Mast Cell Tumour and Mammary Gland Carcinoma Collision Tumour. Case report and literature review.

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Publicado: Oct 26, 2022
DOI: https://doi.org/10.12681/jhvms.27639
C Rifici
A Sfacteria
S di Giorgio
G Giambrone
G Marino
Associate Professor of TheriogenologyDirector of the School of Specialization of Physiopathology of reproduction in domestic animals, Department of Veterinary SciencesViale Giovanni Palatucci - 98168 Messina (Italy)
https://orcid.org/0000-0001-6519-406X
G Mazzullo
Resumen

Collision tumours are the coexistence, at the same venue, of distinct tumours not macroscopically distinguishable and consisting of two independent cell populations without histological admixture. In human medicine, collision tumours in different anatomical sites have been described. In the veterinary literature, few cases exist so far. A 12-year-old female Labrador with a mammary gland nodular lesion was presented for clinical examination. The nodule was surgically removed and underwent histological and immunohistochemical analysis. Histopathological examination revealed two distinct malignant tumours: a mammary gland carcinoma and a cutaneous mast cells tumour. To the author's knowledge, the paper reports the first case of a collision tumour composed of mammary gland neoplasia and mast cell tumour. The rising interest in collision tumours suggests widening their knowledge and setting up a multimodal approach that includes surgery and targeted therapy.

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Alawami, H. A., Al-Faraj, Z. H., Al Duhileb, M. A., AlOmran, H. A., & El Sayed, A. A. (2021). Unusual collision tumour with infiltrating ductal carcinoma and breast skin squamous cell carcinoma: A case report and literature review. Int J Surg Case Rep, 78, 167-171. https://doi.org/10.1016/j.ijscr.2020.12.010
Aponte-López, A., Fuentes-Pananá, E. M., Cortes-Muñoz, D., & Muñoz-Cruz, S. (2018). Mast Cell, the Neglected Member of the Tumour Microenvironment: Role in Breast Cancer. J Immunol Res, 2018, 2584243. https://doi.org/10.1155/2018/2584243
Brunetti, B., Beha, G., Benazzi, C., Bondin, V., De Tolla, L., & Sarli, G. (2014). CD117 expression influences proliferation but not survival in canine mammary tumours. J Comp Pathol, 151(2-3), 202-206. https://doi.org/10.1016/j.jcpa.2014.04.018
Bulte, C. A., Hoegler, K. M., & Khachemoune, A. (2020). Collision tumours: A review of their types, pathogenesis, and diagnostic challenges. Dermatol Ther, 33(6), e14236. https://doi.org/10.1111/dth.14236
Catteau, X., Dehou, M. F., Dargent, J. L., Hackx, M., & Noël, J. C. (2011). Chronic lymphocytic leukemia mimicking recurrent carcinoma of the breast: case report and review of the literature. Pathol Res Pract, 207(8), 514-517. https://doi.org/10.1016/j.prp.2011.05.007
Coca-Pelaz, A., Triantafyllou, A., Devaney, K. O., Rinaldo, A., Takes, R. P., & Ferlito, A. (2016). Collision tumours of the larynx: A critical review. Am J Otolaryngol, 37(4), 365-368. https://doi.org/10.1016/j.amjoto.2016.02.010
Dialani, V., Mani, K., & Johnson, N. B. (2013). Chronic lymphocytic leukemia involving the breast parenchyma, mimicker of invasive breast cancer: differentiation on breast MRI. Case Rep Med, 2013, 603614. https://doi.org/10.1155/2013/603614
Gattino, F., Maniscalco, L., Iussich, S., Biasato, I., Martano, M., Morello, E., . . . De Maria, R. (2018). PDGFR-α, PDGFR-β, VEGFR-2 and CD117 expression in canine mammary tumours and evaluation of the in vitro effects of toceranib phosphate in neoplastic mammary cell lines. Vet Rec, 183(7), 221. https://doi.org/10.1136/vr.104414
Jafarian, N., Kuppler, K., Rosa, M., Hoover, S., & Patel, B. (2015). Chronic Lymphocytic Leukemia and Invasive Ductal Carcinoma Presenting as a Collision Breast Tumour. Clin Breast Cancer, 15(4), e209-212. https://doi.org/10.1016/j.clbc.2015.02.001
Jakab, C., & Balka, G. (2012). First report of a malignant collision skin tumour with malignant melanoma and anaplastic sarcoma components in a dog. Acta Vet Hung, 60(2), 245-255. https://doi.org/10.1556/AVet.2012.021
Kiupel, M., Webster, J. D., Bailey, K. L., Best, S., DeLay, J., Detrisac, C. J., . . . Miller, R. (2011). Proposal of a 2-tier histologic grading system for canine cutaneous mast cell tumours to more accurately predict biological behavior. Vet Pathol, 48(1), 147-155. https://doi.org/10.1177/0300985810386469
Kiupel, M., Webster, J. D., Kaneene, J. B., Miller, R., & Yuzbasiyan-Gurkan, V. (2004). The use of KIT and tryptase expression patterns as prognostic tools for canine cutaneous mast cell tumours. Vet Pathol, 41(4), 371-377. https://doi.org/10.1354/vp.41-4-371
Kwok, E., Everingham, S., Zhang, S., Greer, P. A., Allingham, J. S., & Craig, A. W. (2012). FES kinase promotes mast cell recruitment to mammary tumours via the stem cell factor/KIT receptor signaling axis. Mol Cancer Res, 10(7), 881-891. https://doi.org/10.1158/1541-7786.MCR-12-0115
Lamprou, S., Glykas, I., Fragkoulis, C., Theodoropoulou, G., Koutsonikas, G., & Papadopoulos, G. (2021). Collision kidney tumour with clear cell renal cell carcinoma and papillary type 1 renal cell carcinoma. A case report and review of the literature. Urologia, 3915603211001673. https://doi.org/10.1177/03915603211001673
Mancebo, S. E., Marchetti, M. A., Hollmann, T. J., Marghoob, A. A., Busam, K. J., & Halpern, A. C. (2015). Melanoma in situ colonizing basal cell carcinoma: a case report and review of the literature. Dermatol Pract Concept, 5(1), 25-30. https://doi.org/10.5826/dpc.0501a04
Mizuta, H., Namikawa, K., Takahashi, A., Ogata, D., Muto, Y., Jinnai, S., . . . Yamazaki, N. (2021). The first case of a collision tumour of melanotrichoblastoma and seborrheic keratosis. Int J Dermatol, 60(2), e54-e56. https://doi.org/10.1111/ijd.15042
Morini, M., Bettini, G., Preziosi, R., & Mandrioli, L. (2004). C-kit gene product (CD117) immunoreactivity in canine and feline paraffin sections. J Histochem Cytochem, 52(5), 705-708. https://doi.org/10.1177/002215540405200515
Pallatto, V. A., & Bechtold, M. A. (2018). Mast cell and plasma cell collision tumour in the spleen of a dog. Vet Clin Pathol, 47(2), 303-306. https://doi.org/10.1111/vcp.12596
Patnaik, A. K., Ehler, W. J., & MacEwen, E. G. (1984). Canine cutaneous mast cell tumour: morphologic grading and survival time in 83 dogs. Vet Pathol, 21(5), 469-474. https://doi.org/10.1177/030098588402100503
Peña, L., De Andrés, P. J., Clemente, M., Cuesta, P., & Pérez-Alenza, M. D. (2013). Prognostic value of histological grading in noninflammatory canine mammary carcinomas in a prospective study with two-year follow-up: relationship with clinical and histological characteristics. Vet Pathol, 50(1), 94-105. https://doi.org/10.1177/0300985812447830
Ribatti, D. (2013). Mast cells and macrophages exert beneficial and detrimental effects on tumour progression and angiogenesis. Immunol Lett, 152(2), 83-88. https://doi.org/10.1016/j.imlet.2013.05.003
Rodríguez, F., Castro, P., & Ramírez, G. A. (2016). Collision Tumour of Squamous Cell Carcinoma and Malignant Melanoma in the Oral Cavity of a Dog. J Comp Pathol, 154(4), 314-318. https://doi.org/10.1016/j.jcpa.2016.03.004
Satter, E. K., Metcalf, J., Lountzis, N., & Elston, D. M. (2009). Tumours composed of malignant epithelial and melanocytic populations: a case series and review of the literature. J Cutan Pathol, 36(2), 211-219. https://doi.org/10.1111/j.1600-0560.2008.01000.x
Scott, J. E., Liptak, J. M., & Powers, B. E. (2017). Malignant collision tumours in two dogs. J Am Vet Med Assoc, 251(8), 941-945. https://doi.org/10.2460/javma.251.8.941
Sfacteria, A., Napoli, E., Rifici, C., Commisso, D., Giambrone, G., Mazzullo, G., & Marino, G. (2021). Immune Cells and Immunoglobulin Expression in the Mammary Gland Tumours of Dog. Animals (Basel), 11(5). https://doi.org/10.3390/ani11051189
Tan, G. C., Chandramaya, S. F., Noordin, A., & S Tay, P. Y. (2021). Collision tumour of the ovary: Fibroma and mature cystic teratoma. Indian J Pathol Microbiol, 64(1), 171-173. https://doi.org/10.4103/IJPM.IJPM_670_19
Yuan, Y., Wang, E. H., & Wang, L. (2021). The first case of a collision tumour of gastrointestinal stromal tumour and intravascular large B cell lymphoma. Ann Hematol. https://doi.org/10.1007/s00277-021-04418-x
Zappulli, V., L.Pena, R.Rasotto, Goldschmidt, M. H., Gama, A., Scruggs, J. L., & Kiupel, M. (2019). Surgical Pathology of Tumours of Domestic Animals. (Vol. Volume 2: Mammary Tumours). Davis-Thompson Foundation.