Acute phase response in experimentally infected broilers with avian infectious bronchitis virus serotype 4/91


S. SEIFI
S. H. ALIAN SAMAKKHAH
K. ABSALAN FARD
Résumé

Measurement of acute phase proteins is important for diagnosis of animal diseases. In the present study, effects of avian infectious bronchitis virus infection on acute phase response and acute phase proteins were determined. Thirty one-day-old commercial broiler chicks were reared in experimental facilities and, at the age of 21 days, were challenged intranasally with 0.2 mL of allantoic fluid virus suspension (titre 106.5 EID50 per 0.1 mL). Serum samples were obtained prior to challenge and on days 1, 2, and 5 post-inoculation. Haptoglobin, serum amyloid A and C- reactive protein concentrations were measured. Our results showed that all investigated acute phase proteins increased significantly after infection, with mean maximum concentrations between 24 h and 48 h. No correlation was observed between plasma acute phase proteins in the chickens prior and post inoculation of the virus. Haptoglobin was most sensitive factor to change in the exposed birds.

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Références
Asasi K, Mohammadi A, Boroomand Z, Hosseinian SA, Nazifi S (2013) Changes of several acute phase factors in broiler chickens in response to infectious bronchitis virus infection. Poult Sci 92:1989-1996.
Baumann H, Gauldie J (1994) The acute phase response. Immunol Today 15:74-80.
Canova CR, Courtin C, Reinhart WH (1999) C-reactive protein (CRP) in cerebro-vascular events. Atherosclerosis 147:49-53.
Cavanagh D (2007) Coronavirus avian infectious bronchitis virus. Vet Res 38:281–297.
Ceron JJ, Eckersall PD, Martynez-Subiela S (2005) Acute phase proteins in dogs and cats: current knowledge and future perspectives. Vet Clin Pathol 34:85-99.
Chamanza R, Tuossaint MJ, van Ederen AM, van Veen L, Hulskamp-Koch C, Fabri TH (1999) Serum amyloid A and transferring in chicken. A preliminary investigation of using acute-phase variables to assess diseases in chickens. Vet Q 21:158-162.
Cray C, Zaias J, Altman NH (2009) Acute phase response in animals: a review. Comp Med 59:517-526.
Conner JG, Eckersall PD, Ferguson J, Douglas TA (1988) The acute phase response in the dog following surgical trauma. Res Vet Sci 45:107-110.
De Wit JJ (2000) Detection of infectious bronchitis virus. Avian Pathol 29:71–93.
Eckersall PD, Saini PK, Mccomb C (1996) The acute-phase response of acid-soluble glycoprotein, alpha(1)-Acid glycoprotein, ceruloplasmin, haptoglobin and c-reactive protein, in the pig. Vet Immunol Immunopathol 51:377-385.
Feldman BV, Zinkl JG, Jain NC (2000) Schalm’s Veterinary Hematology, 5th edn, Williams & Wilkins, Philadelphia, 1152pp.
Holt PS, Gast RK (2002) Comparison of the effects of infection with Salmonella enteritidis, in combination with an induced molt, on serum levels of the acute phase protein α1-acid glycoprotein, in hens. Poult Sci 81:1295-1300.
Inoue M, Satoh W, Murakami H (1997) Plasma α1-acid glycoprotein in chickens infected with infectious bursal disease virus. Avian Dis 41:164-170.
Jackwood MW (2012) Review of infectious bronchitis virus around the world. Avian Dis 56:634-641.
Jiang Z, Schatzmayr G, Mohnl M, Applegate TJ (2010) Net effect of an acute phase response–Partial alleviation with probiotic supplementation. Poult Sci 89:28-33.
Mosleh N, Nazifi S, Nili H, Habibi H (2013) Effect of H9N2 virus infection on the acute phase response in Chukar Partridges (Alectoris Chukar). Bulgarian J Vet Med 16:20-28.
Nazifi S, Dadras H, Hoseinian SA, Ansari-Lari M, Masoudian M (2010) Measuring acute phase proteins (haptoglobin, ceruloplasmin, serum amyloid A, and fibrinogen) in healthy and infectious bursal disease virus-infected chicks. Comp Clin Pathol 19:283-286.
Nazifi S, Tabande MR, Hosseinian SA, Ansari-Lari M, Safari H (2011) Evaluation of sialic acid and acute-phase proteins (haptoglobin and serum amyloids A) in healthy and avian infection bronchitis virus virus-infected chicks. Comp Clin Pathol 20:69-73.
Nielsen OL, Jensenius JC, Jorgensen PH, Laursen SB (1999) Serum level of chicken mannan-binding lectin (MBL) during virus infections, indication that chicken MBL is an acute phase reactant. Vet Immunol Immunopathol 70:309-316.
Reed LJ, Muench H (1938): A simple method of estimating fifty per cent endpoints. Am J Epidemiol 27:493-497.
Saini PK, Webert DW (1991) Application of acute phase reactants during antemortem and postmortem meat inspection. J Am Vet Med Assoc 198:1898-1902.
Seifi S, Asasi K, Mohammadi A (2010) Natural co-infection caused by avian influenza H9 subtype and infectious bronchitis viruses in broiler chicken farms. Vet Arhiv 80:269–281.
Tohjo H, Miyoshi F, Uchida E, Niyama M, Syuto B, Moritsu Y, Ichikawa S, Takeuchi M. (1995) Polyacrylamide gel electrophoretic patterns of chicken serum in acute inflammation induced by intramuscular injection of turpentine. Poult Sci 74:648655.
Xie H, Huff GR, Balog JM, Holt P, Rath NC (2002) Identification of ovotransferrin as an acute phase protein in chickens. Poult Sci 81:112-120.
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