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Association between haematopoietic stem cell transplantation and distress - anxiety - depression

Published: Φεβ 7, 2019
Stress distress anxiety depression haematopoietic stem cell transplantation bone marrow transplantation άγχος Ιανουάριος-Μάρτιος 2016 κατάθλιψη μεταμόσχευση αιμοποιητικών κυττάρων μεταμόσχευση μυελού των οστών Στρες ψυχική δυσφορία
Asimina Kiropoulou
Maria Polikandrioti
Introduction: In recent decades, more and more studies indicate that haematopoietic stem cell transplantation triggers numerous mental disorders to the haematological patient. Aim: The aim of the present study was to review the literature on the occurrence of mental disorders, such as distress, anxiety and depression in hematological patients undergoing haematopoietic stem cell transplantation. Material-Method: The method of this study included research of the literature from reviews and researches in «pubmed» and «google scholar» databases, which referred to the association between haematopoietic stem cell transplantation and the occurrence of psychiatric disorders. The search covered the period 2000-2015. Results: According to the literature, the process of bone marrow transplantation is often associated with the onset of distress, anxiety and depression in patients, which may adversely affect their compliance to treatment, the outcome of the procedure, and survival rates. However, many patients are reluctant to express their feelings, and are not questioned by health professionals about their mental worries. As a result, the psychological aspects of their disease may be underestimated. Furthermore, in this group of patients that display numerous physical symptoms, is difficult to diagnose and treat psychological aspects because they often mimic those of their disease. Conclusions: The systematic appraisal of distress, anxiety and depression should be an integral part of the treatment of hematological patients undergoing transplantation.
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Εθνικός Οργανισμός Μεταμοσχεύσεων. Μεταμόσχευση αιμοποιητικών κυττάρων και μυελού των οστών. Διαδικτυακή σελίδα: Ημερομηνία πρόσβασης: 5-5-2014.
Slovacek L, Slovackova B. Quality of life in oncological and hematooncological patients after hematopoietic stem cell transplantation: The effect of selected psychosocial and health aspects on quality of life: A review of the literature. Rep Pract Oncol Radiother 2007; 12(1): 53-59.
Mahendra Pr, Revell P, Kenyon M. Autologous stem cell transplant. Lymphoma Association 2013; 1-84. Διαδικτυακή σελίδα: htpp:// Ημερομηνία πρόσβασης: 20-4-2014.
Roberts K, Wareham D, Ellis M, Bloor A, Revell P, Ardeshna K. Allogeneic stem cell transplants. Lymphoma Association 2008; Διαδικτυακή σελίδα: htpp:// Ημερομηνία πρόσβασης: 20-4-2014.
Μουσσάς ΓΙ, Καρκανιάς ΑΠ, Παπαδοπούλου Α. Ψυχολογικά και ψυχιατρικά προβλήματα στους ασθενείς Γενικού Νοσοκομείου με καρκίνο 2008; Ψυχιατρική 19(2): 124-144.
Albrecht T, Rosenzweig M. Management of Cancer Related Distress in Patients with a Hematological Malignancy. J Hosp Palliat Nurs 2012; 14(7): 462-468.
Siegel SD. Psychosocial considerations in hematopoietic stem cell transplantation: implications for patient quality of life and post-transplant survival. Community Oncology 2008; 5: 407-411.
Khan AG, Irfan M, Shamsi TS, Hussain M. Psychiatric Disorders in Bone Marrow Transplant. JCPSP 2007; 17(2): 98-100.
Fife BL, Huster GA, Cornetta KG, Kennedy VN, Akard LP, Broun ER. Longitudinal Study of Adaptation to the Stress of Bone Marrow Transplantation. Journal of Clinical Oncology 2000; (18): 1539-1549.
Breitbart WS, Alici Y. Προοπτικές: Ψυχο-Ογκολογία. Harvard Rev Psychiatry 2009; 17(6): 361-376.
Lee SJ, Loberiza FR, Antin JH, Kirkpatrick T, Prokop L, Alyea EP et al. Routine screening for psychosocial distress following hematopoietic stem cell transplantation. Bone Marrow Transplantation 2005; (35): 77-83.
Trask PC, Paterson A, Riba M, Brines B, Griffith K, Parker P et al. Psychosocial considerations: Assessment of psychosocial distress in prospective bone marrow transplant patients. Bone Marrow Transplantation 2002; (29): 917-925.
Holland JC, Alici Y. Management of Distress in Cancer Patients. The Journal of Supportive Oncology 2010; (8): 4-12.
Lee SJ, Katona LJ, De Bono SE, Lewis KL. Routine screening for psychological distress on an Australian inpatient haematology and oncology ward: impact on use of psychosocial services. MJA 2010; (193): S74-S78.
Cooke L, Gemmill R, Kravits K, Grant M. Psychological Consequences of Hematopoieitc Stem Cell Transplant. Semin Oncol Nurs 2009 May; 25(2): 139-150.
Ηγουμένου Α. Σχέση κατάθλιψης και καρκίνου. Ψυχιατρική 2010; 21(3): 205-216.
Treleaven J, Barrett J. Introduction to bone marrow transplantation. Bone Marrow Transplantation in Practice 1992; (1): 3-5.
Mosher CE, Redd WH, Rini CM, Burkhalter JE, DuHamel ΚΝ. Physical, psychological, and social sequelae following hematopoietic stem cell transplantation: a review of the literature. Psychoooncology 2009; 18(2): 113-117.
Duckworth KE, Forti AM, Russell GB, Naik S, Hurd DD, McQuellon RP. Hematopoietic Stem Cell Transplant Candidate Prior to Hematopoietic Stem Cell Transplantation. Am J Hosp Palliat Care. 2014; 31(8): 853-854.
Larsen J, Nordström G, Ljungman P, Gardulf A. Symptom Occurrence, Symptom Intensity, and Symptom Distress in Patients Undergoing High‐dose Chemotherapy With Stem‐cell Transplantation. Cancer Nursing 2004; 27(1): 55-64.
Rischer J, Scherwath A, Zander AR, Koch U, Schulz-Kindermann F. Sleep disturbances and emotional distress in the acute course of hematopoietic stem cell transplantation. Bone Marrow Transplantation 2009; (44): 121-128.
Jim HSL, Syrjala KL, Rizzo D. Supportive Care of Hematopoietic Cell Transplant Patients. ASMBT Biol Blood Marrow Transplant 2012; (18): S12-S16.
Levy MR, Fann JR. The Neuropsychiatry of Hematopoietic Stem Cell Transplantation. Eur. J. Psychoatr. 2006; 20(2): 107-128.
Wittmann M, Vollmer T, Schweiger C, Hiddemann W. The relation between the experience of time and psychological distress in patients with hematological malignancies. Palliative and Supportive Care 2006; (4): 357-363.
Artherholt SB, Hong F, Berry DL, Fann JR. Risk Factors for Depression in Patients Undergoing Hematopoietic Cell Transplantation. Biol Blood Marrow Transplant. 2014; 20(7): 946-950.
Syrjala KL, Langer SL, Abrams JR, Storer B, Sanders JE, Flowers ME et al. Recovery and Long-term Function After Hematopoietic Cell Transplantation for Leukemia or Lymphoma. JAMA 2004; 291(19):2335-2343.
Meyer F, Ehrlich M, Petect J. Psycho – Oncology: A Review for the General Psychiatrist. Focus 2009; 7(3): 317-331.
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