Field evaluation of a live vaccine against porcine reproductive and respiratory syndrome in fattening pigs


Published: Jan 31, 2018
Keywords:
PRRS live vaccine
J. MAVROMATIS (Ι. ΜΑΥΡΟΜΜΑΤΗΣ)
S. K. KRITAS (Σ.Κ. ΚΡΗΤΑΣ)
C. ALEXOPOULOS (Κ. ΑΛΕΞΟΠΟΥΛΟΣ)
A. TSINAS (Α. ΤΣΙΝΑΣ)
S. C. KYRIAKIS (Σ.K. ΚΥΡΙΑΚΗΣ)
Abstract
In this study, a live vaccine based on an European isolate of porcine reproductive and respiratory syndrome (Porcilis PRRS, Intervet) virus has been tested in order to determine the protection of fattening pigs against the respiratory form of the syndrome under field conditions. Ten thousand pigs in an infected farm were vaccinated against PRRS virus at the age of 6 weeks and were compared to non-vaccinated pigs with respect to their health status, mortality, performance parameters (average daily gain, average daily feed intake, feed conversion ratio) and the presence of specific pathogens in their lungs. The results have shown that treated pigs became less frequently sick and have demonstrated reduced mortality compared to untreated ones. As compared to non-vaccinated animals, PRRSvaccinated pigs also performed in a better way with respect to feed conversion ratio (P<0.05) and average daily gain (P<0.05), while feed intake was similar for both groups (P>0.05). Bacteriological examinations of the lungs have revealed increased incidence of respiratory bacterial infection in untreated pigs compared to treated ones. Also a tendency for faster antibody response was detected in the vaccinées. Finally, no clinical side effects were observed after the administration of the vaccine. The results of the present study show that immunization with Porcilis PRRS (Intervet) does protect fattening pigs against the respiratory manifestations of PRRS.
Article Details
  • Section
  • Research Articles
Downloads
Download data is not yet available.
References
Meredith Μ J. Porcine reproductive and respiratory syndrome (PRRS). Pig Disease Information Centre, University of Cambridge. Publisher: Boehringer Ingelheim, 1995
Dee SA, Morrison RB, Joo HS. Eradicating porcine reproductive and respiratory syndrome (PRRS) virus using two-site production and nursery depopulation. Swine Health and Production, 1993,1: 20-23
Dee SA, Joo HS, Poison DD, Park BK, Pijoan C, Molitor TW, Collins JE, King V. Evaluation of the effects of nursery depopulation on the persistence of porcine reproductive and respiratory syndrome virus and the productivity of 34 farms. Vet Ree, 1997,140:247-248
Kritas SK, Mavromatis J, Kostoglou P, Varoudis L, Kyriakis SC. Field experience with the use of a new vaccine on natural occurring outbreaks of porcine reproductive and respiratory syndrome (PRRS). Abstracts of the Second International Symposium on Porcine reproductive and respiratory syndrome (PRRS), Copenhagen, Denmark, 1995, pp 35
Plana Duran J, Basions M, Urniza A, Vayreda M, Vila X, Mane H. Efficacy of an inactivated vaccine for prevention of reproductive failure induced by porcine reproductive and respiratory syndrome virus. Vet Microbiol, 1997,55:361-370
Gorcyca D, Schlesinger Κ, Chladek D, Behan W. RespPRRS: a new tool for the prevention and control of PRRS in pigs. Proceedings of 26th annual meeting of American Association of Swine Practitioners, Omaha, Nebraska, March 4-7,1995, pp. 1-22
Botner A, Strandbygaard Β, Sorensen KJ, Have P, Madsen KG, Madsen ES, Alexandersen S. Appearance of acute PRRS-like symptoms in sow herds after vaccination with a modified live PRRS vaccine. Vet Ree, 1997,141: 497-499
Plomgaard J. PRRS situation takes a turn in Denmark. International Pigletter, 1997,17:37-38
Wensvoort G, de Kluyver EP, Luijtze EA, Besten Α., den Harris L, Collins JE, Christianson WT, Chladec D. Antigenic comparison of Lelystad virus and swine infertility and respiatory syndrome (SIRS) virus. J Vet Diagn Invest, 1992, 4:134-138.
Murakami Y, Kato A, Tsuda T, Morozumi T, Miura Y, Sugimura T. Isolation and serological characterization of porcine reproductive and respiratory syndrome (PRRS) viruses from pigs with reproductive and respiratory disorders in Japan. J Vet Med Sci, 1994,56: 891-894
Magar R, Larochelle R, Dea S, Gagnon CA, Nelson EA, Christopher-Hennings J, Benfield DA. Antigenic comparison of Canadian and US isolates of porcine reproductive and respiratory syndrome virus using monoclonal antibodies to the nucleocapsid protein. Can J Vet Res, 1995,59: 232-234
Dea S, Gagnon CA, Mardassi H, Milane G. Antigenic variability among North American and European strains of porcine reproductive and respiratory syndrome virus as defined by monoclonal antibodies to the matrix protein. J. Clin. Microbiol, 1996,34:1488-1493
Sornsen SA, Zimmerman JJ, Poison DD, Roof MB. Effect of PRRS vaccination on average daily gain: A comparison of intranasal and intranasal-intramuscular administration. Swine Health and Production, 1998, 6:13-19
Van Reeth K, Koyen A, Pensaert M. Clinical effects of dual infections with porcine epidemic abortion and respiratory syndrome virus, porcine Coronavirus and swine influenza virus. Proceedings 13th IPVS. Thailand, 1994, pp. 51
Carvalho LF, Segales J, Pijoan C. Effect of PRRS on subsequent Pasteurella multocida challenge in pigs. Abstracts of the Second International Symposium on Porcine reproductive and respiratory syndrome (PRRS), Copenhagen, Denmark, 1995, pp. 20
Pol J, Van Leengoed L, Stockhofe Ν, Wensvoort G. Dual infections of PRRS/influenza or PRRS/APP in the respiratory tract. Abstracts of the Second International Symposium on Porcine reproductive and respiratory syndrome (PRRS),
Copenhagen, Denmark, 1995, pp. 22
Solano G, Segales J, Pijoan C. Interaction between porcine reproductive and respiratory syndrome virus (PRRSv) and Haemophilus parasuis. Abstracts of the Second International Symposium on Porcine reproductive and respiratory syndrome (PRRS), Copenhagen, Denmark, 1995, pp. 21
Papatsas IC, Kyriakis SC, Papadopoulos O, Sarris KJ, Lekkas S. Intradermal vaccination against Pseudorabies virus and swine influenza in growing/finishing pigs. Swine Health and Production, 1996,4: 279-285
Buttery P. Growth promotion in animals - an overview. In: Livestock productivity enchancers: An economic assessment. CAB Int., UK, 1993: 7-23
Most read articles by the same author(s)