Clinical and epidemiological profiles and outcome of non-traumatic myelopathies in dogs


Published: Apr 18, 2023
Updated: 2023-04-18
Versions:
2023-04-18 (2)
Keywords:
degenerative disc disease epidemiological profile dog non-traumatic myelopathies outcome
RD Baka
https://orcid.org/0000-0002-1120-4522
S Balla
GM Kazakos
https://orcid.org/0000-0001-6678-2824
MN Patsikas
ZS Polizopoulou
https://orcid.org/0000-0003-4039-2398
Abstract

Myelopathies, the disorders affecting the spinal cord, are classified into traumatic or non-traumatic. In dogs, intervertebral disc disease (IVD) is the most common cause of spinal pain and neurological deficits. The aim of the current study is to present the prevalence, clinical presentation, diagnosis and outcome of non-traumatic myelopathies of various etiologies, in dogs. This was a retrospective study in dogs. The inclusion criteria for the dog population included complete clinical records of the cases (physical, neurological examination, clinicopathological and/or diagnostic imaging), therapy, outcome and re-examinations. A total of 618 dogs were included in the study with a mean age of 6 years and a mean body weight of 12Kg. The neurological deficits appeared acutely in 346 dogs (56%).Paraplegia (201/618, 32.5%), paraparesis (144/618, 23.3%) were the most frequent neurological deficits, followed by spinal pain (61/618, 9.9%). In the majority of cases the lesions (374/618, 60.5%) were localized in the thoracolumbar spinal cord segments. Degenerative disc disease was the predominant diagnosis in the study population (212 dogs, 62.5%), followed by neoplasia (10%), congenital anomalies (6.2%), myelitis (5.9%) and, less frequently, discospondylitis (4.1%), caudal cervical spondylomyelopathy (3.8%) and meningitis (3%). There were few cases with extradural synovial cysts (2.1%), congenital myelopathies (1.2%), Chiari like malformation (0.9%). Regarding outcome, 476/618 (77%) dogs were alive at the end of the study. From the 476 dogs that were still alive, 278/476 dogs (58.4%) improved neurologically, 120/476 dogs (25.2%) were neurologically stable, 22/476 dogs (4.6%) deteriorated. Degenerative disc disease was the most common diagnosis in dogs admitted with paraparesis/ paraplegia. Myelography could diagnose secondary spinal compression caused by disc protrusion/ extrusion or any other cause. Corticosteroids and non-steroidal anti-inflammatory drugs (NSAID) were used commonly by the referring veterinarian in case a compressive myelopathy was suspected. Prognosis in dogs with degenerative disc disease type II is favorable when therapy was started soon after the clinical sign’s onset and the deep pain sensation was intact.

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References
Bagley RS (2010) Spinal neoplasms in small animals. Vet Clin North Am Small AnimPract 40: 915-927.
Bell A, Helm J, Reid J (2014) Veterinarians’ attitudes to chronic pain in dogs. Vet Rec 175 (17): 428. DOI: 10.1136/vr.102352.
Besalti O, Caliskan M, Can P, Vural SA, Algin O, Ahlat O (2016) Imaging and surgical outcomes of spinal tumors in 18 dogs and one cat. J Vet Sci 17 (2): 225-234.
Da Costa RC, Samii VF (2010) Advanced imaging of the spine in small animals. Vet Clin Small Anim 40: 765-790.
Da Costa RC, Cook LB (2016) Cystic abnormalities of the spinal cord and vertebral column. Vet Clin Small Anim 46: 277-293.
Davies JV, Sharp NJH (1983) A comparison of conservative treatment and fenestration for thoracolumbar intervertebral disc disease in the dog. J Small AnimPract 24:721-729.
Dennison SE, Drees R, Rylander H, Yandell BS, Milovancev M, Pettigrew R, Schwarz T (2010) Evaluation of different computed tomography techniques and myelography for the diagnosis of acute canine myelopathy. Vet Radiol Ultrasound 51(3): 254-258.
Dewey CW (2008) Myelopathies: Disorders of the spinal cord. In: A practical guide to canine and feline neurology. 2nded, Wiley-Blackwell, Ames pp 323-388.
Dewey CW, Bailey KS (2008) Signalment, history, and the differential diagnosis: the firstconsideration. In: A practical guide to canine and felineneurology. 2nded, Wiley-Blackwell, Ames pp 4–14. (b)
Dorn M, Seath IJ (2018) Neuter status as a risk factor for canine intervertebral disc herniation (IVDH) in dachshunds: a retrospective cohort study. Canine Genet Epidemiol 15 (5): 11.
Fletcher DJ, Dewey CW (2003) Spinal trauma management. In: Practical guide to canine and feline neurology. Iowa State University Press, Ames pp405-417.
Hara Y, Tagawa M, Ejima H, Orima H, Fujita M (1994) Usefulness of computed tomography after myelography for surgery on dogs with cervical intervertebral disc protrusion. J Vet Med Sci 56 (4): 791-794.
Heyman SJ, Diefenerfer DL, Goldschmidt MH, Newton CD (1992) Canine axial skeletalosteosarcoma: a retrospective study of 116 cases (1986 to 1989). Vet Surg 21: 304-310.
Israel SK, Levine JM, Kerwin SC, Levine GJ, Fosgate GT (2009) The relative sensitivity of computed tomography and myelography for identification of thoracolumbar intervertebral disc herniations in dogs. Vet Radiol Ultrasound 50 (3): 247-252.
Lawrie ML, Platt SR, Garosi LS (2014) Extramedullary spinal cysts in dogs. Vet Surg 43 (6): 650-662.
Levine JM, Levine GJ, Johnson SI, Kerwin SC, Hettlich BF, Fosgate GT (2007) Evaluation of the success of medical management for presumptive thoracolumbar intervertebral disc herniation in dogs. Vet Surg 36: 482-491.
Liebel FX, Rossmeisl JH Jr, Lanz OI, Robertson JL (2011) Canine spinal nephroblastoma: long-term outcome associated with treatment of 10 cases (1996-2009). Vet Surg 40: 244-252.
Lorenz MD, Kornegay JN (2004) Pelvic limb paresis, paralysis, or ataxia. In: Handbook of Veterinary Neurology, 4thed, Saunders, St. Louis pp 131-174.
Mathews KA (2008) Neuropathic pain in dogs and cats: if only they could tell us if they hurt. Vet Clinics North Am Small Anim Pract 38: 1365-1414.
Morgan PW, Parent JM, Holmberg DL (1993) Cervical pain secondary to intervertebral disc disease in dogs: radiographic findings and surgical implications. Prog Vet Neurol 4: 76-80.
New PW, Sundararajan V (2008) Incidence of non-traumatic spinal cord injury in Victoria,Australia: a population-based study and literature review. Spinal Cord 46:406–411.
New PW, Farry A, Baxter D, Noonan VK (2013) Prevalence of non-traumatic spinal cord injury in Victoria, Australia. Spinal Cord 51: 99-102.
Newcomb B, Arble J, Rochat M, Pechman R, Payton M (2012) Comparison of computed tomography and myelography to a reference standard of computed tomographic myelography for evaluation of dogs with intervertebral disc disease. Vet Surg 41 (2): 207-214.
Noonan VK, Fingas M, Farry A, Baxter D, Singh A, Fehlings MG, Dvorak MF (2012) The incidenceand prevalence of SCI in Canada: a national perspective. Neuroepidemiology 38: 219–226.
Olby N, Harris T, Burr J, Munna K, Sharp N, Keene B (2004) Recovery of pelvic limb function in dogs following acute intervertebral disc herniations. J Neurotrauma 21: 49-59.
Pancotto TE, RossneislJHJr, Zimmerman K, Robertson JL, Were SR (2013) Intramedullary spinal cord neoplasia in 53 dogs (1990-2010): distribution, clinicopathological characteristics, and clinical behavior. J Vet Intern Med 27: 1500-1508.
Park E, White GA, Tieber LM (2012) Mechanisms of injury and emergency care of acute spinal cord injury in dogs and cats. J Vet Emerg Crit Care 22(2): 160-178.
Rosenblatt AJ, Bottema CD, Hill PB (2014) Radiographic scoring for intervertebral disc calcification in the Dachshund. Vet J 200: 355-361.
Rusbridge C, Jeffery ND (2008) Pathophysiology and treatment of neuropathic pain associated with syringomyelia. Vet J 175: 164-172.
Sukhiani HR, Parent JM, Atilola MA, Holmberg DL (1996) Intervertebral disc disease in dogs with signs of back pain alone: 25 cases (1986-1993). J Am Vet Med Assoc 209: 1275-1279.
Vitale C, Coates J (2007) Acute spinal cord injury. Stand care: EmergCrit Care Med 9.7: 1-11.
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