Application of metagenomics in bacterial resistance in cattle production

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Published: May 15, 2026
DOI: https://doi.org/10.12681/jhvms.41197
Keywords:
metagenomics cattle bacteria drug resistance application
X Zhang
Inner Mongolia Minzu University, College of Animal Science and Technology, Tongliao 028000, Inner Mongolia, China.
J Li
Tongliao Kulun Banner Animal Disease Prevention and Control Center, Tongliao 028000, Inner Mongolia, China
Y Chen
Inner Mongolia Tongliao Agricultural and Animal Husbandry Development Centre, Tongliao 028042, China
W Jia
Tongliao Academy of Agricultural and Animal Husbandry Sciences, Tongliao 028000, Inner Mongolia, China
Z Jia
Inner Mongolia Minzu University, College of Animal Science and Technology, Tongliao 028000, Inner Mongolia, China
J Cui
Inner Mongolia Minzu University, College of Animal Science and Technology, Tongliao 028000, Inner Mongolia, China
Y Zhang
Inner Mongolia Minzu University, College of Animal Science and Technology, Tongliao 028000, Inner Mongolia, China
H Xiong
Inner Mongolia Minzu University, College of Animal Science and Technology, Tongliao 028000, Inner Mongolia, China
X Wang
Inner Mongolia Minzu University, College of Animal Science and Technology, Tongliao 028000, Inner Mongolia, China
Abstract

Microorganisms are widely found in nature, mostly in soil and water. For ruminant animals, microorganisms make up a high percentage of their rumen. In recent years, the inappropriate use of antibiotics has led to a gradual increase in the resistance of bacteria commonly found in the bovine digestive tract which can be transmitted between humans, animals, and the environment. With the rapid development of molecular biology technology, Metagenomics technology can be more efficient, fast, and accurate in detecting resistance genes in samples and discovering novel resistance genes, making the study of bovine bacterial resistance more convenient and thorough. This paper mainly reviews bacterial resistance in cattle and the application of Metagenomics technology in this study. It intends to provide a theoretical reference for understanding the clinical application of metagenomics in bovine production to slow the emergence of bacterial resistance.

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