Histopathological findings in Dalmatian pelicans (Pelecanus crispus) naturally infected with avian influenza subtype A H5N1 in Bulgaria

PDF (English)
Опубликован: Jan 29, 2018
DOI: https://doi.org/10.12681/jhvms.15493
G. M. STOIMENOV
Department of Infectious Pathology and Food Hygiene, Faculty of Veterinary Medicine
G. V. GOUJGOULOVA
National Diagnostic Research Veterinary Medical Institute
B. NIKOLOV
Department of Clinical Pathology, of Veterinary Medicine, University of Forestry
R. PETROVA
National Diagnostic Research Veterinary Medical Institute
A. TENEVA
Department of Plant Protection, University of Forestry
I. DIMITROVA
Department of Plant Protection, University of Forestry
Аннотация

The aim of this study is to estimate the histopathological changes in visceral organs of naturally infected with the avian influenza virus (AIV) subtype A H5N1 dalmatian pelicans in Bulgaria. The identified gross lesions are: haemorrhagic small intestine, sparse content in gizzard and proventriculus, well defined hyperemia of the tracheal mucosa associated with petechiae, as well as meningeal and brain congestion. The infected birds exhibited the following histopathological changes: edema of the tracheal mucosa with loss of mucosal glands, mild to moderate congestion with focal necrosis and multifocal non suppurative encephalitis and gliosis, mononuclear infiltration in the cecum, and diffuse mononuclear infiltration in the submucosa of the small intestine. The virus was detected by virus isolation (VI) and RT-PCR from tissue samples (lung, trachea, small intestine, brain, proventriculus, cloaca) from the infected birds.

Article Details
  • Раздел
  • Research Articles
Лицензия Creative Commons

Это произведение доступно по лицензии Creative Commons «Attribution-NonCommercial» («Атрибуция — Некоммерческое использование») 4.0 Всемирная.

Authors who publish with this journal agree to the following terms:

· Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution Non-Commercial License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.

· Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g. post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.

· Authors are permitted and encouraged to post their work online (preferably in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.

Скачивания
Данные скачивания пока недоступны.
Библиографические ссылки
Alexander DJ (2007). An overview of the epidemiology of avian influenza. Vaccine. 25:5637-5644.
Austin FJ & Webster RG (1993). – Evidence of ortho- and paramyxoviruses in fauna from Antarctica. J. Wildl. Dis., 29 (4), 568-571.
Becker WB (1966) The isolation and classification of Tern virus: influenza A-Tern South Africa-1961. J Hyg 64: 309–320
Bröjer C, Ågren EO, Uhlhorn H, Bernodt K, Jansson DS, Gavier-Widén D (2012). Characterization of encephalitis in wild birds naturally infected by Highly Pathogenic Avian Influenza (HPAI)-H5N1. Avian Diseases 56(1), 144-152.
Bröjer C, Ågren EO, Uhlhorn H, Bernodt K, Mörner T, Jansson DS, Mattsson R, Zohari S, Thorén P, Berg M, Gavier-Widén D (2009). Pathology of natural highly pathogenic avian influenza H5N1 infection in wild tufted ducks (Aythya fuligula). Journal of Veterinary Diagnostic Investigation, 21, 579-587.
Brown JD, de Stallknecht, Beck JR, et al. (2006). Susceptibility of North American ducks and gulls to H5N1 highly pathogenic avian influenza viruses. Emerg Infect Dis 12:1663–1670.
Comin A, Toft N, Stegeman A, Klinkenberg D, Marangon S (2012). Serological diagnosis of avian influenza in poultry: isthe haemagglutination inhibition test really the ‘gold standard’? Accepted 5 May 2012. Published Online 14 June 2012 2012 Blackwell Publishing Ltd p. 257-264.
Cox, NJ, Fuller F, Kaverin N, Klenk HD, Lamb RA, Mahy BW, McCauley JW, Nakamura K, Palese P and Webster RG (2000). Orthomyxoviridae. In: Virus taxonomy. Seventh report of the international committeeon taxonomy of viruses. Van Regenmortel, M. H. , C. M. Fauquet, D. H. L. Bishop, E. B. Carstens, M. K. Estes, S. M. Lemon, J. Maniloff, M. A. Mayo, D. J. McGeoch, C. R. Pringle, and R.B. Wickner, eds. Academic Press, San Deigo. 585-597.
Ellis TM, Bousfield RB, Bissett LA, Dyrting KC, Luk GS, Tsim ST, Sturm-Ramirez K, Webster RG, Guan Y, Malik Peiris JS (2004). Investigation of outbreaks of highly pathogenic H5N1 avian influenza in waterfowl and wild birds in Hong Kong in late 2002. Avian Pathol 33: 492–505,
Goujgoulova G, Oreshkova N (2007). Surveilance on Avian Influenza in Bulgaria. Avian diseases 51:382–386.
http://www.oie.int/en/animal-health-in-the-world/update-on-avianinfluenza/
/
http://www.oie.int/wahis_2/public/wahid.php/Reviewreport/
Review?page_refer=MapFullEventReport&reportid=17083
Kalthoff D, Breithaupt A, Teifke JP, et al. (2008). Highly pathogenic avian influenza virus (H5N1) in experimentally infected adult mute swans. Emerg Infect Dis 14:1267–1270.
Keawcharoen J, Van Riel D, Van Amerongen G, et al. (2008). Wild ducks as long distance vectors of highly pathogenic avian influenza virus (H5N1). Emerg Infect Dis 14:600–607.
Kwon YK, Joh SJ, Kim MC, et al (2005). Highly pathogenic avian influenza in magpies (Pica pica sericea) in South Korea. J Wildl Dis 41:618–623.
Liu J, Xiao H, Lei F, et al. (2005). Highly pathogenic H5N1 influenza virus infection in migratory birds. Science 309:1206.
Marinova-Petkova A, Georgiev G, Seiler P, Darnell D, Franks J, Krauss S,. Webby RJ, and Webster RG (2012). Spread of Influenza Virus A (H5N1) Clade 2.3.2.1 to Bulgaria in Common Buzzards. Emerging infectious diseases Volume 18, Number 10—October
Molesti E, Wright E, Terregino C, Rahman R, Cattoli G, Temperton NJ (2014). Multiplex Evaluation of Influenza Neutralizing Antibodies with Potential Applicability to In-Field Serological Studies. Journal of Immunology Research.;2014:457932. doi:10.1155/2014/457932.
Morgan IR & Westbury HA (1981). – Virological studies of Adelie penguins (Pygoscelis adeliae) in Antarctica. Avian Dis.,(4), 1019-1026.
OIE Terrestrial Manual, Chapter 2.3.4, 2015
Olsen B, Munster VJ, Wallensten A, Waldenstrom J, Osterhaus ADME., AND Fouchier RAM (2006). Global patterns ofinfluenza A virus in wild birds. Science 312:384–388.
Pálmai N, Erdély K, Bálint A, et al. (2007). Pathobiology of highly pathogenic avian influenza virus (H5N1) infection in mute swans (Cygnus olor). Avian Pathol 36:245–249.
Pasick JP, Berhane Y, Embury-Hyatt C, et al. (2007), Susceptibility of Canada geese (Branta canadensis) to highly pathogenic avian influenza virus (H5N1). Emerg Infect Dis 13:1821–1827.
Schrauwen EJA, Herfst S, Leijten LM, van Run P, Bestebroer TM, Linster M, Bodewes R, Kreijtz J, Rimmelzwaan GF, Osterhaus A, Fouchier RAM, Kuiken T & van Riel D (2012). The Multibasic Cleavage Site in H5N1 Virus Is Critical for Systemic Spread along the Olfactory and Hematogenous Routes in Ferrets. Journal of Virology 86(7), 3975-3984.
Shinya K, Makino A, Hatta M, Watanabe S, Kim JH, Hatta Y, Gao P, Ozawa M, Le QM & Kawaoka Y (2011). Subclinical Brain Injury Caused by H5N1 Influenza Virus Infection. Journal of Virology 85(10), 5202-5207.
Shortridge KF, Gao P, Guan Y, Ito T, Kawaoka Y, Markwell D, Takada A, Webster RG (2000). A review of interspecies transmission of influenza viruses: the Hong Kong perspective. In Proceedings of the European Society for Veterinary Virology Symposium on influenza viruses of wild and domestic animals, 16-18 May 1999, Ghent. Veterinary Microbiology 74: 141-147.
Sonnberg S, Webby RJ, Webster RG (2013). Natural history of highly pathogenic avian influenza H5N1. Virus Res 2013; 178:63-77.
Spackman E, Senne DA, Myers TJ, Bulaga LL, Garber LP, Perdue ML, Lohman K., Daum LT & Suarez DL (2002). Development of a realtime reverse transcriptase PCR assay for type A influenza virus and the avian H5 and H7 hemagglutinin subtypes. J. Clin. Microbiol., 40, 3256–3260.
Suarez DL, Perdue ML (1998). Multiple alignment of the non-structural genes of influenza A viruses. Virus Research 54: 59-69.
Swayne DE (2007). Understanding the complex pathobiology of high pathogenicity avian influenza viruses in birds. Avian Diseases 51, 242-249.
Tang X, Tain G, Zhao J, Zhou KY (1998). Isolation and characterization of prevalent strains of avian influenza viruses in China [article in Chinese]. Chinese Journal of Animal and Poultry Infectious Diseases 20: 1-5.
Teifke JP, Klopfleisch R, Globig A, et al.: (2007). Pathology of natural infections by H5N1 highly pathogenic avian influenza virus in mute (Cygnus olor) and whooper (Cygnus cygnus) swans. Vet Pathol 44:137–143.
Tong S, Li P, Rivailler C, Conrardy C, Alvarez-Castille D, Chen L, Recuenco S, Ellison JA, Davis CT, York IA, Turmelle AS, Moran D, Rogers S, Shi M, Tao Y, Weil MR, Tang K, Rowe LA, Sammons S, Xiyan X, Frace M, Lindblade KA, Cox NJ, Anderson LJ, Rupprect CE, and Donis RO (2012). A distinct lineage of influenza A virus from bats. 2012. PNAS, 109 (11): 4269-4274
Наиболее читаемые статьи этого автора (авторов)