Investigation of the Epidemiology of Small Ruminant Lentivirus Infections southeast part of the Marmara region of Turkey

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Published: Jan 25, 2023
DOI: https://doi.org/10.12681/jhvms.29095
Keywords:
ELISA PCR sheep lentivirus Turkey
A Sait
Pendik Veterinary Control Institute, Viral Diagnostic Laboratory, 34890 Pendik, Istanbul, Turkey
OB Ince
Pamukkale UniversityAnimal Breeding and Genetic Research and ImplementationCenter
https://orcid.org/0000-0001-8302-9607
Abstract

Small ruminant lentiviruses (SRLVs) are viral pathogens that are common in goats and sheep, affect production, and cause significant economic losses in small ruminant breeding. Caprine arthritis encephalitis virus (CAEV) and Maedi-Visna virus (MVV) are prototypes of SRLVs. Both of them affect animal health and welfare in sheep and goats and cause progressive and persistent infections in the small ruminant industry. The present study aimed to reveal the epidemiological status of lentivirus infection in the sheep region in Yalova province located in the southeast part of the Marmara region and determine the circulating genotypes by conducting the sequence analysis of the samples detected positive by a molecular method and molecular characterization of the detected field strains. To that end, 231 sheep blood samples were used between May 2016 and April 2018. Based on sampling results of the PCR test and ELISA tests, 5.62% (13/231) and 5.19% (12/231) positivity rates were found in sheep, respectively. According to the ELISA test results, a significant difference was found in terms of age groups (6 months -1 age, 1-3 age, >3 age) (χ2: 6.01; p=0.04). Furthermore, the sequence analysis of the gag gene region detected the existence of the A genotype of small ruminant lentiviruses in sheep. The data obtained from the study revealed a low seroprevalence course of SRLV infection in the study area in the absence of a systematic disease control program.

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Author Biographies
A Sait, Pendik Veterinary Control Institute, Viral Diagnostic Laboratory, 34890 Pendik, Istanbul, Turkey

Pendik Veteriner Kontrol Enstitüsü, Viral Teşhis Laboratuvarı, 34890 Pendik, İstanbul, Türkiye

OB Ince, Pamukkale UniversityAnimal Breeding and Genetic Research and ImplementationCenter

Dr.Ömer Barış İNCE
Pamukkale Üniversitesi
Hayvan Yetiştiriciliği ve Genetik Araştırma ve Uygulama Merkezi
Kınıklı Kampüsü Pamukkale/Denizli
Telefon: +90 258 296 7576 Faks : +90 (258) 296 23 38

Mobil:+905052216985

References
Albayrak H, Yazici Z, Okur-Gumusova S, Ozan E (2012) Maedivisna virus infection in Karayaka and Amasya Herik breed sheep from provinces in northern Turkey. Trop Anim Health Prod, 44 (5): 939-941.
Alibaşoğlu M, Arda M, (1975) Koyunlarda pulmoner adenomatozis’inin Türkiye’de durumu ile patoloji ve etiyolojisinin araştırılması. Tübitak-VHAG yay, 273 (4): 111.
Alvarez V, Arranz J, Daltabuit-Test M et al. (2005) Relative contribution of colostrum from Maedi-Visna virus (MVV) infected ewes to MVV-seroprevalence in lambs. Res Vet Sci 78 (3): 237-243.
Ameen PSM, Karapınar Z (2018) Seroprevalence of Visna-Maedi Virus (VMV) and Border Disease Virus (BDV) in Van province and around. Arq Bras Med Vet Zootec, 70: 04.
Andrésdóttir V (2018) Maedi-visna virus as a model for HIV, Icel Agric Sci, 31:23-47.
Arık C, Acar A, Gür S (2015) A clinical and serological investigation for Maedi-Visna Virus (MVV) infection in Afyonkarahisar province. Kocatepe Vet J, 8 (1): 39-44.
Brinkhof JMA, Houwers DJ, Moll L, Dercksen D, van Maanen C (2010) Diagnostic performance of ELISA and PCR in identifying SRLV-infected sheep and goats using serum, plasma and milk samples and in early detection of infection in dairy flocks through bulk milk testing. Vet Microbiol, 142 (3-4): 193-198.
Bolea R, Monleon E, Carrasco L, Vargas A, de Andrés D, Amorena B, Badiola JJ, Luján L (2006) Maedi-Visna virus infection of ovine mammary epithelial cells. Vet Res, 37 (1): 133-144.
Burgu İ, Toker A, Akça Y, Alkan F., Yazıcı Z, Özkul A (1990) Türkiye’de Visna- Maedi enfeksiyonunun serolojik olarak araştırılması. AÜ Vet Fak Derg, 37 (3): 538-553.
Çelik, ÖY, Akgül G, İrak K (2018) Investigation of seroprevalence of Maedi-Visna and Caprine Arthritis Encephalitis in sheep and goats in Siirt province. Atatürk Üni Vet Bil Derg, 13 (3): 274-277.
Daltabuit-Test, M, Juste, RA, Berriatua, E (2008) Development of a PCR test to detect cell-free and integrated and Maedi-Visna Vırus (MVV) and it’s use to investigate colostral infection in lambs. An Vet. Murcia, 22:57-66.
Dean, A.G., Sullivan, K.M., Soe, M.M.,2013. OpenEpi: Open source epidemiologic statistics for public health, http://www.OpenEpi.com, updated 2013/04/06, [Accessed 03 Dec 2021]
De Andrés D, Klein D, Watt NJ, Berriatua E, Torsteinsdottir S, Blacklaws BA, Harkiss G D (2005) Diagnostic tests for small ruminant lentiviruses. Vet Microbiol, 107 (1-2): 49-62.
Doğan F, Ataseven VS, Dağalp SB, Ergün Y (2021) Doğu Akdeniz bölgesinde küçük ruminant lentivirus enfeksiyonlarının serolojik ve moleküler yöntemlerle araştırılması Eurasian J Vet Sci, 37 (3): 193-201.
Echeverría I, De Miguel R, De Pablo-Maiso L, Glaria I, Benito AA, De Blas I, De Andrés D, Luján L, Reina R (2020) Multi-platform detection of small ruminant lentivirus antibodies and provirus as biomarkers of production losses. Front Vet Sci, 7: 182.
Gayo E, Polledo L, Magalde A, Balseiro A, García Iglesias MJ, Martínez CP, Preziuso S, Rossi G, Marín JFG (2019) Characterization of minimal lesions related to the presence of visna/maedi virus in the mammary gland and milk of dairy sheep. BMC Vet Res, 15: 109.
Gezer T, Akyüz E, Gökçe G (2021) Investigation of Seroprevalence of Maedi-Visna Infection in some sheep flocks in Kars province, Turkey. Dicle Üniv Vet Fak Derg, 14 (1): 48-51.
Gomez-Lucia E, Barquero N, Domenech A (2018) Maedi-Visna virus: current perspectives. Vet Med (Auckl). 9: 11-21.
Gürçay M, Parmaksız A, (2013) An investigation of Visna-Maedi virus infection in Şanlıurfa Province, Southeast Anatolia, Turkey. AVKAE Derg, 3 (1): 46-50.
Heaton MP, Clawson ML, Chitko-Mckown CG, Leymaster KA, Smith TPL, Harhay GP, White SN, Herrmann-Hoesing LM, Mousel MR, Lewis GS, Kalbfleisch TS, Keen J E, Laegreid WW (2012) Reduced lentivirus susceptibility in sheep with TMEM154 mutations. PLoS Genet. 8: e1002467.
Hüttner K, Seelmann M, Feldhusen F (2010) Prevalence and risk factors for Maedi-Visna in sheep farms in Mecklenburg-Western-Pomerania. Berl Münch Tierärztl, 123: 463-467.
Junkuszewa A, Dudko P, Bojar W, Olech M, Osiński Z, Gruszecki TM, Kania MG, Kuźmak J, Czerski G (2016) Risk factors associated with small ruminant lentivirus infection in eastern Poland sheep flocks. Prev Vet Med, 127: 44-49.
Kalogianni AI, Bossis I, Ekateriniadou LV, Gelasakis AI (2020) Etiology, epizootiology and control of Maedi-Visna in dairy sheep: A review. Animals, 10: 616.
Karaoğlu T, Alkan F, Burgu I, (2003) Küçük aile işletmelerindeki koyunlarda Maedi-Visna enfeksiyonunun seroprevalansı, AÜ Vet Fak Derg, 50(2): 123-126.
Michiels R, Van Mael E, Quinet C, Welby S, Cay AB, de Regge N (2018) Seroprevalence and risk factors related to small ruminant lentivirus infections in Belgian sheep and goats. Prev Vet Med, 151: 13-20.
Muz D, Oguzoglu TC, Rosati S, Reina R, Bertolotti L, Burgu I (2013) First molecular characterization of Visna/Maedi viruses from naturally infected sheep in Turkey. Arch Virol,158 (3): 559-570.
Norouzi B, Razavizade A, Azizzadeh M, Mayameei A, Mashhadiv S (2015) Serological study of small ruminant lentiviruses in sheep population of Khorasan-e-Razawi province in Iran. Vet Res Forum, 6(3): 245-249.
OIE (2017). Terrestrial Manual. Chapter 2.7.2/3. Caprine arthritis- encephalitis & Maedi-Visna. https://www.oie.int/fileadmin/Home/eng/Health_standards/tahm/2.07.02-03_CAE_MV.pdf[Accessed 03 Dec 2021]
Olech M, Ropka-Molik K, Szmatoła T, Piórkowska K, Kuźmak J (2021) Transcriptome analysis for genes associated with small ruminant lentiviruses infection in goats of Carpathian breed. Viruses, 13(10):2054.
Peterhans E, Greenland T, Badiola J, Harkiss G, Bertoni G, Amorena B, Eliaszewicz M, Juste RA, Krassnig R, Lafont J P, Lenihan P, Pétursson G, Pritchard G, Thorley J, Vitu C, Mornex J F, Pépin M (2004) Routes of transmission and consequences of small ruminant lentiviruses (SRLVs) infection and eradication schemes. Vet Res, 35(3): 257-274.
R Core Team (2018) R: A language and environment for statistical computing. R Foundation for Statistical Computing, Vienna, Austria. http://www.R-project.org. [accessed 01 May 2018]
Ramírez H, Echeverría I, Benito AA, Glaria I, Benavides J, Pérez V, de Andrés D, Reina R (2021) Accurate diagnosis of small ruminant lentivirus infection is needed for selection of resistant sheep through TMEM154 E35K Genotyping. Pathogens (Basel, Switzerland), 10(1): 83.
Reina R, Berriatua E, Lujan L, Juste R, Sánchez A, de Andrés D, Amorena B (2009) Prevention strategies against small ruminant lentiviruses: An update. Vet J, 182 81): 31-37.
Reina R, Mora MI, Glaria I, García I, Solano C, Luján L, Badiola JJ, Contreras A, Berriatua E, Juste R, Mamoun RZ, Rolland M, Amorena B, de Andrés D (2006) Moleculer characterisation and phylogenetic study of Maedi Visna and Caprine Arthritis Encephalitis viral sequences in sheep and goats from Spain. Virus Res, 121 (2): 189-198.
Scheer-Czechowski P, Vogt, HR, Tontis A, Peterhans E, Zanoni R (2000) Pilotprojekt zur Sanierung der Maedi-Visna bei Walliser Schwarznasenschafen (Pilot project for eradicating maedi-visna in Walliser blacknose sheep). Schweiz Arch Tierheilkd, 142: 155-164.
Schreuder BEC, Yonguç AD, Girgin H, Akçora A (1988) Antibodies to Maedi-Visna in indigenous sheep in Eastern Turkey. Etlik Vet Mikrobiyol Derg, 6 (3): 47-53.
Shuaib M, Green C, Rashid M, Duizer G, Whiting TL (2010) Herd risk factors associated with sero-prevalence of Maedi-Visna in the Manitoba sheep population. Can Vet J, 51 (4): 385-390.
Stonos N, Wootton SK, Karrow, N (2014) Immunogenetics of small ruminant lentiviral infections. Viruses, 6 (8): 3311-3333.
Tavella A, Bettini A, Ceol M, Zambotto P, Stifter E, Kusstatscher N, Lombardi R, Nardeli S, Beato MS, Capello K, Bertoni G (2018) Achievements of an eradication programme against caprine arthritis encephalitis virus in South Tyrol, Italy. Vet Rec, 182 (2): 51.
Tefera N, Mulate B (2016) Seroprevalence of Maedi-Visna in sheep in selected districts of Amhara region, Ethiopia. Bull Anim Health Prod Afr, 64(4): 423-430.
Un H, Ozgünlük I, Cabalar M (2018) Şanlıurfa Yöresinde Maedi- Visna Virus (MVV) enfeksiyonunun serolojik olarak araştırılması. Harran Üniv Vet Fak Derg, 7 (2): 144-148.
Yavru S, Simsek A, Bulut O, Kale M (2012) Serological investigation of Maedi-Visna Virus infection in sheep in Konya region. Eurasian J Vet Sci, (28) 3: 142-148.
Yılmaz H, Gürel A, Turan N, Bilal T, Kuscu B, Dawson MM, Morgan KL (2002) Abottoir study of Maedi-Visna virus infection in Turkey. Vet Rec, 151 (12): 358-360.
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