The effect of reduced dose of PGF2α on certain reproductive parameters in awassi yearlings in anestrus synchronisation protocol following the end of the of the breeding season


Published: Jan 20, 2023
Keywords:
sheep sponge reduced dose Pgf2α anoestrous season synchronisation
I Ozbilek
https://orcid.org/0000-0001-8658-5916
Y Ergun
A Gözer
O Bahan
S Alasahan
Abstract
The aim of this study was to investigate the effect of the administration of half or full dose of prostaglandin
F2α (PGF2α; Gestavet Prost, d-cloprostenol, HIPRA®) injection in a routine synchronization protocol following the
end of the breeding period including intravaginal sponge (medroxyprogesterone acetate; Espanjovet, HIPRA®) and
eCG (Oviser 500, HIPRA®) on certain fertility parameters in ewes.Two hundred thirty-eight Awassi yearlings (aged
one year old) divided into two groups:116 ewes received a half dose (HSDP; 37.5 μg) of PGF2α and 122 ewes received
full dose (FSDP;75 μg).The pregnancy rates were 67.2% and 72.1% for HSDP and FSDP, respectively (P>0.05).
The lambing rates were 64.7% and 63.9% for HSDP and FSDP, respectively (P>0.05).The single lambing rate in
HSDP(94.7%) was higher (P<0.05) compared to that in FSDP (73.1%). The twin and multiple birth rates of FSDP
was higher (P<0.05) than HSDP. As a result, it was inferred that aHSDP could be used in Awassi yearlings without
experience of lamb care and in a herd in which single lambing was preferable. Moreover, due to the fact that it is more
affordable and not detrimentalto fertility, it was concluded that HSDPcan offer an advantage in large flocks and can be
used for manipulating fecundity ratesin yearlings.
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References
Abecia JA, Forcada F, González-Bulnes A (2012) Hormonal control of reproduction in small ruminants. Animal Reproduction Science. 130 (3–4): 173-179.
Akçapinar H (1994) Sheep Production. Firsth ed, Medisan Press, Ankara: pp 51-176.
Alaçam E (2005) Control of Breeding. In: Obstetrics and Infertility of Domestic Animals. 5th edition, Medisan Press, Ankara: pp 23–74
Alaçam E (2007) Control of Breeding. In: Obstetrics and Infertility of Domestic Animals. 6th edition, Medisan Press, Ankara: pp 71–80.
Alaçam E (2010) Examination of Female Genital Organ. In: Obstetrics and Infertility of Domestic Animals. 3rd edition, Medisan Press, Ankara: pp 55-68
Altınçekiç SO, Koyuncu M (2017) Comparison of effects of CIDR and prostaglandin applications on the reproductive performance of Kivircik ewes in anestrous. Journal of Tekirdag Agricultural Faculty. 14(1): 9-15.
Altinçekiç SO, Koyuncu M, Duru S (2018) Effect on fertility of PMSG applications in different doses in addition to flushing in Kivircik ewes. Mediterranean Agricultural Sciences. 31(1): 87-91.
Ataman MB, Aköz M, Akman O (2006) Induction of synchronized oestrus in Akkaraman cross-bred ewes during breeding and anoestrus seasons: The use of short-term and long-term progesterone treatments. Revue de MédecineVétérinaire. 157(5): 257–260.
Ataman MB, Aköz M, Fındık M, Saban E (2009) Induction of synchronized oestrus in Akkaramancross-bred ewes treated with prostaglandin F2 alpha, norgestomet and sponges impregnated with different doses of fluorogestene acetate at the beginning transitional period. The Journal of the Faculty of Veterinary Medicine University of Kafkas. 15(5): 801–805.
Bülbül B, Kırbas M, Aktas AH, Köse M (2014) Investigation of accelerated lambing possibility of Anatolian merino sheep. Journal of the Faculty of Veterinary Medicine University of Kafkas. 20(1): 19-26.
Cerón JH, Méndez JV, Quintero LZ (2001) Regresión del cuerpolúteo y presentacióndelestroenovejas con dos inyecciones de prostaglandina con 8 días de intervalo. Técnica Pecuariaen México. 39(1): 53–57.
Chohan KR (1998) Estrus synchronization with lower dose of Pgf2α and subsequent fertility in subestrous buffalo.
Theriogenology. 50(7): 1101–1108.
Daşkın A (2001) Effect of PMSG injections on fertility in the synchronized Akkaraman ewes. Ankara Üniv. Vet. Fak. Derg. 48(02):165-167.
Da Silva AWMV, Anderson GW, Gwazdauskas FC, McGilliard ML, Lineweaver JA (1981) Interrelationships with oestrousbehavior and conception in dairy cattle. Journal of Dairy Science. 64(12): 2409–2418.
Doğruer G, Ergün Y, Karaca F, Sarıbay MK, Ateș CT, Aköz M, Aydın I (2015) The effect of applications of eCG and PGF2α at different times with FGA containing vaginal sponges on reproductive parameters in ewes at anoestrous season. Eurasian Journal of Veterinary Sciences. 31(3): 158–162.
Emrelli AZ, Kaya HH, Tek C (2003) Effect of melatonin and progesterone treatment on induction of oestrus and fertility in out-of-season in merino ewes. Journal of The Faculty of Veterinary Medicine Istanbul University. 29(2): 267–275.
Esen F, Bozkurt T (2001) Effect of flushing and oestrus synchronization application on fertility in Akkaraman sheep. Turkish Journal of Veterinary and Animal Sciences. 25(3): 365-368.
Granados-Villarreal LM, Zarco L, Mejía O, Sánchez-Torres MT, Pablos-Hach JL (2017) Luteolytic efficiency of reduced doses of cloprostenol in the ewe. Effect of progesterone concentrations at the time of treatment. Animal Reproduction Science. 186: 68-76.
Herrera HL, Feldman SD, Zarco QL, Valencia MJ, Ortiz HA, Ángeles CS (1990) Evaluación del efecto luteolítico de la prostaglandina F2 alfa en diferentes días del ciclo estral de la borrega. Veterinaria México. 21(2): 143–147.
Hafez ESE, Hafez B (1993) Sheep and Goat. In: Reproduction in farmanimals. Sixth ed, Lea&Febiger, Philadelphia: pp 172-191
Juengel JL, Haworth JD, Rollyson MK, Silva PJ, Sawyer HR, Niswender GD (2000) Effect of dose of prostaglandin F2α on steroidogenic components and oligonucleosomes in ovine luteal tissue. Biology of Reproduction. 62(4): 1047–1051.
Karaca F, Ataman MB, Coyan K (2009) Synchronization of oestrus with short-and long-term progestogen treatments and the use of GnRH prior to short-term progestogen treatment in ewes. Small Ruminant Research. 81(2–3): 185–188.
Kaymakçı M, Özder M, Karaca O, Torun O, Baş Z, Koşum N (2009) Turkey Breeding sheep strategy. Uludağ Üniversitesi Ziraat Fakültesi Dergisi. 23(2): 67-77
Kılboz EI, Karaca F (2010) Induction of estrus with flugeston acetate–vaginal sponge and norgestomet ear implant treatments in young goats in non-breeding season. Van Veterinary Journal. 21(1):1–6.
Koyuncu M, Uzun ŞK, Şengül L (2001) Synchronization of Oestrus and the Possibilities of Improving Reproductive Performance by using Progestagen and Different Doses of PMSG in Kıvırcık Ewes. Turkish Journal of Veterinary and AnimalSciences. 25(6): 971-974.
Köse M, Kırbas M, Bülbül B, Dursun S (2012) The effect of GnRH or hCG injection at the beginning of short-term intravaginal sponge application on reproductive performance in HASAK and HASMER ewe types in the breeding season. Uludağ University Journal of the Faculty of Veterinary Medicine. 31(2): 21-27.
Köse M, Kırbas M, Bülbül B, Dursun S, Demirci U (2016) Investigation of possibility of increasing lamb production with flushing plus ram effect or the administration of various pregnant mare serum gonadotropin doses in Akkaraman ewes. Ataturk University Journal of Veterinary Sciences. 11(1): 54–59.
Ono H, Fukui Y, Terawaki Y, Ohboshi K, Yamazaki D (1982) An intravulvosubmucous injection of prostaglandin F2α in anoestrous cows. Animal Reproduction Science. 5(1): 1–5.
Özbey O, Tatli P (2002) The effect of oestrus synchronization and flushing on reproduction of Awassi ewes. Anim. Breed Abst. 70(6): 3552.
Ozis S, Kaymakcı M (2003) Sexual behaviours in bucks. Journal of Animal Production. 44(1): 69-75.
Ozyurtlu N, Bademkıran S (2010) Estrus Synchronization and Induction of Estrus Methods in Sheep. Journal of VeterinaryFaculty of Dicle University. 1: 17-22.
Ozyurtlu N, Yesilmen S, Kücükaslan I (2008) The effectiveness of using antibiotic with intravaginal sponge and duration of sponge treatments on the vaginal flora and fertility in anoestrous ewes. Journal of Animal and Veterinary Advances. 7(6): 723–727.
Ribeiro ES, Bisinotto RS, Favoreto MG, Martins LT, Cerri RLA, Silvestre FT, Santos JEP (2012) Fertility in dairy cows following presynchronization and administering twice the luteolytic dose of prostaglandin F2α as one or two injections in the 5-day timed artificial insemination protocol. Theriogenology. 78(2): 273–284.
Tajaddodchelik A, Torun O, Ergün Y (2020) The effects of controlled internal drug release for different days on the reproductive performance of out of mating season sheep. Journal of Agriculture, Food, Environment andAnimalSciences. 1(1): 28-38.
Uçar M, Ozyurtlu N (2015) Control of Breeding In Sheep and Goats, In: Obstetrics and Gynecology in Domestic Animals. Malatya: Medipres Publish. pp 491–505.
Wildeus S (2000) Current concepts in synchronization of oestrus: Sheep and goats 1, 2. Journal of Animal Science. 77:1–14.
Wiltbank MC, Baez GM, Cochrane F, Barletta RV, Trayford CR, Joseph RT (2015) Effect of a second treatment with prostaglandin F2α during the Ovsynch protocol on luteolysis and pregnancy in dairy cows. Journal of Dairy Science. 98(12): 8644–8654.
Wiltbank MC, Souza AH, Carvalho PD, Bender RW, Nascimento AB (2011) Improving fertility to timed artificial insemination by manipulation of circulating progesterone concentrations in lactating dairy cattle. Reproduction, Fertility and Development. 24(1): 238–243.
Yadi J, Moghaddam MF, Khalajzadeh S, Solati AA (2011) Comparison of estrus synchronization by PGF2α, CIDR and sponge with PMSG in Kalkuhiewes on early anestrous season. In: International Conference on Asia Agriculture and Animal, IPCBEE (Vol. 13, pp. 61-65).
Yılmaz M, Bardakçıoğlu HE, Tașkın T (2009) Use of the ram effect and its importance in sheep breeding. Hayvansal Üretim (Journal of Animal Production). 50(2): 52-59.
Zarkawi M, Al-Merestani MR, Wardeh MF (1999) Induction of synchronized oestrous and early pregnancy diagnosis in Syrian Awassi ewes, outside the breeding season. Small Ruminant Research. 33(1): 99–102.
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