The efficacy of information interventions for patients undergoing hematopoietic stem cell transplantation: A systematic review of randomized trials
Published:
Apr 11, 2023
Keywords:
Hematopoietic stem cell transplantation quality of life information provision information needs satisfaction
Abstract
Background: The provision of information to patients is one of the most important factors of supportive cancer care. We conducted a systematic review to detect information-giving interventions and their impact on quality of life, psychological distress and satisfaction of hematopoietic stem cell transplant (HSCT) patients.
Methods: Randomized controlled trials (RCTs) from 2010 to 2021 in Pubmed, CINAHL, Cochrane Library and Scopus databases were reviewed.
Results: Eight RCTs with total of 1550 HSCT patients enrolled were identified. Most studies indicated that groups exposed to interventions displayed higher rates of satisfaction. However, the minority of the studies produced significant benefits in terms of distress and quality of life. RCTs were heterogeneous regarding sample size, diagnosis, transplant type and follow-up duration.
Conclusion: Additional research is needed to make definitive conclusions. More longitudinal multicenter studies with consistency in the methodological approach, assessment and interpretation are necessary.
Article Details
- How to Cite
-
Kiropoulou, A., Katsareli , M., Vasileiadis , I., & Nanas , S. (2023). The efficacy of information interventions for patients undergoing hematopoietic stem cell transplantation: A systematic review of randomized trials . Health & Research Journal, 9(2), 115–130. https://doi.org/10.12681/healthresj.33473
- Section
- Systemic Review
Copyright notice:
The journal "Health and Research Journal" reserves the rights for copyright of the content of the website and also the copyright of the articles published.
By virtue of their appearance in this journal, the articles are free to be used for non-commercial purposes. However, the articles cannot and must not be used in anyway, published elsewhere or modified without any reference to the author and the first publication of the article.
Downloads
Download data is not yet available.
References
Henig I, Zuckerman T. Hematopoietic stem cell transplan-tation-50 years of evolution and future perspectives. Ram-bam Maimonides Med J. 2014;5(4):e0028.
Watson R, Bryant J, Sanson-Fisher R, Turon H, Hyde L, Herrmann A. Do haematological cancer patients get the in-formation they need about their cancer and its treatment? Results of a cross-sectional survey. Support Care Cancer. 2019;27(4):1509-1517.
Atilla E, Ataca Atilla P, Demirer T. A Review of Myeloabla-tive vs Reduced Intensity/Non-Myeloablative Regimens in Allogeneic Hematopoietic Stem Cell Transplantations. Bal-kan Med J. 2017;34(1):1-9.
Cheon J, Lee YJ, Jo JC, Kweon K, Koh S, Min YJ, et al. Late complications and quality of life assessment for survivors receiving allogeneic hematopoietic stem cell transplanta-tion. Support Care Cancer. 2021;29(2):975-986.
Hall AE, Sanson-Fisher RW, Lynagh MC, Tzelepis F, D'Este C. What do haematological cancer survivors want help with? A cross-sectional investigation of unmet supportive care needs. BMC Res Notes. 2015;8:221.
Hwang JP, Roundtree AK, Giralt SA, Suarez-Almazor M. Late effects and healthcare needs of survivors of allogeneic stem cell transplantation: a qualitative study. BMJ Support Palliat Care. 2012;2(4):344-50.
Jefford M, Tattersall MH. Informing and involving cancer patients in their own care. Lancet Oncol. 2002;3(10):629-37.
D'Souza A, Pasquini M, Spellecy R. Is 'informed consent' an 'understood consent' in hematopoietic cell transplanta-tion? Bone Marrow Transplant 2015;50(1):10-4.
Forsyth R, Scanlan CL, Kerridge I. Optimising consent and adherence in high-risk medical settings: Nurses’ role as in-formation providers in allogeneic bone marrow transplant. Aust J Cancer Nurs. 2019;20:8–12.
Finset A. How can we promote patient recall of information from medical consultations? Patient Educ Couns. 2015;98(6):683-4.
Atherton K, Young B, Kalakonda N, Salmon P. Perspectives of patients with haematological cancer on how clinicians meet their information needs: "Managing" information ver-sus "giving" it. Psychooncology. 2018;27(7):1719-1726.
Medendorp NM, Visser LNC, Hillen MA, de Haes JCJM, Smets EMA. How oncologists' communication improves (analogue) patients' recall of information. A randomized video-vignettes study. Patient Educ Couns. 2017;100(7):1338-1344.
Raj M, Choi SW, Gurtekin TS, Platt J. Improving the In-formed Consent Process in Hematopoietic Cell Transplan-tation: Patient, Caregiver, and Provider Perspectives. Biol Blood Marrow Transplant. 2018;24(1):156-162.
Alexander SC, Sullivan AM, Back AL, Tulsky JA, Goldman RE, Block SD et al. Information giving and receiving in he-matological malignancy consultations. Psychooncology. 2012;21(3):297-306.
Lehmann V, Labrie NHM, van Weert JCM, van Dulmen S, de Haes HJCJM, Kersten MJ, et al. Tailoring the amount of treatment information to cancer patients' and survivors' preferences: Effects on patient-reported outcomes. Patient Educ Couns. 2020;103(3):514-520.
Rood JA, van Zuuren FJ, Stam F, van der Ploeg T, Eeltink C, Verdonck-de Leeuw IM, et al. Perceived need for infor-mation among patients with a haematological malignancy: associations with information satisfaction and treatment decision-making preferences. Hematol Oncol. 2015;33(2):85-98.
Rood JA, Van Zuuren FJ, Stam F, van der Ploeg T, Huijgens PC, Verdonck-de Leeuw IM. Cognitive coping style (moni-toring and blunting) and the need for information, infor-mation satisfaction and shared decision making among pa-tients with haematological malignancies. Psychooncology. 2015;24(5):564-71.
Husson O, Oerlemans S, Mols F, Smeets RE, Poortmans PM, van de Poll-Franse LV. Satisfaction with information provi-sion is associated with baseline but not with follow-up quality of life among lymphoma patients: Results from the PROFILES registry. Acta Oncol. 2014;53(7):917-26.
Liptrott SJ, Lovell K, Bee P. Influence of Needs and Experi-ences of Haemato-Oncology Patients on Acceptability of a Telephone Intervention for Support and Symptom Man-agement: A Qualitative Study. Clin Nurs Res. 2020;29(8):627-637.
Leppla L, Mielke J, Kunze M, Mauthner O, Teynor A, Valen-ta S, et al. Clinicians and patients perspectives on follow-up care and eHealth support after allogeneic hematopoietic stem cell transplantation: A mixed-methods contextual analysis as part of the SMILe study. Eur J Oncol Nurs. 2020;45:101723.
Maher M, Kaziunas E, Ackerman M, Derry H, Forringer R, Miller K, et al. User-Centered Design Groups to Engage Pa-tients and Caregivers with a Personalized Health Infor-mation Technology Tool. Biol Blood Marrow Transplant. 2016;22(2):349-358.
Lounsberry JJ, Macrae H, Angen M, Hoeber M, Carlson LE. Feasibility study of a telehealth delivered, psychoeduca-tional support group for allogeneic hematopoietic stem cell transplant patients. Psychooncology. 2010;19(7):777-81.
Preussler JM, Denzen EM, Majhail NS, Baker KS, McCann M, Burns LJ, et al. Engaging hematopoietic cell transplantation patients and caregivers in the design of print and mobile application individualized survivorship care plan tools. Support Care Cancer. 2020;28(6):2805-2816.
Runaas L, Hoodin F, Munaco A, Fauer A, Sankaran R, Churay T, et al. Novel Health Information Technology Tool Use by Adult Patients Undergoing Allogeneic Hematopoi-etic Cell Transplantation: Longitudinal Quantitative and Qualitative Patient-Reported Outcomes. JCO Clin Cancer Inform. 2018;2:1-12.
Syrjala KL, Stover AC, Yi JC, Artherholt SB, Romano EM, Schoch G, et al. Development and implementation of an In-ternet-based survivorship care program for cancer survi-vors treated with hematopoietic stem cell transplantation. J Cancer Surviv. 2011;5(3):292-304.
Bryant J, Sanson-Fisher R, Stevenson W, Smits R, Henskens F, Wei A, et al. Protocol of a multi-centre randomised con-trolled trial of a web-based information intervention with nurse-delivered telephone support for haematological cancer patients and their support persons. BMC Cancer. 2015;15:295.
Mekuria AB, Erku DA, Belachew SA. Preferred information sources and needs of cancer patients on disease symptoms and management: a cross-sectional study. Patient Prefer Adherence. 2016;10:1991-1997.
Konstantinidis TI, Spinthouri M, Ramoutsaki A, Marnelou A, Kritsotakis G, Govina O. Assessment of Unmet Supportive Care Needs in Haematological Cancer Survivors. Asian Pac J Cancer Prev. 2019;20(5):1487-1495.
Hall A, Lynagh M, Tzelepis F, Paul C, Bryant J. How can we help haematological cancer survivors cope with the changes they experience as a result of their cancer? Ann Hematol. 2016;95(12):2065-2076.
de Morton NA. The PEDro scale is a valid measure of the methodological quality of clinical trials: a demographic study. Aust J Physiother. 2009;55(2):129-33.
Cioce M, Lohmeyer FM, Moroni R, Magini M, Giraldi A, Garau P, et al. Impact of Educational Interventions on Psy-chological Distress During Allogeneic Hematopoietic Stem Cell Transplantation: A Randomised Study. Mediterr J He-matol Infect Dis. 2020;12(1):e2020067.
Majhail NS, Murphy E, Laud P, Preussler JM, Denzen EM, Abetti B, et al. Randomized controlled trial of individualized treatment summary and survivorship care plans for hema-topoietic cell transplantation survivors. Haematologica. 2019;104(5):1084-1092.
Syrjala KL, Yi JC, Artherholt SB, Romano JM, Crouch ML, Fiscalini AS, et al. An online randomized controlled trial, with or without problem-solving treatment, for long-term cancer survivors after hematopoietic cell transplantation. J Cancer Surviv. 2018;12(4):560-570.
Sarıtürk Ç, Gereklioğlu Ç, Korur A, Asma S, Yeral M, Solmaz S, et al. Effectiveness of Visual Methods in Information Pro-cedures for Stem Cell Recipients and Donors. Turk J Hae-matol. 2017;34(4):321-327.
Horne B, Newsham A, Velikova G, Liebersbach S, Gilleece M, Wright P. Development and evaluation of a specifically designed website for haematopoietic stem cell transplant patients in Leeds. Eur J Cancer Care. 2016;25:402-418.
Braamse AMJ, van Meijel B, Visser OJ, Boenink AD, Cuijpers P, Eeltink CE, et al. A randomized clinical trial on the effec-tiveness of an intervention to treat psychological distress and improve quality of life after autologous stem cell transplantation. Ann Hematol. 2016;95(1):105-114.
Högberg KM, Stockelberg D, Sandman L, Broström A, Nys-tröm M. The meaning of web-based communication for support: from the patients' perspective within a hemato-logical healthcare setting. Cancer Nurs. 2015;38(2):145-54.
David N, Schlenker P, Prudlo U, Larbig W. Internet-based program for coping with cancer: a randomized controlled trial with hematologic cancer patients. Psychooncology. 2013;22(5):1064-72.
Aranda S, Jefford M, Yates P, Gough K, Seymour J, Francis P, et al. Impact of a novel nurse-led prechemotherapy edu-cation intervention (ChemoEd) on patient distress, symp-tom burden, and treatment-related information and sup-port needs: results from a randomised, controlled trial. Ann Oncol. 2012;23(1):222-231.
Iconomou G, Viha A, Koutras A, Koukourikou I, Mega V, Makatsoris T, et al. Impact of providing booklets about chemotherapy to newly presenting patients with cancer: a randomized controlled trial. Ann Oncol. 2006;17:515–520.
Barlési F, Barrau K, Loundou A, Doddoli C, Simeoni MC, Auquier P, et al. Impact of information on quality of life and satisfaction of non-small cell lung cancer patients: a randomized study of standardized versus individualized in-formation before thoracic surgery. J Thorac On-col. 2008;3:1146–1152.
Häggmark C, Bohman L, Ilmoni-Brandt K, Näslund I, Sjödén PO, Nilsson B. Effects of information supply on satisfaction with information and quality of life in cancer patients re-ceiving curative radiation therapy. Patient Educ Couns. 2001;45(3):173-179.
