The effect of Vitamin C in the therapy of haemolactia in dairy cows


M Ninković
https://orcid.org/0000-0003-0173-7795
S Arsić
J Žutić
J Bojkovski
https://orcid.org/0000-0001-7097-2559
N Zdravković
N Panousis
https://orcid.org/0000-0002-7584-8191
Abstract

The aim of this study was to evaluate the effects of intravenous administration of vitamin C in the therapy of haemolactia in dairy cows. Haemolactia is often of unknown origin, and it can occur due to vitamin C deficiency. The research was carried out on twenty-eight dairy cows having clinical signs of haemolactia, with a clinical score of 2 or 3. The cows of the group A (n=10) were treated intravenously with 2000 mg vitamin C, those of the Group B (n=10) with 3000 mg vitamin C intravenously, whereas cows of group C (n=8) were served as controls and remained untreated. The vitamin C application was once per day intravenously until symptoms disappeared. The appearance of milk and the therapeutic effects of vitamin C were monitored during milking, based on the visual appearance of milk. The average duration of haemolactia in both treated groups A and B was significantly lower (72 h and 68 h, respectively) compared to the control group C (102 h) (p<0.05 for both). Vitamin C was shown to be beneficial in the therapy of haemolactia; no statistical difference was observed regarding the administered doses of vitamin C (2000 vs. 3000 mg). The results prove the importance of vitamin C administration to shorten the duration of haemolactia in dairy cows

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Biografia autore
M Ninković, Scientific Institute of Veterinary Medicine of Belgrade

Department of Healthcare, Institute of Veterinary Medicine of Belgrade

Riferimenti bibliografici
Ayaz MM (1999) Haematogalactia in goats and buffalo. Pak. Vet. J.19
(3), 161-162.
Bani Ismail Z (2016) Successful treatment of bloody milk not associated
with physiologic udder edema in lactating Holstein dairy cows using
intravenous formalin administration. Bull. UASVM Vet. Med., 73,
(1), 153-160.
Bani Ismail Z, Abutarbush SM, Al-Qudah K, Omoush F (2020) Serum
and milk concentrations of oxidant and anti-oxidant markers in dairy
cows affected with bloody milk. Polish Journal of Vet Sci, 23(3).
Chaiyotwittayakun A, Erskine R J, Bartlett PC, Herdt TH, Sears PM, Harmon R J (2002) The effect of ascorbic acid and L-histidine therapy
on acute mammary inflammation in dairy cattle. J Dairy Sci, 85(1),
-67.
Fraile L, Arcas A, Jiménez LM, Mallo J Armengol R (2019) Treatment
with etamsylate reduces haemolactia in lactating dairy cows. J. Dairy
Res, 86, 193-195.
George LW, Divers TJ, Ducharme N, & Welcome FL (2008) Diseases of
the teats and udder. In: Rebhun’s Diseases of Dairy Cattle. 2nd Ed.
Divers, T.J., and S.F. Peek (eds.). Saunders-Elsevier Publishers, St.
Louis, USA. p: 335
Hazra A, Gogtay N (2017) Biostatistics Series Module 9: Survival Analysis. Indian J Dermatol, 62(3):251-257.
Hungerford TG Hungerford’s Diseases of Livestock. McGraw-Hill Book
Co., Sydney,1990.
Kwon JH, Kim D, Cho H, Shin BS (2019) Ascorbic acid improves thrombotic function of platelets during living donor liver transplantation
by modulating the function of the E3 ubiquitin ligases c-Cbl and
Cbl-b. J. Int Med Res., 47(5), 1856-1867.
Mohammed BM, Sanford KW, Fisher BJ, Martin J, Contaifer D, Jr, Warncke UO, Wijesinghe D. S, Chalfant CE, Brophy DF, Fowler
IAA, Natarajan R (2017) Impact of high dose vitamin C on platelet
function. World J crit Care Med, 6(1), 37-47.
Mohammed BM, Fisher BJ, Kraskauskas D, Ward S, Wayne JS, Brophy DF, Fowler AA3rd, Yager DR, Natarajan R (2016) Vitamin C
promotes wound healing through novel pleiotropic mechanisms. Int
Wound J., 13(4), 572-584.
Muhammad G, Rashid I (2015) Causes, diagnosis and treatment of blood
in milk (haemolactia) in cows and buffaloes. Adv. Anim.Vet. Res.,
(1), 1-6.
Ranjan R, Ranjan A, Dhaliwal GS, & Patra RC (2012) L-Ascorbic acid (vitamin
C) supplementation to optimize health and reproduction in cattle, Vet Q,
:3-4, 145-150.
Radostitis OM, Gay CC, Hinchcliff KW, Constable PD (2007) Diseases
of the mammary glands. In: Veterinary Medicine. 10th ed, Saunders
Elsevier, Philadelphia, Pennsylvania, 673-76.
Sathler PC, Lourenço AL, Saito MS, Arêas AP, Rodrigues CR, Cabral
LM, Catro HC, & Kang, H. C. (2016) The antihemostatic profile of
vitamin C: Mechanisms that underlie the technical application of a
physiological molecule. Arch Biol Sci., 68(2), 325-331
Yang FL, Li XS (2015) Role of antioxidant vitamins and trace elements in
mastitis in dairy cows. J. Adv. Vet. Anim Res., 2(1), 1-9
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