Infection of fattening pigs by a virulent strain of Aujeszky's disease virus and its spread in the pig
Abstract
In this paper, the spread of the virulent 75V19 strain of Aujeszky's disease virus (ADV) in fattening pigs has been examined, and the association of this parameter to the development of relative symptoms has being sought. Four fattening pigs without antibodies against ADV have been oronasally inoculated by instillation of 1075 TCID50 of the infective strain, whilst another four seronegative pigs have been infected by the same dose of the strain administered in aerosol form. The pigs were euthanised at 4 days post inoculation and their tissues were examined by virus isolation and quantification in cell cultures. An extended spread of the virus was seen with both inoculation methods. However, the nasopharyngeal mucosa, the diaphragmatic lobes of the lungs and the pulmonary macrophages were more extensively infected in aerosol inoculated pigs compared to those of the other group. No difference was observed as regards the appearance of clinical disease between the two groups of fattening pigs. The results have also shown that, despite the high replication rate of ADV in the nasal mucosa and its ability to invade the central nervous system of fattening pigs, the degree of its replication in the nervous tissue in these pigs is limited when compared to suckling pigs.
Article Details
- How to Cite
-
KRITAS (Σ.Κ. ΚΡΗΤΑΣ) S. K., NAUWYNCK, H. J., PENSAERT, M. B., & KYRIAKIS (Σ.Κ. ΚΥΡΙΑΚΗΣ) S. C. (2018). Infection of fattening pigs by a virulent strain of Aujeszky’s disease virus and its spread in the pig. Journal of the Hellenic Veterinary Medical Society, 50(4), 310–314. https://doi.org/10.12681/jhvms.15727
- Issue
- Vol. 50 No. 4 (1999)
- Section
- Research Articles
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Authors who publish with this journal agree to the following terms:
· Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution Non-Commercial License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
· Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g. post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
· Authors are permitted and encouraged to post their work online (preferably in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.
