th ed, Academic Press, New York, USA: pp 379-412.

Trevisan M, Browne R, Ram M, Muti P, Freundenheim J, Carosella AN, Armstrong D (2001) Correlates of markers of oxidative status in the general populatin. Am J Epidemiol 154:348-356.

Yang FL, Li XS, He BX, Yang XL, Li GH, Liu P, Huang QH, Pan MX, Li J (2011) Malondialdehyde level and some enzymatic activities in subclinical mastitis milk. African J of Biotech 10:5534-5538.


Refbacks

  • There are currently no refbacks.


Copyright (c) 2018 AH HUSSEIN, KE HANAN, OE YASMIN

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.