Testing the limits of Bioethics: the case of DTC Genetic Testing

Σοφία Ζέρβα (Sophia Zerva)
Ολυμπιάδα Λαχανά (Olympiada Lachana)
Ελένη Μπουραζάνη (Eleni Mpourazani)
Ελευθερία Παπουτσάκη (Eleftheria Papoutsaki)
Κωνσταντίνος Πετρόπουλος (Konstantinos Petropoulos)
Μαίρη Χριστοφίδη (Mairy Christophidi)
Θεοδώρα Κάτσιλα (Theodora Katsila)
Γεώργιος Πατρινός (Giorgos Patrinos)

Direct-To-Consumer (DTC) genetic tests are commercial services provided online, in drugstores and/or via television and press devoid of the consultation by a health professional or geneticist. Today, there are issues regarding their data validity and interpretation and the ethics of their use, as they allow access to the users’ genetic makeup.
Indeed, DTC genetic services can influence consumers’ private life as well as the lives of those around them. We feel that DTC genetic tests and services need to be regulated and notably, regulation measures should be standardized among national and multinational regulatory bodies.

Article Details
  • Section
  • Original Articles
Download data is not yet available.
Patrinos GP, et al. Genetic tests obtainable through pharmacies: the good, the bad, and the ugly. Human genomics, 2013. 7(1): 17.
Niemiec E and HC Howard. Ethical issues in consumer genome sequencing: use of consumers' samples and data. Applied & translational genomics, 2016. 8: 23-30.
Howard HC, BM Knoppers, and P Borry, Blurring lines. EMBO reports, 2010. 11(8): 579-582.
Skirton H. Direct to consumer testing in reproductive contexts–should health professionals be concerned? Life sciences, society and policy, 2015. 11(1): 1-9.
Hindorff LA, et al. Potential etiologic and functional implications of genome-wide association loci for human diseases and traits. Proceedings of the National Academy of Sciences, 2009. 106(23): 9362-9367.
Swan M. Multigenic condition risk assessment in direct-to-consumer genomic services. Genetics in Medicine, 2010. 12(5): 279-288.
Mihaescu R, et al., Evaluation of risk prediction updates from commercial genome-wide scans. Genetics in Medicine, 2009. 11(8): 588-594.
Vrecar I, et al. Direct-to-consumer genetic testing in Slovenia: availability, ethical dilemmas and legislation. Biochemia medica, 2015. 25(1): 84-89.
Gollust SE, Hull SC, Wilfond BS. Limitations of direct-to-consumer advertising for clinical genetic testing. Jama, 2002. 288(14): 1762-1767.
McGuire AL and Burke W. An unwelcome side effect of direct-to-consumer personal genome testing: raiding the medical commons. Jama, 2008. 300(22): 2669-2671.
Robertson AS. Taking responsibility: regulations and protections in direct-to-consumer genetic testing. Berkeley Technology Law Journal, 2009. 24(1): 213-243.
Saukko P. State of play in direct-to-consumer genetic testing for lifestyle-related diseases: market, marketing content, user experiences and regulation. Proceedings of the Nutrition Society, 2013. 72(01): 53-60.
Most read articles by the same author(s)