Injection site sarcomas in other species than the domestic cat


Keywords:
Injection site sarcoma oncology cancer animals
J STANS
Abstract

Injection site sarcomas (ISS) are tumours of tissues of mesenchymal origin that occur at an injection site. These tumours have been mainly described in cats as Feline injection-site sarcoma (FISS), but suspected cases have also been described in other species such as dogs. In other species than the domestic cat, these tumours are however much rarer. As a result, the body of literature is limited. This review aims to summarize the knowledge regarding ISS in species other than the domestic cat. In general, it seems that ISS can occur in a wide range of animals and that similar treatment strategies are employed as in cats. Like in cats, it seems that the benefit of the reasons for injection (such as vaccination and microchip implantation) could outweigh the risk of ISS development in other species.

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References
Carneiro, C. S., de Queiroz, G. F., Pinto, A. C., Dagli, M. L., & Matera, J. M. (2019). Feline injection site sarcoma: immunohistochemical characteristics. J Feline Med Surg, 21(4), 314-321. https://doi.org/10.1177/1098612X18774709
Cohen, M., Wright, J. C., Brawner, W. R., Smith, A. N., Henderson, R., & Behrend, E. N. (2001). Use of surgery and electron beam irradiation, with or without chemotherapy, for treatment of vaccine-associated sarcomas in cats: 78 cases (1996-2000). J Am Vet Med Assoc, 219(11), 1582-1589. https://doi.org/10.2460/javma.2001.219.1582
Doddy, F. D., Glickman, L. T., Glickman, N. W., &Janovitz, E. B. (1996). Feline fibrosarcomas at vaccination sites and non-vaccination sites. J Comp Pathol, 114(2), 165-174. https://doi.org/10.1016/s0021-9975(96)80005-3
Hartmann, K., Day, M. J., Thiry, E., Lloret, A., Frymus, T., Addie, D., Boucraut-Baralon, C., Egberink, H., Gruffydd-Jones, T., Horzinek, M. C., Hosie, M. J., Lutz, H., Marsilio, F., Pennisi, M. G., Radford, A. D., Truyen, U., Möstl, K., & Diseases, E. A. B. o. C. (2015). Feline injection-site sarcoma: ABCD guidelines on prevention and management. J Feline Med Surg, 17(7), 606-613. https://doi.org/10.1177/1098612X15588451
Hendrick, M. J., Shofer, F. S., Goldschmidt, M. H., Haviland, J. C., Schelling, S. H., Engler, S. J., & Gliatto, J. M. (1994). Comparison of fibrosarcomas that developed at vaccination sites and at nonvaccination sites in cats: 239 cases (1991-1992). J Am Vet Med Assoc, 205(10), 1425-1429.
Jacobs, T. M., Poehlmann, C. E., &Kiupel, M. (2017). Injection-Site Sarcoma in a Dog: Clinical and Pathological Findings. Case Rep Vet Med, 2017, 6952634. https://doi.org/10.1155/2017/6952634
Kannegieter, N. J., Schaaf, K. L., Lovell, D. K., Simon, C. D., & Stone, B. M. (2010). Myofibroblastic fibrosarcoma with multifocal osseous metaplasia at the site of equine influenza vaccination. Aust Vet J, 88(4), 132-136. https://doi.org/10.1111/j.1751-0813.2010.00557.x
Kass, P. H., Spangler, W. L., Hendrick, M. J., McGill, L. D., Esplin, D. G., Lester, S., Slater, M., Meyer, E. K., Boucher, F., Peters, E. M., Gobar, G. G., Htoo, T., & Decile, K. (2003). Multicenter case-control study of risk factors associated with development of vaccine-associated sarcomas in cats. J Am Vet Med Assoc, 223(9), 1283-1292. https://doi.org/10.2460/javma.2003.223.1283
Kinne, J., &Tarello, W. (2007). Vaccine-associated fibrosarcoma in a lion (Panthera leo) [Article]. Revue De MedecineVeterinaire, 158(2), 73-74.
Munday, J. S., Stedman, N. L., & Richey, L. J. (2003). Histology and immunohistochemistry of seven ferret vaccination-site fibrosarcomas. Vet Pathol, 40(3), 288-293. https://doi.org/10.1354/vp.40-3-288
Petterino, C., Modesto, P., Strata, D., Vascellari, M., Mutinelli, F., Ferrari, A., & Ratto, A. (2009). A case of interscapular fibrosarcoma in a dwarf rabbit (Oryctolagus cuniculus). J Vet DiagnInvest, 21(6), 900-905. https://doi.org/10.1177/104063870902100626
Saba, C. F. (2017). Vaccine-associated feline sarcoma: current perspectives. Vet Med (Auckl), 8, 13-20. https://doi.org/10.2147/VMRR.S116556
Selmic, L. E., Griffin, L. R., Rector, M. H., Lafferty, M., Pool, R., & Ehrhart, N. P. (2016). Treatment of extraskeletal osteosarcoma at a previous injection site resulting in prolonged survival in 1 dog. Can Vet J, 57(9), 950-954.
Vascellari, M., Melchiotti, E., Bozza, M. A., &Mutinelli, F. (2003). Fibrosarcomas at presumed sites of injection in dogs: characteristics and comparison with non-vaccination site fibrosarcomas and feline post-vaccinal fibrosarcomas. J Vet Med A PhysiolPathol Clin Med, 50(6), 286-291. https://doi.org/10.1046/j.1439-0442.2003.00544.x
Vascellari, M., Melchiotti, E., & Mutinelli, F. (2006). Fibrosarcoma with typical features of postinjection sarcoma at site of microchip implant in a dog: histologic and immunohistochemical study. Vet Pathol, 43(4), 545-548. https://doi.org/10.1354/vp.43-4-545
Woodward, K. N. (2011). Origins of injection-site sarcomas in cats: the possible role of chronic inflammation-a review. ISRN Vet Sci, 2011, 210982. https://doi.org/10.5402/2011/210982
Zabielska-Koczywąs, K., Wojtalewicz, A., &Lechowski, R. (2017). Current knowledge on feline injection-site sarcoma treatment. Acta Vet Scand, 59(1), 47. https://doi.org/10.1186/s13028-017-0315-y
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