Porcine malignant hyperthermia during sevoflurane anaesthasia


Published: Nov 27, 2017
Keywords:
malignant hyperthermia pig sevoflurane anaesthesia
N. G. KOSTOMITSOPOULOS (Ν.Γ. ΚΩΣΤΟΜΗΤΣΟΠΟΥΛΟΣ)
E. BALAFAS (Ε. ΜΠΑΛΑΦΑΣ)
G. MANGIARAS (Γ. ΜΑΝΤΖΙΑΡΑΣ)
E. PARONIS (Ε. ΠΑΡΩΝΗΣ)
P. ALEXAKOS (Π. ΑΛΕΞΑΚΟΣ)
P. E. KARAYANNAKOS (Π.Ε. ΚΑΡΑΓΙΑΝΝΑΚΟΣ)
Abstract

During a surgical procedure, in a pig, under general anaesthesia with sevoflurane, the animal developed malignant hyperthermia. Malignant hyperthermia was expressed only by a progressive increase of rectal temperature without early symptoms from the cardiopulmonary system. The delayed onset of the malignant hyperthermia may be due to the co-administration of a number of drugs at the pre-anaesthetic phase as well as during the surgical procedure.

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