Impact of a porcine reproductive and respiratory syndrome inactivated vaccine on the health and semen traits of boars

Published: Nov 10, 2017
PRRS vaccine semen fertility boar

The aim of this study was to investigate the effects of a commercial European Porcine Reproductive and Respiratory Syndrome (PRRS) - inactivated vaccine on health status, semen characteristics and semen fertilizing capacity in vivo of boars. In a farrow to finish farm that suffered from chronic course of PRRS, 7 donor boars (1.1-2.2 years old) were initially twice vaccinated, with a 4 weeks interval. At the same time, all gilts / sows of the herd were, also, vaccinated. Boars were monitored for abnormal clinical signs 24 h prior to 15 days after each vaccination. Ejaculates were collected 24 h prior, 24 h after and 15 days after each vaccination and the semen characteristics were evaluated. A total of 305 sows were inseminated twice with the collected semen 2 weeks prior up to 6 weeks after the 1st vaccination. No systemic clinical signs and significant differences in semen characteristics, except of sperm viability, were noticed. After the 1st vaccination, sperm viability increased, but this was probably due to the increase of the age of 7 boars during the trial and not due to the vaccination. All semen characteristics were decreased 24h after each vaccination, but they were not lower than the value of accepted criteria semen quality. No change was noticed in sow's fertility parameters, apart from the farrowing rate, that was not, however, of clinical importance. In conclusion, the use of a PRRSV - inactivated vaccine in boars is safe and has not negative effects on health status and their semen characteristics neither on fertilizing capacity in vivo.

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Britt JH, Almond GW, Flowers WL (1999). Diseases of the Reproductive System. In: Diseases of Swine. Straw BE, D'Allaire S, Mengeling WL, Taylor DJ, eds. 8th ed., Iowa State University Press, Ames, Iowa: pp. 898-911.
Cavanagh D (1997). Nidovirales: a new order comprising Coronaviridae and Arteriviridae. Arch Virol 142: 629-633.
Christopher-Hennings J, Nelson EA, Nelson JK, and Benfield DA (1997). Effects of a modified-live virus vaccine against porcine reproductive and respiratory syndrome in boars. Am J Vet Res 58:40-45.
European Agency for the evaluation of medicinal products (1998). Guideline on Good Clinical Practices. EMEA/CVMP/595/98. London UK.
Federation of Veterinarians of Europe (FVE) (2001). Code of Good Veterinary Practice (GVP Code): pp. 4-7.
Flowers WL (1997). Artificial Insemination in Swine. In: Current Therapy in Large Animal Theriogenology. Youngquist RS ed. WB Saunders Company: pp. 678-683.
Houston DM and Radostits OM (2000). The Clinical Examination In: Veterinary Clinical Examination and Diagnosis. Radostits OM, Mayhew IG, Houston DM, eds. WB Saunders Company: pp. 91-124.
Lager KM, Mengeling WL, Brockmeier SL (1996). Effect of post-coital intrauterine inoculation of porcine reproductive and respiratory syndrome virus on conception in gilt. Vet Ree 138(10): 227-228.
Leiding C (2000). Prevention of Disease Transmission by the Use of Semen in the Porcine AI Industry. Liv Product Sci 62: 221-236.
Meulenberg JJ, Petersen den Besten A, de Kluyver E, van Nieuwstadt A, Wensvoort G, Moormann RJ (1997). Molecular haracterization of Lelystad virus Vet Microbiol 55:197-202.
Muelenberg JM, Hülst MM, de Meijer EJ, Moonen PL, den Besten A,de Kluyver EP, Wensvoort G and Moormann RJ (1993). Lelystad virus, the causative agent of porcine epidemic abortion and respiratory syndrome (PEARS) is related to LDV and EAV. Virology 19:62-74.
Nielsen TL, Nielsen J, Have P, Baekbo P, Hoff-Jorgensen R and Botner A (1997). Examination of virus shedding in semen from vaccinated and from previously infected boars after experimental challenge with porcine reproductive and respiratory syndrome virus. Vet Microbiol 54:101-112.
Organization for Economic Co-operation and Development (OECD) (1998). Series on Principles of Good Laboratory Practice (GLP) and Compliance Monitoring, Organization for Economic Cooperation and Development, Paris, France: pp. 2-41.
Papatsiros VG, Alexopoulos C, Kritas SK, Koptopoulos G, Nauwynck HJ, Pensaert MB and Kyriakis SC (2006). Long-term administration of a commercial porcine reproductive and respiratory syndrome virus (PRRSV)-inactivated vaccine in PRRSV-endemically infected sows. J Vet Med B, Infect Dis Vet Public Health 53: 266-272.
Prieto C, Sanchez R, Martin-Rillo S, Suarez P, Simarro I, Solana A, and Castro JM (1996a). Exposure of gilts in early gestation to porcine reproductive and respiratory syndrome virus. Vet Ree 138(22): 536-539.
Prieto C, Suarez P, Bautista JM, Sanchez R, Rillo SM, Simarro I, Solana A, and Castro JM (1996b). Semen changes in boars after experimental infection with porcine reproductive and respiratory syndrome (PRRS) virus. Theriogenology 45: 383-395.
Prieto C, Suarez P, Simarro I, Garcia C, Martin-Rillo S, Castro JM (1996c). Effect of porcine reproductive and respiratory syndrome virus (PRRSV) on development of porcine fertilized ova in vitro. Theriogenology 46 (4): 687-693.
Swenson SL, Hill HT, Zimmerman JJ, Evans LE, Landgraf JG, Wills RW. Sanderson TP, McGinley MJ, Brevik AK, Ciszewski DK, and Frey ML (1994). Excretion of porcine reproductive and respiratory syndrome virus in semen after experimentally induced infection in boars. J Am Vet Med Assoc 204:1943-1948.
Swenson SL, Hill HT, Zimmerman JJ, Evans LE, Wills RW, Yoon KJ, Schwartz KJ, Althouse GC, McGinley MJ and Brevik AK (1995). Preliminary assessment of an inactivated PRRS virus vaccine on the excretion of virus in semen. Swine Health Product 3: 244-247.
Tizard IR (2004). The Use of Vaccines. In: Veterinary Immunology, An Introduction. Tizard IR ed. 7th ed. WB Saunders Company, Philadelphia: p. 265.
Vilaca KJ, Dewey C, Pettitt M and Friendship R (2001). The effects of a PRRS vaccine on the semen quality of boars In: Proceedings of 32th American Association of Swine Veterinarians Meeting, Nashville, Tennessee, USA, 32: pp. 59-61.
Vilaca KJ, Dewey C, Friendship R, Plante C, Buhr MM (2003). Semen quality parameters in naïve boars vaccinated with a MLV porcine reproductive and respiratory syndrome virus vaccine. In: Proceedings of 34th American Association of Swine Veterinarians, Orlando, Florida 32: pp. 25-26.
Yaeger MJ, Prieve T, Collins J, Christopher-Hennings J, Nelson E, and Benfield D (1993). Evidence for the transmission of porcine reproductive and respiratory syndrome (PRRS) virus in boar semen. Swine Health Product 1(5): 7-9.
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