The Effect of Omega 3 and Vitamin E against Avian Influenza in Broiler Chickens

PDF
Published: Jan 29, 2018
DOI: https://doi.org/10.12681/jhvms.15491
Keywords:
Antibody titer FCR H/R ratio Histopathology
M. TASEER
Department of Pathology, University of Veterinary and Animal Sciences
A. ASLAM
Department of Pathology, University of Veterinary and Animal Sciences
Z. I. CHAUDHARY
Department of Pathology, University of Veterinary and Animal Sciences
K. ASHRAF
Department of Parasitology, University of Veterinary and Animal Sciences
R. AKHTAR
Department of Pathology, University of Veterinary and Animal Sciences
G. MUSTAFA
Department of Pathology, University of Veterinary and Animal Sciences
Abstract

The present study assessed the individual and combined effect of vitamin E and omega 3 against low pathogenic avian influenza (LPAI) virus in broiler birds. Day-old broiler birds (n=125) were equally divided into five groups (A, B, C, D & E). Group A was non infected negative control. While groups B, C, D and E were infected with low pathogenic avian influenza (H9N2) virus at 28th day (2 HAunits/bird). Group B was given omega 3 at rate of 150mg/kg in feed. Group C was given vitamin E 200 IU/kg. Group D was offered vitamin E and omega 3. Group E was designated as positive control without supplementation. The results revealed significantly increased antibody titer, decreased heterophil lymphocyte ratio, improved feed conversion ratio and least histopathological lesions in birds given vitamin E alone followed by the group given combination of vitamin E and omega 3. These results concluded the positive impact of Vitamin E as compare to omega 3 alone and combined omega 3 with vitamin E against LPAI infection in broiler chickens. These findings can have useful field application in control of avian influenza.

Article Details
  • Section
  • Research Articles
Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Authors who publish with this journal agree to the following terms:

· Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution Non-Commercial License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.

· Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g. post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.

· Authors are permitted and encouraged to post their work online (preferably in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.

Downloads
Download data is not yet available.
References
Al-Garib S, Agha A, Al-Mesilaty L (2016) Low pathogenic avian influenza H9N2: world-wide distribution. World Poultry Sci J 72:125-136
Barbour EK, Yaghi RH, Shaib HA, Tayeb IT, Sleiman FT (2008) Evaluation of an essential oil in treatment of immunosuppressedcoinfected broilers. AEJSA 2:212-218.
Gogos AC, Ginopoulos P, Salsa B, Apostolidou E, Zoumbos NC, Kalfarentzos F (1998) Dietary omega-3 polyunsaturated fatty acids plus vitamin E restore immunodeficiency and prolong survival for severely ill patients with generalized malignancy. Cancer 82: 395-402.
De-Rosa V, Galgani M, Santopaolo M, Colamatteo A, Laccetti R, Matarese G (2015) Nutritional control of immunity: Balancing the metabolic requirements with an appropriate immune function. SemImmunol27: 300-309.
Hagenaars TJ, Fischer EAJ, Jansen CA, Rebel JMJ, Spekreijse D, Vervelde L, Backer JA, de Jong MCM, Koets AP (2016) Modelling the innate immune response against avian influenza virus in chicken. PLoS ONE 11: e0157816. doi:10.1371/journal. pone.0157816.
Meydani SN, Barklund MP, Liu S, Meydani M, Miller RA, Cannon JG, Morrow FD, Rocklin R, Blumberg JB (1990) Vitamin E supplementation enhances cell-mediated immunity in healthy elderly subjects. Am J C/in Nuir 52:557-563.
Mo I, Brugh M, Fletcher O, Rowland G, Swayne D(1997) Comparative pathology of chickens experimentally inoculated with avian influenza viruses of low and high pathogenicity. Avian Dis 41:125-136.
Muller C, Jenni Eiermann S, Jenni L (2011) Heterophils/Lymphocytes ratio and circulating corticosterone do not indicate the same stress imposed on Eurasian kestrel nestlings. Funct Ecol 25:566-576.
Pedersen JC (2008) Hemagglutination-inhibition test for avian influenza virus subtype identification and the detection and quantitation of serum antibodies to the avian influenza virus. Methods MolBiol436:53-66.
Most read articles by the same author(s)