Influence of Mycostop Mycotoxin Adsorbents on Production, Oxidative Stress, and Economic Cost of Laying Hens Intoxicated with T-2 Toxin

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Δημοσιευμένα: Jan 16, 2025
DOI: https://doi.org/10.12681/jhvms.37778
N Puvača
University Business Academy, Faculty of Economics and Engineering Management, Department of Engineering Management in Biotechnology
https://orcid.org/0000-0002-5500-7010
T Shtylla Kika
Faculty of Economics and Engineering Management in Novi Sad, University Business Academy in Novi Sad, Cvećarska 2, 21000 Novi Sad, Serbia
I Brkić
Faculty of Economics and Engineering Management in Novi Sad, University Business Academy in Novi Sad, Cvećarska 2, 21000 Novi Sad, Serbia
D Ljubojević Pelić
Scientific Veterinary Institute “Novi Sad”, Rumenački put 20, 21000 Novi Sad, Serbia
V Tufarelli
Department of Precision and Regenerative Medicine and Jonian Area (DiMePRe-J), Section of Veterinary Science and Animal Production, University of Bari Aldo Moro, 70010 Valenzano, Italy
N Nikolova
Institute of Animal Science, Skopje, University “Ss. Cyril and Methodius”, North Macedonia
B Kostić
Faculty of Economics and Engineering Management in Novi Sad, University Business Academy in Novi Sad, Cvećarska 2, 21000 Novi Sad, Serbia
I Radojičić
INBERG d.o.o., Braće Iker 74, 11275 Boljevci, Serbia
S Brkanlić
Faculty of Economics and Engineering Management in Novi Sad, University Business Academy in Novi Sad, Cvećarska 2, 21000 Novi Sad, Serbia
V Bursić
Faculty of Agriculture, University of Novi Sad, Trg Dositeja Obradovića 8, 21000 Novi Sad, Serbia
Περίληψη

Mycotoxin contamination in poultry feed poses a significant threat to both production performance and animal health. Among various mycotoxins, the T-2 toxin stands out as particularly detrimental to laying hens, leading to decreased productivity and increased oxidative stress. This study aimed to evaluate the efficacy of two mycotoxin adsorbents, Mycostop Premium 2.0 and Mycostop Supreme, at a concentration of 2 kg/t of feed, in mitigating the adverse effects of T-2 toxin on laying hens' production performance, nutritive and physical egg quality, oxidative stress levels, the occurrence of oral and tongue lesions, and economic cost of production. A total of 200 laying hens were randomly allocated to four dietary treatments: control T1 (basal diet without T-2 toxin or mycotoxin adsorbents), T2 (basal diet contaminated with 8 mg/kg of T-2 toxin), T3 (basal diet contaminated with 8 mg/kg of T-2 toxin and 2kg/t of feed Mycostop Premium 2.0), and T4 (basal diet contaminated with 8 mg/kg of T-2 toxin and 2kg/t of feed Mycostop Supreme). The trial lasted for 56 days, during which production performance parameters, including feed intake, egg production, egg weight, and feed conversion ratio, were monitored. Additionally, nutritive and physical egg quality traits, such as shell strength, yolk color, albumen height, and Haugh unit, were assessed. Oxidative stress biomarkers, including malondialdehyde (MDA) levels, antioxidant enzyme activities, and total antioxidant capacity, were measured to evaluate the impact of mycotoxin adsorbents on oxidative stress levels in laying hens. Furthermore, the occurrence and severity of oral and tongue lesions were recorded to assess the potential protective effects of Mycostop Premium 2.0 and Mycostop Supreme against mycotoxin-induced oral health complications. In conclusion, findings of this research highlight the potential of mycotoxin adsorbents as valuable tools for safeguarding poultry health and optimizing productivity in mycotoxin-challenged environments.

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Βιογραφικό Συγγραφέα
N Puvača, University Business Academy, Faculty of Economics and Engineering Management, Department of Engineering Management in Biotechnology

Department of Engineering Management in Biotechnology

Full Professor

Αναφορές
Adhikari, M., Negi, B., Kaushik, N., Adhikari, A., Al-Khedhairy, A. A.,
Kaushik, N. K., & Choi, E. H. (2017). T-2 mycotoxin: Toxicological
effects and decontamination strategies. Oncotarget, 8(20), 33933-
https://doi.org/10.18632/oncotarget.15422
Altmann, B. A., Trinks, A., & Mörlein, D. (2023). Consumer preferences
for the color of unprocessed animal foods. Journal of Food Science,
(3), 909-925. https://doi.org/10.1111/1750-3841.16485
Bócsai, A., Ancsin, Zs., Fernye, Cs., Zándoki, E., Szabó-Fodor, J., Erdélyi,
M., Mézes, M., & Balogh, K. (2015). Dose-dependent short-term effects
of T-2 toxin exposure on lipid peroxidation and antioxidant parameters
of laying hens. European Poultry Science (EPS), 79. https://
doi.org/10.1399/eps.2015.115
Brink, M., Janssens, G. P. J., Demeyer, P., Bağci, Ö., & Delezie, E. (2022).
Reduction of dietary crude protein and feed form: Impact on broiler
litter quality, ammonia concentrations, excreta composition, performance,
welfare, and meat quality. Animal Nutrition, 9, 291-303.
https://doi.org/10.1016/j.aninu.2021.12.009
Chowdhury, S. R., & Smith, T. K. (2004). Effects of feeding blends of
grains naturally contaminated with Fusarium mycotoxins on performance
and metabolism of laying hens. Poultry Science, 83(11), 1849-
https://doi.org/10.1093/ps/83.11.1849
Chukwuka, O. K., Okoli, I. C., Okeudo, N. J., Udedibie, A. B. I., Ogbuewu,
I. P., Aladi, N. O., Iheshiulor, O. O. M., & Omede, A. A.
(2010). Egg Quality Defects in Poultry Management and Food Safety.
Asian Journal of Agricultural Research, 5(1), 1-16. https://doi.
org/10.3923/ajar.2011.1.16
Čolović, R., Puvača, N., Cheli, F., Avantaggiato, G., Greco, D., Đuragić,
O., Kos, J., & Pinotti, L. (2019). Decontamination of Mycotoxin-
Contaminated Feedstuffs and Compound Feed. Toxins, 11(11),
https://doi.org/10.3390/toxins11110617
de Oliveira, C. A. F., de Neeff, D. V., de Pinho Carão, Á. C., & Corassin,
C. H. (2017). Mycotoxin Impact on Egg Production. In P. Y. Hester
(Ed.), Egg Innovations and Strategies for Improvements (pp. 581-
. Academic Press. https://doi.org/10.1016/B978-0-12-800879-
00054-8
Diaz, G. J., Vargas, M. L., & Cortés, A. (2016). Evaluation of the supplementation
of a feed additive as a potential protector against the
adverse effects of 2.5 ppm T-2 toxin on growing broiler chickens.
Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 68, 709-715.
https://doi.org/10.1590/1678-4162-8416
EFSA. (2012). Scientific Opinion on the welfare of cattle kept for beef
production and the welfare in intensive calf farming systems. EFSA
Journal, 10(5), 2669. https://doi.org/10.2903/j.efsa.2012.2669
EL-Deep, M. H. (2016). POSSIBLE PROTECTIVE EFFECTS OF GLUTATHIONE
IN PREVENTING AFLATOXICOSIS IN EGYPTIAN
LAYING HENS. Egyptian Poultry Science Journal, 36(2), 543-560.
https://doi.org/10.21608/epsj.2016.168796
Guo, H., Wan, H., Lou, W., Khan, R. U., You, J., Huang, B., Hao, S.,
Li, G., & Dai, S. (2024). Deoxynivalenol and T-2 toxin cause liver
damage and egg quality degradation through endoplasmic reticulum
stress in summer laying hens. International Journal of Biometeorology.
https://doi.org/10.1007/s00484-024-02674-w
Guo, L., Zhao, B., Jia, Y., He, F., & Chen, W. (2022). Mitigation Strategies
of Air Pollutants for Mechanical Ventilated Livestock and Poultry
Housing—A Review. Atmosphere, 13(3), Article 3. https://doi.
org/10.3390/atmos13030452
Haque, M. A., Wang, Y., Shen, Z., Li, X., Saleemi, M. K., & He, C. (2020).
Mycotoxin contamination and control strategy in human, domestic
animal and poultry: A review. Microbial Pathogenesis, 142, 104095.
https://doi.org/10.1016/j.micpath.2020.104095
Hoehler, D., & Marquardt, R. R. (1996). Influence of Vitamins E and C on
the Toxic Effects of Ochratoxin A and T-2 Toxin in Chicks. Poultry
Science, 75(12), 1508-1515. https://doi.org/10.3382/ps.0751508
Jones, M. P., & Orosz, S. E. (1996). Overview of avian neurology and
neurological diseases. Seminars in Avian and Exotic Pet Medicine,
(3), 150-164. https://doi.org/10.1016/S1055-937X(96)80004-1
Kępińska-Pacelik, J., & Biel, W. (2021). Mycotoxins—Prevention, Detection,
Impact on Animal Health. Processes, 9(11), Article 11. https://
doi.org/10.3390/pr9112035
Kulcsár, S., Kövesi, B., Balogh, K., Zándoki, E., Ancsin, Z., Erdélyi, M.,
& Mézes, M. (2023). The Co-Occurrence of T-2 Toxin, Deoxynivalenol,
and Fumonisin B1 Activated the Glutathione Redox System
in the EU-Limiting Doses in Laying Hens. Toxins, 15(5), Article 5.
https://doi.org/10.3390/toxins15050305
Lee, J., Cho, H., Song, D., Chang, S., An, J., Nam, J., Lee, B., Kim, S.,
Kim, W. K., & Cho, J. (2023). Effects of Combinations of Toxin
Binders with or without Natural Components on Broiler Breeders
Exposed to Ochratoxin A. Animals, 13(14), Article 14. https://doi.
org/10.3390/ani13142266
Mavrommatis, A., Giamouri, E., Tavrizelou, S., Zacharioudaki, M.,
Danezis, G., Simitzis, P. E., Zoidis, E., Tsiplakou, E., Pappas, A. C.,
Georgiou, C. A., & Feggeros, K. (2021). Impact of Mycotoxins on
Animals’ Oxidative Status. Antioxidants, 10(2), Article 2. https://doi.
org/10.3390/antiox10020214
Meerpoel, C., Vidal, A., Tangni, E. K., Huybrechts, B., Couck, L., De
Rycke, R., De Bels, L., De Saeger, S., Van den Broeck, W., Devreese,
M., & Croubels, S. (2020). A Study of Carry-Over and Histopathological
Effects after Chronic Dietary Intake of Citrinin in Pigs, Broiler
Chickens and Laying Hens. Toxins, 12(11), Article 11. https://doi.
org/10.3390/toxins12110719
Meneely, J., Greer, B., Kolawole, O., & Elliott, C. (2023). T-2 and HT-2
Toxins: Toxicity, Occurrence and Analysis: A Review. Toxins, 15(8),
Article 8. https://doi.org/10.3390/toxins15080481
Puvača, N., Kostadinović, Lj., Popović, S., Lević, J., Ljubojević, D., Tufarelli,
V., Jovanović, R., Tasić, T., Ikonić, P., & Lukač, D. (2016).
Proximate composition, cholesterol concentration and lipid oxidation
of meat from chickens fed dietary spice addition (Allium sativum,
Piper nigrum, Capsicum annuum). Animal Production Science,
(11), 1920-1927. https://doi.org/10.1071/AN15115
Puvača, N., & Ljubojević Pelić, D. (2024). Problems and Mitigation
Strategies of Trichothecenes Mycotoxins in Laying Hens Production.
Journal of Agronomy, Technology and Engineering Management,
(2), 1074-1087. https://doi.org/10.55817/ISAD5453
Puvača, N., Ljubojević Pelić, D., & Tufarelli, V. (2023). Mycotoxins
Adsorbents in Food Animal Production. Journal of Agronomy, Technology
and Engineering Management, 6(5), 944-952. https://doi.
org/10.55817/GYIC7602
Puvača, N., & Vapa, B. (2024). Implementation of food safety policy in the European Union: Guidance, variety, and resolution of challenges.
Pravo - Teorija i Praksa, 41(1), 18-34. https://doi.org/10.5937/
ptp2401018P
Rezar, V., Frankič, T., Narat, M., Levart, A., & Salobir, J. (2007). Dose-Dependent
Effects of T-2 Toxin on Performance, Lipid Peroxidation, and
Genotoxicity in Broiler Chickens. Poultry Science, 86(6), 1155-1160.
https://doi.org/10.1093/ps/86.6.1155
Wielogórska, E., MacDonald, S., & Elliott, C. t. (2016). A review of the
efficacy of mycotoxin detoxifying agents used in feed in light of
changing global environment and legislation. World Mycotoxin Journal,
(3), 419-433. https://doi.org/10.3920/WMJ2015.1919
Yuan, T., Li, J., Wang, Y., Li, M., Yang, A., Ren, C., Qi, D., & Zhang,
N. (2022). Effects of Zearalenone on Production Performance, Egg
Quality, Ovarian Function and Gut Microbiota of Laying Hens. Toxins,
(10), Article 10. https://doi.org/10.3390/toxins14100653
Zhao, L., Feng, Y., Wei, J.-T., Zhu, M.-X., Zhang, L., Zhang, J.-C., Karrow,
N. A., Han, Y.-M., Wu, Y.-Y., Guo, Y.-M., & Sun, L.-H. (2021).
Mitigation Effects of Bentonite and Yeast Cell Wall Binders on AFB1,
DON, and OTA Induced Changes in Laying Hen Performance, Egg
Quality, and Health. Toxins, 13(2), Article 2. https://doi.org/10.3390/
toxins13020156
Zhu, Y., Hassan, Y. I., Watts, C., & Zhou, T. (2016). Innovative technologies
for the mitigation of mycotoxins in animal feed and ingredients—
A review of recent patents. Animal Feed Science and Technology,
, 19-29. https://doi.org/10.1016/j.anifeedsci.2016.03.030
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