Evaluation of the best vaccination regimen against Gumboro disease, based on the histopathologic lesions of bursa of Fabricius, in broilers


Опубликован: Jan 31, 2018
B. BOUYIOUKLIS (Π. ΜΠΟΥΓΙΟΥΚΛΗΣ)
S. LEKKAS (Σ. ΛΕΚΚΑΣ)
I. GEORGOPOULOU (Ι. ΓΕΩΡΓΟΠΟΥΛΟΥ)
P. IORDANIDIS (Π. ΙΟΡΔΑΝΙΔΗΣ)
Аннотация

For the evaluation of the best vaccination regimen against Gumboro disease using the vaccine strain D-78, based on the histopathologic lesions of bursa of Fabricius, 5 groups of experimental animals (A, B, C, D, E) of 15 chicks each were used. The chicks of group Β received the D-78 vaccine strain with the drinking water at the age of 14 days, those of C at the age of 8 and 11 days, and those of D at the age of 8 and 16 days, while the chicks of the other groups (A and E) remained unvaccinated. In the following, the chicks of the A, B, C and D groups were infected with a field strain of Gumboro disease virus, while those of E remained unvaccinated and uninfected as a control group. After 10 days, all chicks were killed and their bursae examined histological. It was established that the histopathologic lesions to the bursae of group C chicks were of a slighter degree than those of all the other challenged groups and therefore the protection to bursa of Fabricius against the disease is better with this vaccination regimen.

Article Details
  • Раздел
  • Research Articles
Скачивания
Данные скачивания пока недоступны.
Библиографические ссылки
Αρτοποιός Ε. Η νόσος του Gumboro. Ελλ. Κτην. 1978,20:53-67.
Kaufer Ι and Weiss Ε. Significance of bursa of Fabricius as target organ in infectious bursal disease of chickens. Infection and Immmunity 1980,27:364-367.
Helmboldt CF and E Garner. Experimentally indused Gumboro disease (IBA). Avian Pis 1964,8:561-575.
Hirai Κ and BW Calnek. In vitro replication of infectious bursal disease virus in established lymphoid cell lines and chicken Β lymphocytes. Infect Immunol 1979,25:964-970.
Ley DH, R Yamamoto and AA Bickford. The pathogenesis of infectious bursal disease: serologic, histopathologic and clinical chemical observations. Avian Pis 1983,27:1060-1085.
Müller Η. Replication of infectious disease virus in lymphoid cells. Arch Virol 1986,87:191-203.
Nakai Τ and Κ Hirai. In vitro infection of fractionated chickenlymphocytes by infectious bursal disease virus. Avian Pis 1981,25:831-838.
Giamborne JJ, JP Ponahoe, PL Pawe and CS Edison. Specific suppression of the bursa dependent immune system of chicks with infectious bursal disease virus. Am J Vet Res 1977, 38:581-583.
Hirai Κ, Κ Kunihiro and S Shimakura. Characterization of immunosuppression in chickens by infectious bursal disease virus. Avian Pis 1979,23:950-965
Allan WH, JT Faragher, and GA Cullen. Immunosupression by the infectious bursal agent in chickens immunized against Newcastle disease. Vet Ree 1972,90:511-512.
Anderson WI, WM Reid, PP Lukert and OJ Fletcher. Influence of infectious bursal disease on the development of immunity to Eimeria tenella. Avian Pis 1977,21:637-641.
Pejkovski C, FC Pavelaar and Β Kouwenhoven. Immunosupressive effect of infectious bursal disease virus on vaccination against infectious bronchitis. Avian Pathol 1979, 8:95-106.
Cheville NF. Studies on the pathogenesis of Gumboro disease in the bursa of Fabricius, spleen and thymus of the chicken. Am J Pathol 1967,51:527-551.
Graig W, RN Brewer and SA Edgar. Studies on infectious bursal disease in chickens. 2. Scoring microscopic lesions in the bursa of fabricius, thymus, spleen and kidney in gnotobiotic and battery reared White Leghorns experimentally infected with infectious bursal disease virus. Poultry Sci 1980,59:1006-1017.
Peters G. Histology of Gumboro disease. Beri. Muench Tierztl Wochenschr 1967,80:394-396.
Rossales AG, Ρ Villegas, PP Lukert, OJ Fletcher, MA Mohamed and J Brown. Isolation, Intentification, and Pathogenicity of Two Field Strains of Infectious Bursal Pisease Virus. Avian Pis 1989,33:35-41.
Λέκκας Σ. Εργαστηριακές Τεχνικές Ιστοπαθολογίας. Θεσσαλονίκη 1979.
Kouwenhoven Β and J van den Bos. Control of very virulent infectious bursal disease virus (Gumboro) in the Netherlands with more virulent vaccines. International Poultry Symposium 1995:29-32.
Vanmarcke J. The control of very virulent infectious bursal disease in developing countries. International Poultry Symposium 1995:109-110.
Μπουγιουκλής ΑΠ. "Συμβολή στη μελέτη της ανοσοπροφύλαξης των κρεοπαραγωγών ορνιθιων από τη νόσο του Gumboro". Διδακτορική διατριβή, Θεσσαλονίκη 1999.
Naqi SA, Β Marquez and Ν Sahin. Maternal antibody and its effect on infectious bursal disease immunization. Avian Pis 1983,27:623-631.
Vindevogel H. Manuel de pathologie aviaire 1992:155-163.
Cullen BR, Lomedico PT and Ju. G. Transcriptional interference in avian retroviruses-implications for the promoter insertion model of leukaemogenesis. Nature (London) 1984, 307: 241.
Наиболее читаемые статьи этого автора (авторов)