Effects of concomitant selenium and vitamin E administration on thyroid hormone metabolism in broilers

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Published: Jan 29, 2018
DOI: https://doi.org/10.12681/jhvms.15490
Keywords:
Broiler glutathione peroxidase selenium type I iodothyronine deiodinase vitamin E
A. C. PAPPAS
Department of Nutritional Physiology and Feeding, Faculty of Animal Science and Aquaculture, School of Agriculture Engineering and Environmental Sciences, Agricultural University of Athens
B. M. KOTSAMPASI
Animal Research Institute, Hellenic Agricultural Organization (HAO) – DEMETER
K. KALAMARAS
Department of Anatomy and Physiology of Domestic Animals, Faculty of Animal Science and Aquaculture, School of Agriculture Engineering and Environmental Sciences, Agricultural University of Athens
K. FEGEROS
Department of Nutritional Physiology and Feeding, Faculty of Animal Science and Aquaculture, School of Agriculture Engineering and Environmental Sciences, Agricultural University of Athens
G. ZERVAS
Department of Nutritional Physiology and Feeding, Faculty of Animal Science and Aquaculture, School of Agriculture Engineering and Environmental Sciences, Agricultural University of Athens
D. KALOGIANNIS
Department of Anatomy and Physiology of Domestic Animals, Faculty of Animal Science and Aquaculture, School of Agriculture Engineering and Environmental Sciences, Agricultural University of Athens
S. E. CHADIO
Department of Anatomy and Physiology of Domestic Animals, Faculty of Animal Science and Aquaculture, School of Agriculture Engineering and Environmental Sciences, Agricultural University of Athens
Abstract

A total of 400, as hatched, broilers were used to investigate the effect of selenium (Se) and vitamin E supplementation on thyroid hormones metabolism. There were 5 replicates of 4 dietary treatments namely: control (C), a soybean meal maize basal diet with adequate Se and vitamin E (0.3 mg Se per kg diet and 80 mg vitamin E per kg diet), control diet with Se added (Se+, with an additional 1 mg of Se per kg of diet), control diet with vitamin E added (E+, with an additional 350 mg of vitamin E per kg of diet) and Se+E+ (with additional 1 mg of Se and 350 mg of vitamin E per kg of diet). Diets were isonitrogenous and isocaloric. Zinc L-selenomethionine complex was used to increase Se content and dl-α-tocopheryl acetate to increase vitamin E content. The experiment lasted 42 days. Plasma Se concentration increased in Se+ groups, while whole blood glutathione peroxidase (GPx) activity increased in Se+, E+ and Se+E+ groups compared to control. Hepatic type I iodothyronine deiodinase (ID-I) and thyroid hormone concentrations were unaffected by any dietary treatment. It is concluded that supplementation with Se or vitamin Ε alone or in combination above animal’s requirements does not affect thyroid hormone metabolism and liver ID-I activity under the conditions examined.

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