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A case of canine epitheliotropic lymphoma (mycosis fungoides)

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M. N. SARIDOMICHELAKIS (Μ. Ν. ΣΑΡΙΔΟΜΙΧΕΛΑΚΗΣ), C. K. KOUTINAS (X.K. ΚΟΥΤΙΝΑΣ), A. F. KOUTINAS (Α. Φ. ΚΟΥΤΙΝΑΣ)
M. N. SARIDOMICHELAKIS (Μ. Ν. ΣΑΡΙΔΟΜΙΧΕΛΑΚΗΣ), C. K. KOUTINAS (X.K. ΚΟΥΤΙΝΑΣ), A. F. KOUTINAS (Α. Φ. ΚΟΥΤΙΝΑΣ)

Abstract


The clinical picture, diagnosis and treatment of a dog with epitheliotropic lymphoma are presented. The dog (male, mongrel, 13-year old) was admitted to our Clinic with a 5-month history of non-pruritic skin lesions. At clinical examination a multifocal to diffuse exfoliative erythrodermia was the most striking finding. Diagnosis of epitheliotropic lymphoma was based on cutaneous histopathology, revealing a dense dermal and epidermal lymphocytic infiltration and Pautrie microabcess formation. Initial treatment with isotretinoin had a poor impact on skin lesions that progressed to the macular stage. On the contrary, combination chemotherapy with Lasparaginase and isotretinoin resulted in substantial improvement. The animal died, following a short period of depression and inappetance, 15 months after the first appearance of skin lesions and 10 months after diagnosis.


Keywords


επιθηλιοτρόπο λέμφωμα; L-ασπαραγινάση; ισοτρετινοΐνη; σκύλος

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References


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