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Exploration the Quality of Life and the related factors in women with recent diagnosis of gynecological cancer, before the surgical treatment, in Greece

Published: Δεκ 21, 2020
Quality of life gynecological cancer pretreatment recent diagnosis
Georgia Fasoi
Maria Bourazani
Dimitris Papatheodorou
Eugenia Vlachou
Georgia Toylia
Evridiki Kaba
Panagiota Lalou
Christina Sotnikova
Martha Kelesi

Introduction: In Greece, it is estimated that annually 600 new cases of cervical cancer are diagnosed, being the third most common form of cancer in women after breast cancer (22.9%) and colon cancer (9.4%).In addition to being life-threatening, such a diagnosis can also represent the psychological impact of gynecological cancers; there are negative emotional consequences of such a diagnosis for both patients and their families affecting the quality of life (QOL) of patients with gynecological cancer.

Aim: To examine the quality of life (QOL) of women with recent diagnosis of gynecologic cancer (RDGC) in Greece during their illness and to identify the psychosocial problems and the symptoms faced by women in the early stages of the disease.

Material and Method: A prospective study of 63 patients with RDGC before undergoing hysterectomy, who completed the EORTC QLQ-C30 questionnaire.

Results: The patients were between 45 and 50 years old (19.6%). Impaired physical functioning of women with RDGC was associated with strenuous activity or a long walk. Emotionally, patients showed a lack of concentration, tension, anxiety, irritation and depression. Age was negatively correlated with depression (p-value = 0.05<0.1). More than half of women had pain and few of them suffered a lot. Pain, shortness of breath (dyspnea) and fatigue caused discomfort and interference with daily living activities. More than half had sleeping disorders. Constipation and lack of appetite were common symptoms of the digestive system. Most women had no social or financial problems and rated their quality of life “very good”.

Conclusions: Women with a RDGC, besides the common physical symptoms such as fatigue, pain, anorexia, sleep disorders and loss of appetite, had also emotional disorders. The feeling of depression was present in most patients. It was found that the younger the patient, the more depressed they feel.

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Antsaklis A. Obstetrics and Gynecology. Parisianos Publica-tions, Athens, 2011;1:150-159.
Goker A, Guvenal T, Yanikkerem E, Turhan A, Koyuncu FM. Quality of Life in Women with Gynecologic Cancer in Turkey. Asian Pac J Cancer Prev, 2011;12(11):3121-3128. {}
Fotiou S. Gynecological Oncology. Paschalidis Editions, Athens, 2009;1:166-168.
Pınar G, Algier L, Çolak M, Ayhan A. Quality of life in patients with gynecologic cancer. Int J Hematol Oncol, 2008;3(18):141-149. {}
Özaras G, Özyurda F. Quality of life and Influencing factors in patients with gynecologic cancer diagnosis at Gazi University, Turkey. Asian Pac J Cancer Prev, 2010;1(5):1403-1408. {}
Lerman R, Jarski R, Rea H, Gellish R, Vicini F. Improving symp-toms and quality of life female cancer survivors: a randomized controlled study. Ann Surg Oncol, 2011;19(2):373-378. doi:10.1245/s10434-011-2051-2
Yaman S, Ayaz S. Psychological Problems Experienced by Women with Gynecological Cancer and How They Cope with It: A Phenomenological Study in Turkey. Health Soc Work, 2016;41(3):173-181. doi:10.1093/hsw/hlw030
Al Zahrani AM, Alalawi Y, Yagoub U, Saud N, Siddig K. Quality of life of women with breast cancer undergoing treatment and follow-up at King Salman Armed Forces Hospital in Tabuk. Breast Cancer (Dove Med Press), 2019;11:199-208. doi:10.2147/BCTT.S200605
Kontodimopoulos N, Ntinoulis K, Niakas D. Validity of the Greek EORTC QLQ-C30 and QLQ-BR23 for measuring health-related quality of life in breast cancer patients. Eur J Cancer Care, 2011;20(3): 354-361. doi:10.1111/j.1365-2354.2009.01170.x.
ESMO – European Society for Medical Oncology, 2012. Availa-ble on line: {}, Accessed at: 27/11/2019.
Balasubramaniam K, Ravn P, Depont Christensen R, Sønder-gaard J, Ejg Jarbøl D. Predictive values of gynaecological cancer alarm symptoms in a general population. Eur J Gynaecol Oncol, 2018;39: 543-547. {}
Martignetti J. Gynecologic Cancer Screening Tool Could Lower Incidence Mortality. Oncology Times, 2019;41(3):9-14. doi:10.1097/01.COT.0000553533.53758.1a
Costas L, Frias-Gomez J, Guardiola M, et al. New perspectives on screening and early detection of endometrial cancer. Int J Can-cer, 2019;145(12):3194-3206. {}
Farrokhzadi L, Dhillon HM, Goumas C, Young JM, Cust AE. Physical Activity Correlates, Barriers and Preferences for Women with Gynecological Cancer. Int J Gynecol Cancer, 2016;26:1530-1537. doi:10.1097/IGC.0000000000000790
Wada S, Shimizu K, Inoguchi H, et al. The Association Between Depressive Symptoms and Age in Cancer Patients: A Multicen-ter Cross-Sectional Study. J Pain Symptom Manage, 2015;50(6):768-777. {}
Yusof S, Nadzirah F, Hashim NK, Dasima R. Depressive Symp-toms among Cancer Patients Undergoing Chemotherapy. Pro-cedia Soc Behav Sci, 2016;234:185-192. doi:10.1016/j.sbspro.2016.10.233
Park ME, Rosenstein DL. Depression in adolescents and young adults with cancer. Dialogues Clin Neurosci, 2015;17(2):171-180. {}
Mystakidou K, Tsilika E, Parpa E, Katsouda E, Galanos A, Vlahos L. Assessment of anxiety and depression in advanced cancer patients and their relationship with quality of life. Qual Life Res. 2005;14(8):1825-1833. doi:10.1007/s11136-005-4324-3.
Gagliese L, Gauthier LR, Rodin G. Cancer pain and depression: A systematic review of age-related patterns. Pain Res Manag, 2007;12(3): 205-211. doi:10.1155/2007/150126
Nowe E, Friedrich M, Leuteritz K, et al. Cancer-Related Fatigue and Associated Factors in Young Adult Cancer Patients, J Ado-lesc Young Adult Oncol, 2019;8(3): 297-303. doi:10.1089/jayao.2018.0091
Wang XS, Woodruff HF. Cancer-related and treatment-related fatigue. Gynecol Oncol, 2015;136(3):446-452. doi:10.1016/j.ygyno.2014.10.013
Laird B, Scott A, Colvin L, et al. Pain, Depression, and Fatigue as a Symptom Cluster in Advanced Cancer. J Pain Symptom Man-age, 2011;42(1):1-11. {}
Stark L, Tofthagen C, Visovsky C, McMillan SC. The Symptom Experience of Patients with Cancer. J Hosp Palliat Nurs, 2013;14(1):61-70. doi:10.1097/NJH.0b013e318236de5c.
Ader R. Psychoneuroimmunology. Elsevier Academic Press, 4th Edition, 2007; 2: 606-0.
Ruel S, Ivers H, Savard MH, et al. Insomnia, immunity and infec-tions in cancer patients: Results from a longitudinal study. Health Psychol, 2020;39(5):358-369. doi:10.1037/hea0000811
Whicker M, Black J, Altwerger G, et al. Management of sexuali-ty, intimacy, and menopause symptoms in patients with ovarian cancer. Am J Obstet Gynecol, 2017;217(4): 395-403. doi:10.1016/j.ajog.2017.04.012
Funston G, O’Flynn H, Ryan NAJ, Hamilton W, Crosbie EJ. Rec-ognizing Gynecological Cancer in Primary Care: Risk Factors, Red Flags and Referrals. Adv Ther, 2018;35(4):557-589. doi:10.1007/s12325-018-0683-3
Liang M, Pisu M, Summerlin S, et al. Extensive financial hard-ship among gynecologic cancer patients starting a new line of therapy. Gynecol Oncol, 2020;156(2): 271-277. {}
Manne S, Kashy DA, Virtue S, et al. Acceptance, social support, benefit-finding, and depression in women with gynecological cancer. Quality of Life Research, 2018;27(11): 2991-3002. doi:10.1007/s11136-018-1953-x
Niedzweiedz CL, Knifton L, Robb K, Katikireddi SV, Smith DJ. Depression and anxiety among people living with and beyond cancer: a growing clinical and research priority. BMC Cancer, 2019;19:943-950. {}
Izycki D, Wozniak K, Izycka N. Consequences of gynecological cancer in patients and their partners from the sexual and psy-chological perspective. Prz Menopauzalny, 2016;15(2):112-116. doi:10.5114/pm.2016.61194
Pitman A, Suleman S, Hyde N, Hodgkiss A. Depression and anx-iety in patients with cancer. BMJ 2018;25:361:k1415. doi:10.1136/bmj.k1415.
Manne S, Myers-Virtue S, Kasgy D, et al. Resilience, positive coping, and quality of life among women newly diagnosed with gynecological cancers. Cancer Nurs, 2016;38(5):375-382. doi:10.1097/NCC.0000000000000215
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