Granulosa Cell Tumor In A Spayed Young Queen

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DOI: https://doi.org/10.12681/jhvms.18022
Keywords:
Granulosa cell tumor IGF-1 estrogen ovary queen
Z. GÜNAY UÇMAK
Department of Obstetrics and Gynaecology, Faculty of Veterinary Medicine
M. UÇMAK
Department of Obstetrics and Gynaecology, Faculty of Veterinary Medicine, Istanbul University
Ç. TEK
Department of Obstetrics and Gynaecology, Faculty of Veterinary Medicine, Istanbul University
L. KOENHEMSI
Department of Internal Medicine, Faculty of Veterinary Medicine, Istanbul University
Ö. ERDOGAN BAMAÇ
Department of Pathology, Faculty of Veterinary Medicine, Istanbul University
A. GÜREL
Department of Pathology, Faculty of Veterinary Medicine, Istanbul University
E. YILDAR
Institute of Health Sciences, Istanbul University
Abstract

A four years old cat was presented to Clinic of Obstetrics and Gynaecology with complaints of weakness, inappetency, vomiting and estrus signs although it was spayed. Blood tests, radiography and ultrasonography revealed abdominal mass and uterine stump which were then removed surgically. Multilobular mass was defined as solid granulosa cell tumor (GCT). Increase of estrogen (E2) and insulin-like growth factor-1 (IGF-1) values were detected on the 10th postoperative day. On the 40th postoperative day, the cat was brought to Internal Medicine Clinic with the complaints of weakness, inappetency and cachexia. Anemia, leucocytosis, uremia, hyperglycemia, sensitiveness and pain in the right abdomen were determined. A tumor was detected in the liver by radiography and ultrasonography and was suspected to be GCT metastasis. Despite medical therapy, the cat died after four months. In conclusion; retained ovarian tissue after erroneous ovariohysterectomy may cause, regular estrus signs and GCT development. Even if GCTs are removed by surgical approach, they have metastatic potential that deteriorates the prognosis. Evaluating IGF-1 and E2 in the short postoperative term are beneficial for determining the metastatic potential of GCTs.

Article Details
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  • Case Report
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