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Porcine malignant hyperthermia during sevoflurane anaesthasia

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N. G. KOSTOMITSOPOULOS (Ν.Γ. ΚΩΣΤΟΜΗΤΣΟΠΟΥΛΟΣ), E. BALAFAS (Ε. ΜΠΑΛΑΦΑΣ), G. MANGIARAS (Γ. ΜΑΝΤΖΙΑΡΑΣ), E. PARONIS (Ε. ΠΑΡΩΝΗΣ), P. ALEXAKOS (Π. ΑΛΕΞΑΚΟΣ), P. E. KARAYANNAKOS (Π.Ε. ΚΑΡΑΓΙΑΝΝΑΚΟΣ)
N. G. KOSTOMITSOPOULOS (Ν.Γ. ΚΩΣΤΟΜΗΤΣΟΠΟΥΛΟΣ), E. BALAFAS (Ε. ΜΠΑΛΑΦΑΣ), G. MANGIARAS (Γ. ΜΑΝΤΖΙΑΡΑΣ), E. PARONIS (Ε. ΠΑΡΩΝΗΣ), P. ALEXAKOS (Π. ΑΛΕΞΑΚΟΣ), P. E. KARAYANNAKOS (Π.Ε. ΚΑΡΑΓΙΑΝΝΑΚΟΣ)

Abstract


During a surgical procedure, in a pig, under general anaesthesia with sevoflurane, the animal developed malignant hyperthermia. Malignant hyperthermia was expressed only by a progressive increase of rectal temperature without early symptoms from the cardiopulmonary system. The delayed onset of the malignant hyperthermia may be due to the co-administration of a number of drugs at the pre-anaesthetic phase as well as during the surgical procedure.


Keywords


malignant hyperthermia; pig; sevoflurane; anaesthesia

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References


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Copyright (c) 2017 N. G. KOSTOMITSOPOULOS, E. BALAFAS, G. MANGIARAS, E. PARONIS, P. ALEXAKOS, P. E. KARAYANNAKOS