Assessment of oxidative stress, trace elements, serum biochemistry, and hormones levels in weaned calves with dermatophytosis

PDF (English)
DOI: https://doi.org/10.12681/jhvms.26747
K SEZER
Burdur Mehmet Akif Ersoy University, Faculty of Veterinary Medicine, Department of Internal Medicine, Burdur, Turkey
B HANEDAN
Ataturk University, Faculty of Veterinary Medicine, Department of Internal Medicine, Erzurum, Turkey
M OZCELIK
Fırat University, Vocational School of Health Services, Elazıg, Turkey
A KIRBAS
Bozok University, Faculty of Veterinary Medicine, Department of Internal Medicine, Yozgat, Turkey
Abstract

In this study, it was aimed to evaluate oxidative stress, serum biochemistry, trace elements, minerals, and testosterone and thyroid hormone levels in weaned calves with dermatophytosis. A total of 28 weaned Holstein calves were used in the study, including 6-8 months old, 14 with dermatophytosis (7 males, 7 females) and 14 healthy (7 males, 7 females). The animals were grouped as the diseased and healthy animals, 14 animals in each group as well as the male diseased and the male healthy animals were grouped as 7 animals in each group for the comparison of testosterone levels. The blood analyses were performed using ELISA kits and biochemistry automatic analyzer. There was a significant difference between the diseased and healthy groups for NO (nitric oxide) (P<0.05), TOS (total oxidative stress) (P<0.001), TAC (total antioxidant capacity) (P<0.01). However, in comparison of the diseased and healthy groups, serum biochemistry with the exception of glucose and triglyceride,trace elements except for manganese, minerals, and thyroid hormone levels were not statistically different (P>0.05). In comparison of the diseased and healthy animals for testosterone levels, it was not determined any difference (P>0.05). The present study revealed that dermatophytosis could affect oxidant status in calves with dermatophytosis, and that TOC (total oxidant capacity) and NO as oxidative stress marker might be increased for fungicidal effect in the diseased animals with dermatophytosis.

Article Details
  • Sezione
  • Research Articles
Creative Commons License

Questo lavoro è fornito con la licenza Creative Commons Attribuzione - Non commerciale 4.0 Internazionale.

Authors who publish with this journal agree to the following terms:

· Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution Non-Commercial License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.

· Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g. post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.

· Authors are permitted and encouraged to post their work online (preferably in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.

Downloads
I dati di download non sono ancora disponibili.
Riferimenti bibliografici
Al-Qudah KM, Gharaibeh AA, Al-Shyyab MM (2010) Trace minerals status and antioxidant enzymes activities in calves with dermatophytosis. Biol Trace Elem Res136(1):40-47. doi:10.1007/s12011-009-8525-4.
Aslan O, Aksoy A, Iça T (2010) Serum concentrations of zinc, copper, manganese in young cattle with dermatophytosis. J Fac Vet Med Univ Erciyes 7(1) 29-33.
Atakisi E, Karapehlivan M, Atakişi O, Kontaş T, Maraşlı Ş. (2006) Adenosine deaminase and biochemical liver function tests in the dermatophytic cattle. Bull Vet Inst Pulawy 50, 481-483.
Atakisi O, Oral H, Atakisi E, Merhan O, Pancarci SM, Ozcan A, Marasli S, Polat B, Colak A, Kaya S (2010) Subclinical mastitis causes alterations in nitric oxide, total oxidant and antioxidant capacity in cow milk. Res Vet Sci89(1):10-13.
Beigh SA, Soodan JS, Singh R, Khan AM, Dar MA (2014) Evaluation of trace elements, oxidant/antioxidant status, vitamin C and beta-carotene in dogs with dermatophytosis. Mycoses 57(6):358-365. doi:10.1111/myc.12163
Bendich A (1993) Physiological role of antioxidants in the immune system. J Dairy Sci 76(9):2789-2794.
Brasch J (1997) Hormones, fungi and skin. Mycoses 40:11.
Brasch J, Flader S (1996) Human androgenic steroids affect growth of dermatophytes in vitro. Mycoses 39(9‐10):387-392.
Cambier L, Weatherspoon A, Defaweux V, Bagut ET, Heinen MP, Antoine N, Mignon B (2014) Assessment of the cutaneous immune response during Arthroderma benhamiae and A. vanbreuseghemii infection using an experimental mouse model. Br J Dermatol170(3):625-633. doi:10.1111/bjd.12673
Castillo C, Hernandez J, Lopez-Alonso M, Miranda M, Benedito JL (2003). Values of plasma lipid hydroperoxides and total antioxidant status in healthy dairy cows: preliminary observations. Archives of Animal Breeding 46, 227-233.
Chermette R, Ferreiro L, Guillot J (2008) Dermatophytoses in animals. Mycopathologia 166(5-6):385-405.
Chew BP (1987) Vitamin A and β-carotene on host defense. J Dairy Sci 70(12):2732-2743.
Christian P, West KP Jr (1998) Interactions between zinc and vitamin A: an update. Am J Clin Nutr 68(2 Suppl):435-441. doi:10.1093/ajcn/68.2.435S
Clemons KV, Schär G, Stover EP, Feldman D, Stevens D (1988) Dermatophyte-hormone relationships: characterization of progesterone-binding specificity and growth inhibition in the genera Trichophyton and Microsporum. J Clin Microbiol26(10): 2110-2115.
Deacon JW (1988) Introduction to modern mycology, 2nd ed. Oxford: Blackwell Scientific Publications. 1-239.
Erel O (2004) A novel automated direct measurement method for total antioxidant capacity using a new generation, more stable ABTS radical cation. Clin Biochem37(4):277-285.
Erel O (2005) A new automated colorimetric method for measuring total oxidant status. Clin Biochem38(12):1103-1111.
Erkilic E, Erdogan H, Ogun M, Kirmizigul A, Gokce E, Kuru M, Kukurt A (2016) Relationship between hepcidin and oxidant/antioxidant status in calves with suspected neonatal septicemia. Vet World 9(11):1238-1241.
Gong J, Xiao M (2018) Effect of organic selenium supplementation on selenium status, oxidative stress, and antioxidant status in selenium-adequate dairy cows during the periparturient period. Biol Trace Elem Res. 186(2):430-440. doi: 10.1007/s12011-018-1323-0.
Hashemi SJ, Sarasgani M (2004) A study for determination of relationship between serum testosterone concentration and dermatophytosis due to Epidermophyton floccosum in patients. Iranian J Publ Health 33(1):10-12.
Kahn C, Line S (2010) Dermatophytosis. In: The Merck Veterinary Manual. USA: Merck Co., Inc. Whitehouse Station, N.J.
Karapehlivan M, Uzlu E, Kaya N, Kankavi O, Ural K, Citil, M (2007) Investigation of some biochemical parameters and the antioxidant system in calves with dermatophytosis. Turk J Vet Anim Sci 31(2):85-89.
Kurutas EB, Ozturk P (2016) The evaluation of local oxidative/nitrosative stress in patients with pityriasis versicolor: a preliminary study. Mycoses 59(11):720-725. doi:10.1111/myc.12522.
Larone DH (1995) Medically important fungi: A guide to identification, 4th Edition, American Society for Microbiology, USA. p. 272-4.
Lykkesfeldt J, Svendsen O (2007) Oxidants and antioxidants in disease: oxidative stress in farm animals. Vet J 173(3):502-511.
Malecki EA, Greger JL (1996) Manganese protects against heart mitochondrial lipid peroxidation in rats fed high levels of polyunsaturated fatty acids. J Nutr 126(1):27-33. doi:10.1093/jn/126.1.27.
Martinez-Rossi NM, Peres NT, Rossi A (2017) Pathogenesis of dermatophytosis: Sensing the host tissue. Mycopathologia 182(1-2):215-227. doi:10.1007/s11046-016-0057-9
Miller J, Brzezinska-Slebodzinska E, Madsen F (1993) Oxidative stress, antioxidants, and animal function. J Dairy Sci 76(9):2812-2823.
Miraloglu M, Kurutas EB, Ozturk P, Arican O (2016) Evaluation of local trace element status and 8-Iso-prostaglandin F2 alpha concentrations in patients with tinea pedis. Biol Proced Online 18:1. doi:10.1186/s12575-015-0030-x
Mittal M, Siddiqui MR, Tran K, Reddy SP, Malik AB (2014) Reactive oxygen species in inflammation and tissue injury. Antioxid Redox Signal 20(7):1126-1167. doi:10.1089/ars.2012.5149
Mizokami SS, Hohmann MS, Staurengo-Ferrari L, Carvalho TT, Zarpelon AC, Possebon MI, de Souza AR, Veneziani RC, Arakawa NS, Casagrande R, Verri WA Jr (2016) Pimaradienoic acid inhibits carrageenan-induced inflammatory leukocyte recruitment and edema in mice: Inhibition of oxidative stress, nitric oxide and cytokine production. PLoS One 11(2):e0149656. doi:10.1371/journal.pone.0149656
Nisbet C, Yarim G F, Ciftci G, Arslan HH, Ciftci A (2006) Effects of trichophytosis on serum zinc levels in calves. Biol Trace Elem Res 113(3):273-280. doi:10.1385/bter:113:3:273
Or M, Bakırel, U, Tuncel H, Arun S, Karakoç Y, Dodurka HT, Barutçu UB (2002) Relation of histo-pathological changes with serum zinc and copper levels in dermatologically disease ddogs. J FacVet Med Univ Istanbul 28(2):337-345.
Paksoy N, Ozçelik M, Erkılıç EE, Büyük F, Metin O, Kırmızıgül AH (2013) Serum Copper, Zinc and Manganese Concentrations in Bovine Dermatophytosis in Kars Region. Atatürk Univ J Vet Sci 8(3):210-215.
Pal M, Dave P (2013) Ringworm in cattle and man caused by Microsporium canis: Transmission from dog. Int J Livest Res 3(1):100-103.
Papini R, Nardoni S, Fanelli A, Mancianti F (2009) High Infection Rate of Trichophyton verrucosum in Calves from Central Italy. Zoo noses Public Health, 56 (2):59-64.
Pasa S, Kiral F (2009) Serum zinc and vitamin A concentrations in calves with dermatophytosis. J Fac Vet Med Univ Kafkas15(1):9-12.
Prohaska JR, Brokate B (2001) Lower copper, zinc-superoxide dismutase protein but not mRNA in organs of copper-deficient rats. Arch Biochem Biophys 393(1):170-176. doi:10.1006/abbi.2001.2470.
Quinn PJ, Carter ME, Markey B, Carter GR (1999) Clinical Veterinary Microbiology. p: 381-390. London, England: Mosby-Wolfe.
Radostits OM, Gay CC, Hinchcliff KW, Constable PD (2007) Ringworm. Veterinary Medicine. Saunders Elsevier, Edinburgh, 1476-1478.
Robert R, Pihet M (2008) Conventional methods for the diagnosis of dermatophytes. Mycopathologia 166:295-306.
Roth E (1997) Oxygen free radicals and their clinical implications. Acta Chir Hung 36(1-4): 302-305.
Schaufuss P, Steller U (2003) Haemolytic activities of Trichophyton species. Med Mycol 41(6):511-516.
Schott C, Cai H, Parker L, Bateman K, Caswell J (2014) Hydrogen peroxide production and free radical-mediated cell stress in Mycoplasma bovis pneumonia. J Comp Pathol 150(2-3):127-137.
Shafiei Neek L, Gaeini AA, Choobineh S (2011) Effect of zinc and selenium supplementation on serum testosterone and plasma lactate in cyclist after an exhaustive exercise bout. Biol Trace Elem Res 144(1- 3):454-462. doi:10.1007/s12011-011-9138-2
Szczepanik M, Wilkolek P (2004) Selected parameters of nonspecific immunity in cattle suffering from trychophytosis at different levels of zinc in their serum. Medycyna Weterynaryjna 60(11):1233-1235.
Toyoda H, Himeno S, Imura N (1989) The regulation of glutathione peroxidase gene expression relevant to species difference and the effects of dietary selenium manipulation. Biochim Biophys Acta 1008(3):301-308.
Xavier GA, da Silva LB, da Silva DR, de Moraes Peixoto R, Lino GC, Mota RA (2008) Dermatophytosis caused by Microsporum canis and Microsporum gypseum in free-living Bradypus variegatus (Schiz, 1825) in the state of Pernambuco, Brazil. Braz J Microbiol 39(3):508-510.
Yildirim M, Cinar M, Ocal N, Yagci B, Askar S (2010) Prevalence of clinical dermatophytosis and oxidative stress in cattle. J Anim Vet Adv 9(14):1978-1982.
Zhang J, Wang X, Vikash V, Ye Q, Wu D, Liu Y, Dong W (2016) ROS and ROS-mediated cellular signaling. Oxid Med Cell Longev 2016:4350965.
Puoi leggere altri articoli dello stesso autore/i