Metabolomics characteristics associated with milk yield and milk quality in sheep


Published: Οκτ 26, 2022
Keywords:
Amino acid profile Awassi milk sheep somatic cell count
M Kahraman
https://orcid.org/0000-0002-7757-2483
A Das
https://orcid.org/0000-0003-0371-5434
G Gungoren
https://orcid.org/0000-0002-0360-7735
B Dogan Das
https://orcid.org/0000-0003-2163-2632
H Yalcin
https://orcid.org/0000-0003-0733-7821
M Hitit
https://orcid.org/0000-0001-5636-061X
İ Koyuncu
https://orcid.org/0000-0002-9469-4757
S Akmese
https://orcid.org/0000-0003-4992-0281
Abstract
Standart süt testleri, süt verimi ve kalitesi gibi izleme özelliklerini içerir. Standart süt testlerinin yapılmasına ek olarak, süt özelliklerini belirlemek için potansiyel biyobelirteçler olarak hareket edebilecek metabolitleri değerlendirmek artık mümkün. Bu çalışma İvesi koyunlarında süt verimi ve kalitesi ile ilgili metabolomik parametreleri belirlemek amacıyla yapılmıştır. Çalışmamızda süt verimi yüksek 13, süt verimi düşük 13 olmak üzere toplam 26 İvesi koyunu incelenmiştir. Metabolomik analiz için sıvı kromatografi tandem kütle spektrometrisi kullanıldı. Aspartik asit, ornitin, anserin ve sistatiyonin düzeyleri açısından iki grup arasında farklı düzeylerde istatistiksel olarak anlamlı fark vardı (P<0.05 ve P<0.01). Süt verimi ile aspartik asit (r=-0,630) ve anserin (r=-0. 522) seviyeleri (P<0.01). Laktoz seviyeleri ile lizin (r=−0.501), alfa-aminoadipik asit (r=−0.524) ve hidroksilizin (r=−0.511) seviyeleri arasında anlamlı bir negatif korelasyon bulundu (P<0.01). Somatik hücre sayısı ve alanin (r=0,493), aspartik asit (r=0,418), prolin (r=0,421), alfa-aminoadipik asit (r=0,407), beta-alanin (r=0,433) ve tiyaprolin (r =0.434) seviyeleri (P<0.05) pozitif korelasyon gösterdi. Sonuçlarımız, koyun sütü verimi ve süt kalitesiyle ilgili metabolik olaylar hakkında, süt üretimini iyileştirmek ve koyun sütünün bileşenlerini geliştirmek için daha ileri araştırmalara rehberlik edebilecek önemli bilgiler sağlar. Somatik hücre sayısı ve alanin (r=0,493), aspartik asit (r=0,418), prolin (r=0,421), alfa-aminoadipik asit (r=0,407), beta-alanin (r=0,433) ve tiyaprolin (r =0.434) seviyeleri (P<0.05) pozitif korelasyon gösterdi. Sonuçlarımız, koyun sütü verimi ve süt kalitesiyle ilgili metabolik olaylar hakkında, süt üretimini iyileştirmek ve koyun sütünün bileşenlerini geliştirmek için daha ileri araştırmalara rehberlik edebilecek önemli bilgiler sağlar. Somatik hücre sayısı ve alanin (r=0,493), aspartik asit (r=0,418), prolin (r=0,421), alfa-aminoadipik asit (r=0,407), beta-alanin (r=0,433) ve tiyaprolin (r =0.434) seviyeleri (P<0.05) pozitif korelasyon gösterdi. Sonuçlarımız, koyun sütü verimi ve süt kalitesiyle ilgili metabolik olaylar hakkında, süt üretimini iyileştirmek ve koyun sütünün bileşenlerini geliştirmek için daha ileri araştırmalara rehberlik edebilecek önemli bilgiler sağlar.
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Author Biographies
M Kahraman, Harran University

Department of Animal Husbandry, Faculty of Veterinary Medicine, Harran University

A Das, Harran University

Department of Animal Husbandry, Faculty of Veterinary Medicine, Harran University

G Gungoren, Harran University

Department of Animal Husbandry, Faculty of Veterinary Medicine, Harran University

B Dogan Das, Harran University

Department of Animal Nutrition and Nutritional Diseases, Faculty of Veterinary Medicine, Harran University

H Yalcin, Harran University

Department of Biostatistics,Harran University, Faculty of Agriculture, Harran University

M Hitit, Kastamonu University

Department of Genetics,Faculty of Veterinary Medicine, Kastamonu University

İ Koyuncu, Harran University

Department of Biochemistry,Faculty of Medicine, Harran University

S Akmese, Harran University

Program of Pharmacy Services, Vocational School of Health Services, Harran University

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