Evaluation of Retinol, Cholecalciferol, α-Tocopherol and Phylloquinone levels in naturally infected calves with eimeriosis
Περίληψη
The aim of this study was to evaluate whether serum vitamin A (retinol), vitamin D (cholecalciferol), vitamin E (α-tocopherol), and vitamin K (phylloquinone) levels changed in naturally infected calves with coccidiosis. The study was conducted on a total of 70 calves, 55 with coccidiosis and 15 healthy (control) calves of different races, sexes, and ages ranging from 26 to 60 days, with complaints of bloody diarrhea, weight loss and tenesmus. As a result of statistical analysis; serum vitamin A, D, E, and K concentrations of calves with coccidiosis were significantly lower than the control group (P<0.001). In the correlation between parameters in calves with coccidiosis; in Pearson correlation for calves with coccidiosis, between serum retinol (vitamin A), cholecalciferol (vitamin D), α-tocopherol (vitamin E), and phylloquinone (vitamin K) levels respectively; Positive correlation was detected at the levels of 0.996, 0.996, and 0.990. As a result; significant decreases were detected in serum retinol (vitamin A), cholecalciferol (vitamin D), α-tocopherol (vitamin E), and phylloquinone (vitamin K) levels concentrations of calves with coccidiosis. It can be thought that the use of preparations containing vitamin A, D, E, and K may be beneficial in addition to the routine treatments in cases of coccidiosis or other diarrhea.
Λεπτομέρειες άρθρου
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Denizhan, V., Kozat, S., & Ekin, S. (2025). Evaluation of Retinol, Cholecalciferol, α-Tocopherol and Phylloquinone levels in naturally infected calves with eimeriosis. Περιοδικό της Ελληνικής Κτηνιατρικής Εταιρείας, 76(1), 8555–8562. https://doi.org/10.12681/jhvms.34707
- Τεύχος
- Τόμ. 76 Αρ. 1 (2025)
- Ενότητα
- Research Articles
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Αναφορές
Adams JS, Hewison M. (2010). Update in vitamin D. J Clin Endocrinol
Metab 95: 471-8.
Ahmed WM, Hassan SE. (2007). Applied studies on eimeriosis in growing
buffalo-calves with special reference to oxidant/antioxidant
status. World J Zool, 2(2), 40-48.
Al-Habsi K, Ali H, Al-Kharousi K, Elshafie EI, Al-Busaidi R, Muhiuddin
A, Johnson EH. (2020). Vitamin B12 deficiency in newly weaned
goat kids associated with clinical infection with Eimeria arloingi. Revista
Brasileira de Parasitologia Veterinária, 29, 1-9.
Alnassan AA, Kotsch M, Shehata AA, Krüger M, Daugschies A., Bangoura
B. ( 2014). Necrotic enteritis in chickens: development of a
straightforward disease model system. Vet Rec 174:555.
Arslan MÖ, Kırmızıgül AH, Parmaksızoğlu N, Erkılıç EE. (2015). Eimeria
zuernii ile doğal enfekte buzağılarda ilk kış coccidiosisi olgusu.
Atatürk Üniversitesi Veteriner Bilimleri Dergisi, 10(3), 193-197.
Battersby AJB, Kampmann S. (2012). Vitamin D in early childhood and the effect on immunity to Mycobacterium tuberculosis. Clin. Dev. Immunol.
:430972.
Baydar E, Özübek S. (2012). A case of clinical coccidiosis in a Holstein
cow. Sağlık Bilimleri Veteriner Dergisi, Fırat Üniversitesi, 26(2), 111-
Bucak IH, Ozturk AB, Almis H, Cevik MÖ, Tekin M, Konca Ç, Bulbul
M. (2016). Is there a relationship between low vitamin D and rotaviral
diarrhea?. Pediatrics International, 58(4), 270-273.
Cazarotto CJ, Boito JP, Gebert RR, Reis JH, Machado G, Bottari, NB, Da
Silva A.S. (2018). Metaphylactic effect of minerals on immunological
and antioxidant responses, weight gain and minimization of coccidiosis
of newborn lambs. Research in Veterinary Science, 121, 46-52.
Daugschies A, Najdrowski M. (2005). Eimeriosis in cattle: current understanding.
Journal of Veterinary Medicine, Series B, 52(10), 417-427.
Davoodi Z., Kojouri G.A. 2015. Mineral, metalloid, and heavy metal status
in sheep with clinical coccidiosis. Comparative Clinical Pathology,
(2), 259-262.
Denizhan V, Kozat S. 2022. Evaluation of the concentrations of some
trace elements (Fe, Cu, Se, Zn and Co) in calves naturally infected
with coccidiosis. J. Elem. 27(1): 155-164.
Eğlenti N., Kozat S., Denizhan V. 2020. Investigation of immunoglobulin
(IgE, IgA, IgG, IgM) concentrations in calves naturally infected with
coccidiosis. Journal of Istanbul Veterinary Sciences, 4(1), 1-7.
Ferland G, Sadowski JA. Vitamin K1 (phylloquinone) content of edible
oils: effects of heating and light exposure. J Agricult Food
;40(1002):1869-73.
Finch JM, Turner RJ. (1996). Effects of selenium and vitamin E on the
immune response of domestic animals. Res Vet Sci 60: 97-106.
Gazioğlu A, Gül Y. (2002). Sağlıklı ve ishalli neonatal buzağılarda karaciğer
dokusu ve kan serumu beta karoten ve vitamin A miktarları
ile serum protein fraksiyonları üzerine araştırmalar: I. Kan serumu
ve karaciğer dokusu vitamin A ve β-karoten düzeyleri. FÜ Sağ Bil
Derg 16(2):145-8.
Goodier GE, Williams JC, O’Reilly KL, Snider TG, Stanley CC, Dolejsiova
AH, Williams, CC. (2012). Effects of supplemental vitamin E
and lasaocid on growth and immune responses of calves challenged
with Eimeria bovis. The Professional Animal Scientist, 28(1), 97-107.
Gül Y. İssi M. (1989). Elazığ çevresinde halka ait sığırların kan plazmasında
vitamin-A ve karoten miktarlarının döl verimi ve buzağılarının
sağlıkları üzerine etkilerinin araştırılması. FÜ Sağ Bil
Derg 1(2/A):103-12.
Huang Z, Rose AH, Hoffman NPR. (2012). The role of selenium in inflammation
and immunity: from molecular mechanisms to therapeutic
opportunities. Antioxidants & Redox Signaling, 16(7), 705-743.
Issi M, Gül Y, Polat PF. (2016). Selenyum ve Vitamin E Yetmezliği. Vet
Sci Intern Med-Special Topics 2(2):25-31.
Jin, L, Yan S, Shi B, Bao H, Gong J, Guo X., Li J. (2014). Effects of vitamin
A on the milk performance, antioxidant functions and immune
functions of dairy cows. Animal Feed Science and Technology, 192,
-23.
Kaya A, Kozat S, Özbek M. (2016). C ve K Vitamini Yetmezlikleri. J Vet
Sci Intern Med-Special Topics 2(2), 56-63
Kleczkowski M., Klucinski, W, Sikora, J, Zdanowicz, M. (2004). Role of
antioxidants in the protection against oxidative stress in cattle-trace
elements andenzymatic mechanisms. Pol. J. Vet. Sci. 7, 233-240.
Kozat, S. (2006). Geviş getiren hayvanlarda İz elementlerin önemi, gerekliliği
ve noksanlıkların etkileri. Van Yüzüncü Yıl Üniversitesi, Sağlık
Bilimleri Dergisi 9 (2): 58-67.
Kozat, S. (2019). Yenidoğan buzağılarda kolostrum yönetiminin önemi.
Atatürk Üniversitesi Veteriner Bilimleri Dergisi, 14(3), 343-353.
Ma, XM, Yang ZB, Yang WR, Song ML. (2005). Effect of different vitamin
A levels in diets on antioxidant ability of beef cattle (in Chinese).
Chin. J. Anim.Nutr. 17, 31-35.
Mamak N, Yıldız R. (2016). D Vitamini Yetmezliği. J Vet Sci Intern
Med-Special Topics 2(2), 54-69.
Mc Dowell LR. (2000). Vitamins in Animal Nutrition. 2nd ed. Iowa State
University Press/Ames; p.597-633.
McNally JD, Leis K., Matheson LA, Karuananyake C, Sankaran K,
Rosenberg AM. (2009). Vitamin D deficiency in young children with
severe acute lower respiratory tract infection. Pediatr. Pulmonol. 44:
-988.
Ocal N. (2016). Nervöz Koksidiyozis. J Vet Sci Intern Med-Special Topics,
(1): 63-7.
Palace, V.P., Khaper, N., Qin, Q., Singal, P.K. (1999). Antioxidant potentials
of vitamin A and carotenoids and their relevance to heart disease.
Free Radic. Biol.Med. 26, 746-761.
Pour HA, Sis NM, Razligh SN, Azar MS, Babazadeh MH, Maddah MT
(2011). Effects of vitamin E on ruminant animal. Annals of Biological
Research 2(4):244-51.
Radostits OM, Gay CC, Hinchcliff KW, Constable PD. (2008). Veterinary
Medicine. Textbook of the Diseases of Cattle, Horses, Sheep, Pigs
and Goats. 10th ed. Edinburgh, London, New York, Oxford, Philadelphia,
St Louis, Sydney, Toronto: Saunders Elsevier p.1-2156.
Raila J, Kawashima C, Sauerwein H, Hülsmann N, Knorr C, Myamoto A,
Schweigert, FJ. (2017). Validation of blood vitamin A concentration
in cattle: comparison of a new cow-side test (iCheck™ FLUORO)
with high-performance liquid chromatography (HPLC). BMC Veterinary
Research, 13(1), 1-6.
Rayman M P. (2012). Selenium and human health. Lancet 379:1256-1268
Reddy BS, Sivajothi S, Rayulu VC. (2015). Clinical coccidiosis in adult
cattle. Journal of Parasitic Diseases, 39(3), 557-559.
Reid D, Toole BJ, Knox S, Talwar D, Harten J, O’Reilly DS, Blackwell
S,Kinsella J, McMillan DC, Wallace AM (2011). The relation
between acute changes in the systemic inflammatory response and
plasma 25-hydroxyvitamin D concentrations after elective knee arthroplasty.
Am J Clin Nutr 93: 1006-1011.
Reis JP, von Muhlen D, Miller ER 3rd, Michos ED, Appel LJ (2009).
Vitamin D status and cardiometabolic risk factors in the United States
adolescent population. Pediatrics 124: 371-379.
Seemann E, Kurth T, Entzeroth R. (2012). Insight into the ultrastructural
organisation of sporulated oocysts of Eimeria nieschulzi (Coccidia,
Apicomplexa). Parasitology research, 111(5), 2143-2147.
Shehta A, El-Zahar H, Mansour A, Mustafa B, Shety, T. (2022). Clinical,
hematological and some biochemical alterations during diarrhea in
Friesian calves naturally infected with E. coli and Salmonella. Beni-
Suef University Journal of Basic and Applied Sciences, 11(1), 1-8.
Siluk D, Oliveira RV, Esther-Rodriguez-Rosas M, Ling S, Bos A, Ferrucci
L, Wainer IW. (2007). A validated liquid chromatography method
for the simultaneous determination of vitamins A and E in human
plasma. Journal of pharmaceutical and biomedical analysis, 44(4),
-1007.
Sloper K.S, Dourmashkin RR, Bird RB, Slavin G, Webster ADB. (1982).
Chronic malabsorption due to cryptosporidiosis in a child with immunoglobulin
deficiency. Gut, 23(1), 80-82.
Smith BP. (2009). Large Animal Internal Medicine. 4thed. St Louis, Missouri:
Mosby Elsevier; p.1-1821.
Su Q, Rowley KG, Balazs ND. (2002). Carotenoids: separation methods
applicable to biological samples. J Chromatogr B 781: 393-418.
Thomas HS. (1994). Coccidiosis in calves. The Cattleman, 81(5): 21-32.
Tufan A, Çam Y. (2009). Buzağı koksidiozisinde lipid peroksidasyon
düzeyi ve antioksidan enzim aktiviteleri, Sağlık Bilimleri Dergisi
(Journal of Health Sciences) 17(3) 131-136.
Turner RJ (1990). Finch JM. Immunological malfunctions associated with
low selenium-vitamin E diets in lambs. J Comp Pathol 102(1): 99-
Vermeer C. (1984). The vitamin K-dependent carboxylation reaction. Mol
Cel Biochem 61(1):17-35.
Wunderlich F, Al-Quraishy S, Steinbrenner H, Sies H, Dkhil M A. (2014).
Towards identifying novel anti-Eimeria agents: trace elements, vitamins,
and plant-based natural products. Parasitology Research,
(10), 3547-3556..
Yatoo MI, Saxena A, Deepa PM, Habeab BP, Devi S, Jatav RS, Dimri U.
(2013). Role of trace elements in animals: a review. Veterinary World,
(12), 963-967.
