Effects of whey-enriched drinking water on fattening merino lamb growth, hemogram, inflammation, oxidant and antioxidant parameters


Опубликован: Jan 18, 2024
Обновлен: 2024-01-18
E Danyer
https://orcid.org/0000-0002-7922-7384
T Bilal
A Altiner
H Eseceli
Аннотация

This study aimed to evaluate the oxidative stress and inflammation status of ad libitum whey consumption as drinking water on fatting Merino lambs (n=24). Lambs were randomly divided into two groups and received ad libitum freshwater or whey enriched water and had clover as roughage and lamb grower feed as concentrate daily. Blood samples were collected before the trial (T1), on the 15th (T2) and 30th (T3) days and analyses were conducted on hemogram, serum antioxidant enzymes (Superoxide dismutase, SOD; Glutathione peroxidase, GSH-Px) inflammation response (C-Reactive Protein, CRP), complement activation, and chemokine marker (complement component 4, C4), lymphocyte activation factor (Interleukin 1 beta, IL-1 β), systemic inflammation cytokine (Tumor necrosis factor-alpha, TNF-α), lipid peroxidation marker (Malondialdehyde, MDA). The rate of hematocrit was found to be higher in the experimental group in T3 (35.55 ± 10.54) compared to the control group (44.50 ± 2.58). The platelet amounts were found to be higher in the whey group in T2 and T3 compared to the control group (p<0.05). In conclusion, with the use of whey protein-enriched drinking water, no significant change was observed in the amounts of TNF-α, SOD, MDA, IL-1β, C4, CRP under these study conditions.

Article Details
  • Раздел
  • Research Articles
Скачивания
Данные скачивания пока недоступны.
Библиографические ссылки
ory diagnosis in veterinaray practice. İstanbul University Press, İstanbul (In Turkish).
Byers SR, Kramer JW (2011) Normal hematology of sheep and goats. In:
DJ Weiss, KJ Wardrop (Eds. ), Schalm’s veterinary hematology. 6th
ed, John Wiley Sons, New York: pp 836-842.
Danyer E, Bilal T, Altiner A, Aytekin İ, Atalay H (2021) The effect of
vitamin E treatment on selected immune and oxidative parameters in
Kivircik ewes suffering from transport stress. Journal of Animal Phy
(S1): 34-41.
Dayani O, Tahmasbi R, Khezri A, Sabetpay AR (2011) Effect of feeding
dietary treated wheat straw with urea and whey on fattening lambs
performance. Iranian Journal of Applied Animal Science 1 (4): 265-
DePeters EJ, Fisher LJ, Stone JL (1986) Effect of adding dried whey to
starter diet of early and late weaned calves. Journal of Dairy Science
(1): 181-186.
Dinarello CA (1996) Biologic basis for interleukin-l in disease. The Journal of the American Society of Hematology 87 (6): 2095-2147.
El-Agamy EI (2007) The challenge of cow milk protein allergy. Small
Ruminant Research 68 (1-2): 64-72.
Eseceli H, Esen S, Keten M, Altıner A, Bilal T (2021) Effect of whey
protein-enriched water on performance and in vivo carcass measurements in fattening merino lambs. Alinteri Journal of Agricultural Sciences 36 (1): 61-65.
Fallah R (2019) Effects of adding whey and molasses on corn silage quality, growth performance and health of Simmental fattening calves.
Journal of Livestock Science 10 (2):91-96.
Gabay C, Kushner I (1999) Acute-phase proteins and other systemic responses to infllammation. The New England Journal of Medicine 340
(6): 448-454.
Galloway DL, Goetsch AL, Forster LA, Brake AC, Johnson Z B (1993)
Digestion, feed intake, and live weight gain by cattle consuming bermudagrass and supplemented with different grains. Journal of Animal
Science71 (5): 1288-1297.
Gandhi K, Devi S, Gautam PB, Sharma R, Mann B, Ranvir S, Sao K, Pandey V (2019) Enhanced bioavailability of iron from spray dried whey
protein concentrate-iron (WPC-Fe)complex in anaemic and weaning
conditions. Journal of Functional Foods 58 (March): 275-281.
Giráldez FJ, Santos N, Santos A, Valdés C, López S, Andrés S (2021) Fattening lambs with divergent residual feed intakes and weight gains:
unravelling mechanisms driving feed efficiency. Animal Feed Science and Technology 273 (2021):114821.
Hassan T, Abdel-Fattah F, Farid A, Kamel E. (2016) Effect of feeding guava waste on growth performance, diet digestibility, carcass characteristics and production profitability of ossimi lambs. Egyptian Journal
of Nutrition and Feeds 19 (3): 461-472.
Håversen L, Ohlsson BG, Hahn-Zoric M, Hanson LÅ, Mattsby-Baltzer
I (2002) Lactoferrin down-regulates the LPS-induced cytokine production in monocytic cells via NF-κB. Cellular Immunology 220 (2):
-95.
Hoffman JR, Falvo MJ (2004) Protein - which is best? Journal of Sports
Science and Medicine3 (3): 118-130.
Hulmi JJ, Lockwood CM, Stout JR (2010) Effect of protein/essential amino acids and resistance training on skeletal muscle hypertrophy: A
case for whey protein. Nutrition and Metabolism 7: 28-31.
Kushibiki S, Hodate K, Kurisaki J, Shingu H, Ueda Y, Watanabe A, Shinoda M (2001) Effect of β-lactoglobulin on plasma retinol and triglyceride concentrations, and fatty acid composition in calves. Journal of
Dairy Research 68 (4): 579-586.
Margaritelis NV, Chatzinikolaou PN, Bousiou FV, Malliou VJ, Papadopoulou SK, Potsaki P, Theodorou AA, Kyparos A, Geladas ND, Nikolaidis MG, Paschalis V (2020) dietary cysteine intake is associated
with blood glutathione levels and isometric strength. International
Journal of Sports Medicine 42 (05): 441-447.
Marnett LJ (1999) Lipid peroxidation - DNA damage by malondialdehyde. Mutation Research 424: 83-95.
Mattsby-Baltzer I, Roseanu A, Motas C, Elverfors J, Engberg I, Hanson,
L A Å (1996) Lactoferrin or a fragment thereof inhibits the endotoxin-induced interleukin-6 response in human monocytic cells. Pediatr
Res 40 (2): 257-262.
Mcgreal EP, Hearne K, Spiller OB (2012) Immunobiology off to a slow
start : under-development of the complement system in term newborns is more substantial following premature birth. Immunobiology
(2): 176-186.
Nkosi BD, Meeske R (2010) Effects of whey and molasses as silage additives on potato hash silage quality and growth performance of lambs.
South African Journal of Animal Sciences 40 (3): 229-237.
Pal S, Radavelli-Bagatini S (2013) The effects of whey protein on cardiometabolic risk factors. Obesity Reviews 14 (4): 324-343.
Prasad K (2006) C-Reactive Protein ( CRP )lowering agents. Cardiovascular Drug Reviews 24 (1): 33-50.
Rapetti L, Falaschi U, Lodi R, Vezzoli F, Tamburin, A, Greppi GF, Enne G
(1995) The effect of liquid whey fed to dairy goats on milk yield and
quality. Small Ruminant Research 16 (3): 215-220.
Ribadeau-Dumas B, Grappin R (1989) Milk protein analysis. Le Lait 69
(5): 357-416.
Rokka S, Korhonen H, Nousiainen J, Marnila P (2001) Colostral whey
concentrate supplement increases complement activity in the sera of
neonatal calves. Journal of Dairy Research 68 (3): 357-367.
Ronghui S (2016) The reasearch on the anti-fatigue effect of whey protein powder in basketball training. The Open Biomedical Engineering
Journal 9 (1): 330-334.
Rutherfurd KJ, Gill HS (2000) Peptides affecting coagulation. British
Journal of Nutrition, 84 (Suppl. 1): S99-S102.
Schingoethe DJ (1976) Whey utilization in animal feeding: a summary
and evaluation. Journal of Dairy Science, 59 (3) 556-570.
Susmel P, Spanghero M, Mills CR, Stefanon B (1995) Rumen fermentation characteristics and digestibility of cattle diets containing different whey:maize ratios. Animal Feed Science and Technology, 53
(1): 81-89.
Thivend P (1978) Use of whey in feeding ruminants. World Animal Review (12):20-24.
Tokajuk A, Zakrzeska A, Chabielska E, Car H (2019) Whey protein concentrate limits venous thrombosis in rats. Applied Physiology, Nutrition and Metabolism 44 (8): 907-910.
Wang H, Zhong X, Shi W, Guo B (2011) Study of malondialdehyde
(MDA) content , superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) activities in chickens infected with avian infectious
bronchitis virus. African Journal of Biotechnology 10 (45): 9213-
Wang J, Radics G, Whelehan M, O’Driscoll A, Healy AM, Gilmer JF,
Ledwidge M (2018) Novel iron-whey protein microspheres protect
gut epithelial cells from iron-related oxidative stress and damage and
improve iron absorption in fasting adults. Acta Haematologica 138
(4): 223-232.
Xu R, Liu N, Xu X, Kong B (2011) Antioxidative effects of whey protein
on peroxide-induced cytotoxicity. Journal of Dairy Science 94 (8):
-3746.
Zhao Y, Weaver AC, Fellner V, Payne RL, Kim SW (2014) Amino acid
fortified diets for weanling pigs replacing fish meal and whey protein
concentrate: Effects on growth, immune status, and gut health. Journal of Animal Science and Biotechnology 2014 (57): 1-10.
ZoBell DR, Okine EK, Olson KC, Wiedmeier RD, Goonewardene LA,
Stonecipher C (2005) Effects of feeding wheat straw and middlings
ensiled with whey on digestibility and growth of cattle. Canadian
Journal of Animal Science 85 (1): 69-74.