Lyme disease.


V. I. KONTOS (Β.Ι. ΚΟΝΤΟΣ)
L. V. ATHANASIOU (Λ. Β. ΑΘΑΝΑΣΙΟΥ)
Abstract

Lyme borreliosis is a tickbone, zoonotic, chronic disease with multisystemic clinical signs caused by bacteria of borelia species. It has a worldwide distribution and it is transmitted by the ticks of ixodes species. The reservoir of the causative agent in nature are small rodents, wild mammals and birds. In man, the clinical picture is quite clear: the pathognomonic sign is the chronicum erythema migrans in the acute phase, while in the dog, the clinical picture is not as clear: it looks like that of lupus erythematosus. The most constant symptom is lameness caused by the affection of joints. Diagnosis is based on the detection of antibodies against borrelia by the IFA method. Concerning public health, it is mentioned that in the U.S and in northern European countries, it is the most frequent tickbone disease while in Greece only some sporadic cases have been reported.

Article Details
  • Sezione
  • Review Articles
Downloads
I dati di download non sono ancora disponibili.
Riferimenti bibliografici
Andre-Fontaine G, Clouet-Ruvoen Ν, Ganiere JP. La Borreliose de Lyme. Ree Med Vet 1994,170:669-673.
Bukowski JA. Lyme disease : A tick borne threat to people and pets. Veterinary medicine - Pet practice 1998,346-358.
Greene RT. Canine Lyme Borreliosis. Vet Clin of North Am Small Anim Pract 1991,21:51-64.
Burgdorfer W. Borrelia. J Am Vet Med Assoc 1987,43:479-483.
Wilske B, Preac-Mursic V, Schierz G, Kuhbeck R, Barbur AG, Kramer M. Antigenic Variability of Borrelia burgdorferi. Ann. New York Acad of Sci 1989,539:126-143.
Azuma Y, Isogai E, Isogai H, Kawamura Κ. Canine Lyme disease: clinical and serological evaluations in 21 dogs in Japan. Vet Ree 1994,134:369-372.
Spielman. Tick Information Sheet. Vet Clin of North Am Small Anim Pract 1991,21: 65-73.
Kazmierezak JJ and Sorhage FE. Current understanding of Borrelia burgdorferi infection, with emphasis on its prevention in dogs. J Am Vet Med Assoc 1993,203:1524-1528.
Greene R. Lyme Borreliosis In Clinical Microbiology and Infectious Diseases of the Dog and Cat, 2nd ed, Greene G, WB Saunders, 1990,508-513.
Levy SA, Barthold SW, Dombach DM and Wasmoen TL. Canine Lyme Borreliosis. Small Animal The Compendium, 1993,15(6):833-846.
Madigan JE and Teitler J. Borrelia burgdorferi borreliosis. J Am Vet Med Assoc 1988,192(7):892-896.
Nleisen SW. Lyme Borreliosis. Comparative Pathology Bulletin 1989,12(4):306-307.
Gustafson JM, Burgess EC, Wachal MD and Steinberg H. Intrauterine transmission of Borrelia burgdorferi in dogs. Am J Vet Res 1993,54(6): 882-890.
Stich-Groh V, Chatzipanagiotou S, Raptou V. Antibody Determination Against the Causative Agent of Lyme Disease (Borrelia burgdorferi) in Randomly Collected Sera in Athens, Greece. Δελτίο Ελληνικής Μικροβιολογικής Εταιρείας 1987, 32:234-246.
Magnarelli LA, Anderson JF, Schreirer AB and Ficke CM. Clinical and serologic studies of canine borreliosis. J Am Vet Med Assoc 1987, 191( 9):1089-1094.
May C, Benett D, Carter SD. Lyme disease in the dog. Vet Ree 1990,125:293.
Roush JK, Manley PA, Dueland RT. Rhematoid arthritis subsequent to Borrelia burgdorferi infection in two dogs. J Am Vet Med Assoc 1989,195(7):951-953.
Kornblatt AN, Urband PH, Steere AC. Arthritis caused by Borrelia burgdorferi in dogs. J Am Vet Med Assoc 1985, (186)9:960-964.
Bushmich SL. Lyme Borreliosis in Domestic Animals. Journal of Spirochetal and Tick-Borne Diseases 1994, l(l):24-28.
Appel MJG. Experimental Lyme Disease in Dogs Produces Arthritis and Persistent Infection. The Journal of Infectious Diseases 1993,167: 651-664.
Appel MJG. Lyme Disease in Dogs and Cats. Small Animal The Compendium 1990,12(5): 617-665.
Cohen ND, Carter CN, Thomas MA, Angulo AB, Eugster AK. Clinical and epizootiologic characteristics of dogs seropositive for Borrelia burgdorferi in Texas: 110 cases (1988), J Am Vet Med Assoc 1990,197(7):893-898.
Mandel NS, Senker EG, Bosler EM, Schneider EM. Intrathecal Production of Borrelia burgdorferi- Specific Antibodies in a Dog with Central Nervous System Lyme Borreliosis, Small Animal The Compendium 1993,15(4):581-585.
Henes MG. Myocardial dysfunction associated with Lyme disease. Veterinary Medicine-Pet practice 1989,982-986.
Lindenmayer J, Weber M, Bryant J, Marquez E, Onderdonk A. Comparison of Indirect Immunofluorescent-Antibody Assay, Enzyme-Linked Immunosorbent Assay, and Western Immunoblot for the Diagnosis of Lyme Disease in Dogs. Journal of Clinical Microbiology 1990,92-96.
Moffat CM, Sigal LH, Steere AC, Freeman DA, Dwyer JM. Cellular immune findings in Lyme Disease. Correlation with serum IgM and Disease Activity. The American Journal of Medicine 1984,77:625-632.
Levy SA, Magnarelli LA. Relationship between development of antibodies to Borrelia burgdorferi in dogs and the subsequent development of limb/joint borreliosis. J Am Vet Med Assoc 1992,200(3):344-347.
Magnarelli LA, Anderson JF, Schreirer AB, Ficke CM. Clinical and serologic studies of canine borreliosis. J Am Vet Med Assoc 1987,191(9):1089-1094.
Magnarelli LA, Anderson JF, Schreirer AB, Ficke CM. Persistence of antibodies to Borrelia burgdorferi in dogs of New York and Connecticut. J Am Vet Med Assoc 1990,
(7):1064-1068.
Shin SJ, Chang YF, Jacobson RH, Shaw E, Lauderdale TL, Appel MJ, Lein DH. Cross-reactivity between B.burgdoferi and other spirochetes affects specificity of serotests for detection of antibodies to the Lyme disease agent in dogs. Veterinary Microbiology 1993,36:161-174.
Fisher S.C. The development of a Lyme Disease Vaccine for Use in Canine Practice, Canine Practice-Immunology 1991,3-5.
Stanck G, Pletschette M, Flamm H, Hirsch AM, Aberer E, Kristoferitsch W, Schmutzhard E. European Lyme Borreliosis Annals New York Academy of sciences 1986,274-282.
Santino I, Dastoli F, Sessa R, Del Piano M. Geographical incidence of infection with Borrelia burgdorferi in Europe. Panminerva Med 1997, (39):208-214.
Chatzipanagiotou S, Papandreou-Rakitsis P, Malamou-Ladas H, Antoniou P, Determination of antibody titres for Borrelia burgdorferi in the serum of gipsies living in Attica, Greece, Eur J Clin Microbiol Infect Dis 1991, (11)477-478.
Puoi leggere altri articoli dello stesso autore/i