Relationship between body condition score, blood metabolites and oxidative stress in transition period and reproductive performance of dairy cows
Keywords:
body condition score cow fertility oxidative stress metabolites transition period
Abstract
The aim of the current study was to investigate the relationship between prepartum body condition score (BCS), blood metabolites (Glucose, beta-hydroxybutyrate; BHB), oxidative stress (Malondialdehyde; MDA, Glutathione peroxidase; GSH-Px) in transition period and some reproductive parameters in Holstein dairy cows. Fifty cows were divided into two groups [low-BCS = 2.75-3.0 (n=25); adequate-BCS = 3.25-3.75 (n=25)] according to BCS on the 21st day before expected calving. BCS was also recorded at 0 and +21 days after calving. Blood samples collected at -21, 0 and +21 days from calving for MDA and GSH-Px analysis as well as at -21, +14 and +21 days of postpartum for glucose and BHB. Data on reproductive parameters obtained from farm records were also collected. MDA concentrations were higher in group of low-BCS compared to group of adequate-BCS at -21 and 0 d related to calving (p<0.05). GSH-Px activity was lower in group of low-BCS than adequate one during the transition period (p<0.05). Low-BCS group also showed higher concentrations of BHB at +14 and +21 days after calving. During the transition period, low-BCS group had lower glucose concentrations compared to adequate one (p<0.05). Adequate-BCS group of cows showed shorter intervals of calving to first estrus (p<0.01) and calving to conception (p<0.01). In conclusion, cows with lower BCS at the prepartum period had worse metabolic and oxidative balance during the transition period. This situation also was associated with worse reproductive performance in cows.
Article Details
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ÇOLAKOĞLU, H. E., YAZLIK, M. O., KAYA, U., KURT, S., BAYRAMOĞLU, R., VURAL, R., & KÜPLÜLÜ, Ş. (2020). Relationship between body condition score, blood metabolites and oxidative stress in transition period and reproductive performance of dairy cows. Journal of the Hellenic Veterinary Medical Society, 71(1), 2041–2046. https://doi.org/10.12681/jhvms.22954
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- Vol. 71 No. 1 (2020)
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- Research Articles
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References
Alharthi A, Zhou Z, Lopreiato V, Trevisi E, Loor JJ. 2018. Body condition score prior to parturition is associated with plasma and adipose tissue biomarkers of lipid metabolism and inflammation in Holstein cows. J Anim Sci Biotechnol. 9: 12.
Appasamy M, Jauniaux E, Serhal P, Al-Qahtani A, Groome NP, Muttukrishna S. 2008. Evaluation of the relationship between follicular fluid oxidative stress, ovarian hormones, and response to gonadotropin stimulation. Fertil Steril. 89: 912-921.
Barletta RV, Maturana Filho M, Carvalho PD, Del Valle TA, Netto AS, Renno FP, Mingoti RD, Gandra JR, Mourao GB, Fricke PM, et al. 2017. Association of changes among body condition score during the transition period with NEFA and BHBA concentrations, milk production, fertility, and health of Holstein cows. Theriogenology 104:30-36.
Bernabucci U, Ronchi B, Lacetera N, Nardone A. 2005. Influence of body condition score on relationships between metabolic status and oxidative stress in periparturient dairy cows. J Dairy Sci 88: 2017-2026.
Buckley F, O’Sullivan K, Mee JF, Evans RD, Dillon P. 2003. Relationships among milk yield, body condition, cow weight, and reproduction in spring-calved Holstein-Friesians. J Dairy Sci 86: 2308-2319.
Chapel JM, Diez Muino R, Pereira V, Castillo C, Hernandez J, Benedito JL. 2017. Relationship of BCS prepartum with reproductive performance and lipomobilization in Holstein dairy cows. Pak Vet J. 37:215-219.
Colakoglu HE, Yazlik MO, Kaya U, Colakoglu EC, Kurt S, Oz B, Bayramoglu R, Vural MR, Kuplulu S. 2017. MDA and GSH-Px activity in transition dairy cows under seasonal variations and their relationship with reproductive performance. J Vet Res. 61: 497-502.
Delfino NC, Bulcao LFA, Alba HDR, Oliveira MXDS, Queiroz FPS, Carvalho GGP, Renno FP, Freitas Junior JE. 2018. Influence of body condition score at calving on the metabolic status and production performance of Murrah buffaloes (Bubalus bubalis) during the transition period. Asian-Australas J Anim Sci. 00:1-10.
Ferguson JD, Galligan DT, Thomsen T. 1994. Principal descriptors of body condition score in Holstein cows. J Dairy Sci. 77: 2695-2703.
Festila I, Miresan V, Raducu C, Cocan D, Constantinescu R, Coroian A. 2012. Evaluation of oxidative stress in dairy cow through antioxidant enzymes glutathione peroxidase (GPX) and superoxide dismutase (SOD). Bulletin UASVM Animal Science and Biotechnologies 69:107-110.
Folnozic I, Turk R, Duricic D, Vince S, Pleadin J, Flegar-Mestric Z, Valpotic H, Dobranic T, Gracner D, Samardzija M. 2015. Influence of body condition on serum metabolic indicators of lipid mobilization and oxidative stress in dairy cows during the transition period. Reprod Dom Anim. 50: 910-917.
Furukawa S, Fujita T, Shimabukuro M, Iwaki M, Yamada Y, Nakajima Y, Nakayama O, Makishima M, Matsuda M, Shimomura I. 2004. Increased oxidative stress in obesity and its impact on metabolic syndrome. J Clin Invest. 114: 1752-1761.
Gheise NJE, Riasi A, Shahneh AZ, Celi P, Ghoreishi SM. 2017. Effect of pre-calving body condition score and previous lactation on BCS change, blood metabolites, oxidative stress and milk production in Holstein dairy cows. Ital J Anim Sci. 16: 474-483.
Godara AS, Tomar AKS, Bhat SA, Patel BHM, Singh Godara R. 2016. Effect of pre partum body condition score on productive, reproductive and calf birth weight performance in Tharparkar cattle. I.J.S.N. 7: 177-180.
Konvicna J, Vargova M, Pulikova I, Kovac G, Kostecka Z. 2015. Oxidative stress and antioxidant status in dairy cows during prepartal and postpartal periods. Acta Vet Brno 84: 133-140.
Laubenthal L, Ruda L, Sultana N, Winkler J, Rehage J, Meyer U, Danicke S, Sauerwein H, Haussler S. 2017. Effect of increasing body condition on oxidative stress and mitochondrial biogenesis in subcutaneous adipose tissue depot of nonlactating dairy cows. J Dairy Sci. 100:4976-4986.
Leroy JL, Vanholder T, Opsomer G, Van Soom A, De Kruif A. 2006. The in vitro development of bovine oocytes after maturation in glucose and beta-hydroxybutyrate concentrations associated with negative energy balance in dairy cows. Reprod Dom Anim. 41: 119-123.
Lucy MC, Butler ST, Garverick HA. 2014. Endocrine and metabolic mechanisms linking postpartum glucose with early embryonic and foetal development in dairy cows. Animal. 8: 82-90.
Megahed GA, Anwar MM, Wasfy SI, Hammadeh ME. 2008. Influence of heat stress on the cortisol and oxidant-antioxidants balance during oestrous phase in buffalo-cows (Bubalus bubalis): Thermo-protective role of antioxidant treatment. Reprod Dom Anim. 43: 672-677.
O’Boyle N, Corl CM, Gandy JC, Sordillo LM. 2006. Relationship of body condition score and oxidant stress to tumor necrosis factor expression in dairy cattle. Vet Immunol Immunopathol. 113: 297-304.
Ozkaya MO, Nazıroglu M. 2010. Multivitamin and mineral supplementation modulates oxidative stress and antioxidant vitamin levels in serum and follicular fluid of women undergoing in vitro fertilization. Fertil Steril. 94: 2465-2460.
Pasquini A, Roberti S, Meucci V, Luchetti E, Canello S, Guidetti G, Biagi G. 2013. Association between body condition and oxidative status in dogs. FNS. 4: 191-196.
Pilarczyk B, Jankowiak D, Tomza-Marciniak A, Pilarczyk R, Sablik P, Drozd R, Tylkowska A, Skolmowska M. 2012. Selenium concentration and glutathione peroxidase (GSH-Px) activity in serum of cows at different stages of lactation. Biol Trace Elem Res. 147: 91-96.
Roche JR, Macdonald KA, Burke CR, Lee JM, Berry DP. 2007. Associations among body condition score, body weight and reproductive performance in seasonal calving dairy cattle. J Dairy Sci. 90: 376-391.
Roh HT, Cho SY, So WY. 2017. Obesity promotes oxidative stress and exacerbates blood-brain barrier disruption after high-intensity exercise. JSHS. 6: 225-230.
Stefanska B, Pozniak S, Nowak W. 2016. Relationship between the preand postpartum body condition scores and periparturient indices and fertility in high-yielding dairy cows. J Vet Res. 60: 81-90.
Sharma N, Singh NK, Singh OP, Pandey V, Verma PK. 2011. Oxidative stress and antioxidant status during transition period in dairy cows. Asian-Aust J Anim Sci. 24: 479-484.
Turk R, Podpecan O, Mrkun J, Flegar-Mestric Z, Perkov S, Zrimsek P. 2015. The effect of seasonal thermal stress on lipid mobilisation, antioxidant status and reproductive performance in dairy cows. Reprod Dom Anim. 50: 595-603.
Walsh RB, Kelton DF, Duffield TF, Leslie KE, Walton JS, LeBlanc SJ. 2007 Prevalence and risk factors for postpartum anovulatory condition in dairy cows. J Dairy Sci. 90: 315-24.
Vincent HK, Taylor AG. 2006. Biomarkers and potential mechanisms of obesity-induced oxidant stress in humans. Int J Obes. 30: 400-18.
