Evaluation of the best vaccination regimen against Gumboro disease, based on the histopathologic lesions of bursa of Fabricius, in broilers


Published: Jan 31, 2018
Keywords:
Gumboro disease vaccination regimen bursa of Fabricius broilers chickens.
B. BOUYIOUKLIS (Π. ΜΠΟΥΓΙΟΥΚΛΗΣ)
S. LEKKAS (Σ. ΛΕΚΚΑΣ)
I. GEORGOPOULOU (Ι. ΓΕΩΡΓΟΠΟΥΛΟΥ)
P. IORDANIDIS (Π. ΙΟΡΔΑΝΙΔΗΣ)
Abstract

For the evaluation of the best vaccination regimen against Gumboro disease using the vaccine strain D-78, based on the histopathologic lesions of bursa of Fabricius, 5 groups of experimental animals (A, B, C, D, E) of 15 chicks each were used. The chicks of group Β received the D-78 vaccine strain with the drinking water at the age of 14 days, those of C at the age of 8 and 11 days, and those of D at the age of 8 and 16 days, while the chicks of the other groups (A and E) remained unvaccinated. In the following, the chicks of the A, B, C and D groups were infected with a field strain of Gumboro disease virus, while those of E remained unvaccinated and uninfected as a control group. After 10 days, all chicks were killed and their bursae examined histological. It was established that the histopathologic lesions to the bursae of group C chicks were of a slighter degree than those of all the other challenged groups and therefore the protection to bursa of Fabricius against the disease is better with this vaccination regimen.

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References
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