The contribution of laboratory animals to diagnostic imaging research in Greece

PDF (English)
Veröffentlicht: Ιαν 29, 2018
DOI: https://doi.org/10.12681/jhvms.15547
S. TSELEPIDIS
Μilitary Veterinary Hospital and Training Center KENOK
K. VASSIOU
Department of Anatomy, Faculty of Medicine, University of Thessaly
D. ARVANITIS
Department of Anatomy, Faculty of Medicine, University of Thessaly
C. KALOGEROPOULOU
Department of Radiology, Department of Medicine, University of Patras
K. MARINOU
Ministry of Rural Development and Food, Department of Animal Welfare
Abstract

Biomedical research in Greece has rapidly developed during the last 30 years. Diagnostic imaging groundwork is a significant field of interest which has been developed by taking advantage of the basic and applied research capacities including the use of small and large animal models, conventional and/or genetically modified ones. This important outbreak in research has been enhanced by the construction of modern facilities in universities, medical and other academic research centers, the use of new advanced installed equipment, modern imaging techniques, specific contrast media and, of course, specialized personnel. In this manuscript, the research performed regarding diagnostic imaging techniques using animal models in Greece since 1983 is presented. More specifically a recording of the Greek research centers, the number of researchers, species and figures of animal models, diagnostic imaging techniques used, as well as the contribution of projects in the evolution of diagnostic imaging in medicine and veterinary science is presented.

Article Details
  • Rubrik
  • Review Articles
Creative-Commons-Lizenz
Dieses Werk steht unter der Lizenz Creative Commons Namensnennung - Nicht-kommerziell 4.0 International.

Authors who publish with this journal agree to the following terms:

· Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution Non-Commercial License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.

· Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g. post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.

· Authors are permitted and encouraged to post their work online (preferably in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.

Downloads
Keine Nutzungsdaten vorhanden.
Literaturhinweise
Bateson P (1986) When to experiment on animals. New Scientist 109:30-32
Balta SC (2006) The history of hellenic radiology. Doctoral thesis. University of Thessaly Medical School Laboratory of radiology, pp.166-167.
Bourantas CV, Kourtis IC, Plissiti ME, Fotiadis DI, Katsouras CS, Papafaklis MI, Michalis LK (2005) A method for 3D reconstruction of coronary arteries using biplane angiography and intravascular ultrasound images. Comput Med Imaging Graph 29(8):597-606.
Brønstad A, Dontas I (2011) Imaging techniques. In: (eds.: CRC Press, Taylor & Francis Group) The COST Manual of Laboratory Animal Science and Care, pp. 287-311.
Constantinidis J,Bohr C,Greess H,Aigner T,Zenk J, Prokopakis E, Iro H (2005) Fat obliteration in paranasal sinuses: a comparative magnetic resonance imaging and histopathologic study. Laryngoscope 115(4):717-23.
Detorakis ET, Drakonaki EE, Ginis H, Karyotakis N, Pallikaris IG (2014) Evaluation of iridociliary and lenticular elasticity using shear-wave elastography in rabbit eyes. Acta Medica (Hradec Kralove) 57(1):9-14.
Dimakakos PB, Stefanopoulos T, Doufas AG, Papasava M, Gouliamos A, Mourikis D, Deligiorgi H (1998) The cerebral effects of carbon dioxide during digital subtraction angiography in the aortic arch and its branches in rabbits. AJNR Am J Neuroradiol 19(2):261-6.
Dimakakos Ε (2006) Interstitial magnetic resonance lymphography: an experimenatl and a clinical trial. Doctoral thesis. Kapodistrian University of Athens Medical School Laboratory of radiology, pp. 16-88.
Fountos G, Yasumura S, Glaros D (1997) The skeletal calcium/phosphorus ratio: a new in vivo method of determination. Med Phys 24(8):1303-10.
Garofalakis A, Zacharakis G, Meyer H, Economou EN, Mamalaki C, Papamatheakis J, Kioussis D, Ntziachristos V, Ripoll J (2007) Threedimensional in vivo imaging of green fluorescent protein-expressing T cells in mice with noncontact fluorescence molecular tomography. Mol Imaging 6(2):96-107.
Gregoriou GG, Luppino G, Matelli M, Savaki HE (2005) Frontal cortical areas of the monkey brain engaged in reaching behavior: a (14) C-deoxyglucose imaging study. Neuroimage 15;27(2):442-64.
Gyftocostas D (1983) The mechanism of intermittent claudication in the calf of human being in case of superficial femoral artery obstraction. Doctoral thesis. Kapodistrian University of Athens Medical School, pp. 15-46.
Gazouli M, Bouziotis P, Lyberopoulou A, Ikonomopoulos J, Papalois A, Anagnou NP, Efstathopoulos EP (2014) Quantum dots-bevacizumab complexes for in vivo imaging of tumors. In Vivo 28(6):1091-5.
Gouletsou PG, Amiridis GS,Cripps PJ, Lainas T, Deligiannis K, Saratsis P, Fthenakis GC (2003) Ultrasonographic appearance of clinically healthy testicles and epididymides of rams. Theriogenology 59(9):1959-72.
Gouletsou PG, Galatos AD, Leontides LS (2008) Comparison between ultrasonographic and caliper measurements of testicular volume in the dog. Anim Reprod Sci 108(1-2):1-12.
Gouletsou PG, Galatos AD, Fthenakis GC (2008) Clinical, ultrasonographic and pathological features following unilateral vasectomy in rams. Anim Reprod Sci 103(1-2):52-68.
Hanna-Marja Voipio, Baneux P, Gomez de Segura I A, Hau J, Wolfensohn S (2008) Guidelines for the veterinary care of laboratory animals: report of the FELASA/ECLAM/ESLAV Joint Working Group on Veterinary Care Members of the Joint Working Group on Veterinary Care. Lab Anim 42:1-11.
Kagadis GC, Spyridonos P, Karnabatidis D, Diamantopoulos A, Athanasiadis E, Daskalakis A, Katsanos K, Cavouras D, Mihailidis D, Siablis D, Nikiforidis GC (2008) Computerized analysis of digital subtraction angiography: a tool for quantitative in-vivo vascular imaging. J Digit Imaging 21(4):433-45.
Κalogeropoulou C (1998) Evaluation of the blood flow in splachnic circulation with color Doppler: Experimental and clinical study. Doctoral thesis. School of Medicine, University of Patras. Laboratory of radiology pp. 13-65.
Κarnabatidis D (2001) Evaluation of the micro - vessels of the chick embryo chorioallantoic membrane and tumors implanted in rats by digital subtraction angiography. Doctoral thesis. School of Medicine, University of Patras. Laboratory of radiology pp. 22-96.
Kasapas K, Diamantopoulou A, Pentilas N, Papalois A, Douzinas E, Kouraklis G, Slama M, Terkawi AS, Blaivas M, Sargsyan AE, Karakitsos D (2014) Invasive and ultrasound based monitoring of the intracranial pressure in an experimental model of epidural hematoma progressing towards brain tamponade on rabbits. SciWorldJ 2014:504248.
Kitrou PM, Spiliopoulos S, Katsanos K, Tsantis S, Diamantopoulos A, Kallidonis P, Kyriakopoulou M, Kagadis GC, Karnabatidis D, Siablis D (2014) Venous drug-eluting vs. bare-metal stenting: an experimental animal study using frequency domain optical coherence tomography. Hellenic J Cardiol 55(5):386-92.
Kyrkos MJ, Papavasiliou KA, Kenanidis E, Tsiridis E, Sayegh FE, Kapetanos GA (2003) Calcitonin delays the progress of early-stage mechanically induced osteoarthritis. In vivo, prospective study. Osteoarthritis Cartilage 21(7):973-80.
Mantis P, Tontis D, Church D, Lloyd D, Stevens K, Balomenos D, Gouletsou PG, Gianoulopoulos G, Doukas D, Galatos AD, Saridomichelakis M (2014) High-frequency ultrasound biomicroscopy of the normal canine haired skin. Vet Dermatol 25(3):176-81
Maris TG, Prassopoulos P, Papanikolaou N, Christodoulou P, Doxas PG, Helidonis ES, Gourtsoyiannis N (2002) Transtympanic iontophoresis with a biocompatible paramagnetic solution at MR imaging: experimental feasibility study in rabbits. Radiology 223(3):689-94.
Mavrogianni VS, Fthenakis GC, Burriel AR, Gouletsou P, Papaioannou N, Taitzoglou IA (2004) Experimentally induced teat stenosis in dairy ewes: clinical, pathological and ultrasonographic features. J Comp Pathol 130(1):70-4.
Papadakis Ε (1995) Effects of ionizing radiation on the healing progress of the post-extraction wound. Doctoral thesis. Kapodistrian University of Athens Dental School Laboratory of radiology, pp. 20-99.
Papadopoulos MA, Jannowitz C, Boettcher P, Henke J, Stolla R, Zeilhofer HF, Kovacs L, Erhardt W, Biemer E, Papadopulos NA (2005) Threedimensional fetal cephalometry: an evaluation of the reliability of cephalometric measurements based on three-dimensional CT reconstructions and on dry skulls of sheep fetuses. J Craniomaxillofac Surg 33(4):229-37.
Papadopoulos MA, Papadopulos NA, Jannowitz C, Boettcher P, Henke J, Stolla R, Zeilhofer HF, Kovacs L, Biemer E (2006) Threedimensional cephalometric evaluation of maxillary growth following in utero repair of cleft lip and alveolar-like defects in the mid-gestational sheep model. Fetal Diagn Ther 21(1):105-14.
Papadopoulou P (2008) The lymph drainage of the mammary glands in the cat: a lymphographic and computed tomography – lymphographic study. Doctoral thesis. Aristotelian University of Athens Veterinary Faculty Surgical Clinic, pp 20-60.
Papadopoulou PL, Patsikas MN, Charitanti A, Kazakos GM, Papazoglou LG, Karayannopoulou M, Chrisogonidis I, Tziris N, Dimitriadis A (2009) The lymph drainage pattern of the mammary glands in the cat: a lymphographic and computerized tomography lymphographic study. Anat Histol Embryol 38(4):292-9.
Patsikas M (1992) Lymphangiographic study of the lymph drainage of mammary glands in the bitch. Doctoral thesis. Aristotelian University of Athens Veterinary Faculty Surgical Clinic, pp 3-65.
Patsikas MN, Dessiris AK (1996) The lymph drainage of the mammary glands in the bitch: a lymphographic study. Part I: The 1st, 2nd, 4th and 5th mammary glands. Anat Histol Embryol 25(2):131-8.
Patsikas MN, Koutinas A, Vlemas I, Polizopoulou Z, Moustardas N, Tzegas S, Dessiris AK (1999) Absence of cerebrospinal fluid abnormalities and spinal cord lesions after iotrolan cervical myelography in normal cats: an open placebo-controlled study. Zentralbl Veterinarmed A 46(8):453-7.
Patsikas MN, Polizopoulou Z, Koutinas A, Galatos A, Moustardas N, Tzegas S, Dessiris AK (1999) Absence of postmyelographic adverse effects and high radiographic resolution of iotrolan used in the cervical myelography for the clinically normal cat: an open-placebo controlled study. Zentralbl Veterinarmed A 46(2):69-74.
Patsikas MN, Papazoglou LG, Papaioannou NG, Savvas I, Kazakos GM, Dessiris AK (2003) Ultrasonographic findings of intestinal intussusception in seven cats. J Feline Med Surg. 5(6):335-43.
Patsikas MN, Jakovljevic S, Moustardas N, Papazoglou LG, Kazakos GM, Dessiris AK (2003) Ultrasonographic signs of intestinal intussusception associated with acute enteritis or gastroenteritis in 19 young dogs. J Am Anim Hosp Assoc 39(1):57-66.
Patsikas MN, Papazoglou LG, Papaioannou NG, Dessiris AK (2004) Normal and abnormal ultrasonographic findings that mimic small intestinal intussusception in the dog. J Am Anim Hosp Assoc 40(2):147-51.
Patsikas MN, Papazoglou LG, Jakovljevic S, Dessiris AK (2005) Color Doppler ultrasonography in prediction of the reducibility of intussuscepted bowel in 15 young dogs. Vet Radiol Ultrasound 46(4):313-6.
Patsikas MN, Karayannopoulou M, Kaldrymidoy E, Papazoglou LG, Papadopoulou PL, Tzegas SI, Tziris NE, Kaitzis DG, Dimitriadis AS, Dessiris AK (2006) The lymph drainage of the neoplastic mammary glands in the bitch: a lymphographic study. Anat Histol Embryol 35(4):228-34.
Polizopoulou ZS, Koutinas AF, Souftas VD, Kaldrymidou E, Kazakos G, Papadopoulos G (2004) Diagnostic correlation of CT-MRI and histopathology in 10 dogs with brain neoplasms. J Vet Med A Physiol Pathol Clin Med 51(5):226-31.
Raos V, Kilintari M, Savaki HE (2014) Viewing a forelimb induces widespread cortical activations. Neuroimage 89:122-42.
Savaki Η, Dalezios Y (1999) 14C-deoxyglucose mapping of the monkey brain during reaching to visual targets. Prog Neurobiol 58(6):473-540.
Stasinopoulou M, Mantziaras G, Paronis E, Balafas E, Lelovas P, Samara A, Kostomitsopoulos N (2014) Use of real-time ultrasonography as an alternative method for early detection, confirmation and evaluation of rat pregnancy. Ultrasound Med Biol 40(6):1372-8.
Sokolis DP, Boudoulas H, Kavantzas NG, Kostomitsopoulos N, Agapitos EV, Karayannacos PE (2002) A morphometric study of the structural characteristics of the aorta in pigs using an image analysis method Anat Histol Embryol. 31(1):21-30.
Tzaphlidou M, Fountos G, Glaros D (2000) Bone hydroxyapatite/collagen ratio. In vivo measurements by X-ray absorptiometry. Ann N Y Acad Sci 904:284-6.
Tzaphlidou M, Speller R, Royle G, Griffiths J (2006) Preliminary estimates of the calcium/phosphorus ratio at different cortical bone sites using synchrotron microCT. Phys Med Biol 7;51(7):1849-55.
Vavuranakis M, Papaioannou TG, Kakadiaris IA, O’Malley SM, Naghavi M, Filis K, Sanidas EA, Papalois A, Stamatopoulos I, Stefanadis C (2007) Detection of perivascular blood flow in vivo by contrastenhanced intracoronary ultrasonography and image analysis: an animal study. Clin Exp Pharmacol Physiol 34(12):1319-23.
Ypsilantis P, Deftereos S, Prassopoulos P, Simopoulos C (2009) Ultrasonographic diagnosis of pregnancy in rats. J Am Assoc Lab Anim Sci 48(6):734-9.
Am häufigsten gelesenen Artikel dieser/dieses Autor/in