Practical bone marrow cytology in the dog and cat
In companion animal medicine, bone marrow (BM) aspiration cytology is a cost-effective diagnostic tool, which provides excellent morphological detail of cells and infectious agents. The major indications for BM aspiration include unexplained clinical manifestations (e.g., fever, body weight loss), persistent hematological or biochemical abnormalities (e.g., anemia, leukocytosis), diagnosis and/or staging of malignancies (e.g., lymphoma, mast-cell tumor), diagnosis of important infectious diseases such as leishmaniosis (Leishmania infantum) and canine monocytic ehrlichiosis (Ehrlichia canis) and evaluation of canine iron stores. Complications associated with BM aspiration are rare and the equipment and supplies required minimal, hence accounting for the popularity of this procedure in the clinical setting compared to BM core biopsy. This review focuses on the technical details pertaining to the collection of BM aspirate material, including the usual anatomic sites for sampling, the equipment required, the preparation of the animal, the aspiration technique and the BM material processing for good quality slide preparation. The description of the cellular population normally anticipated in the BM of the dog and cat and the systematic approach in evaluating and interpreting the BM cytological findings are also highlighted. In the last part of this review, the current classification guidelines for the canine and feline BM malignancies are briefly outlined.
- How to Cite
MYLONAKIS (Μ.Ε. ΜΥΛΩΝΑΚΗΣ) M. E., & HATZIS (Α. ΧΑΤΖΗΣ) A. (2017). Practical bone marrow cytology in the dog and cat. Journal of the Hellenic Veterinary Medical Society, 65(3), 181–196. https://doi.org/10.12681/jhvms.15534
- Vol. 65 No. 3 (2014)
- Review Articles
Authors who publish with this journal agree to the following terms:
· Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution Non-Commercial License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
· Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g. post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
· Authors are permitted and encouraged to post their work online (preferably in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.