Study upon the efficacy of apramycin in the treatment of colibacillosis in young calves


Apramycin, a new aminocy clitol antibiotic produced by a strain o f S t r e p t o m y c e s te n e b r a r i u s has been evaluated as a treatment of naturally occuring colibacillosis in young calves. Results are reported from 3 field trials, involving 95 animals, in Greece. In 2 of those trials, apramycin was administered orally at a dose rate of 20 and 40 mg/kg bodyweight and at 20 mg/kg b.w. by injection in the 3rd trial (Table I).

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B0rki, F. (1978). Ίογενή Νοσήματα τών Βοοειδών - Μέτρα Προλήψεως στους Παχυνομένους Μόσχους. Διάλεξις δοθείσα είς τήν Κτηνιατρικήν Σχολή του Α. Π. Θεσ/νικης.
Buxton, Α. and Fraser, G. (1977). Animal Microbiology, 1st Edition, Vol. I. pp 93-102 Oxford: Blackwell Scientific Publications.
Fisher, E. W. and de la Fuente, G. H (1971). Antibiotics and Calf Diarrhoea - the Effect of Serum Immune Globulin Concentations. Veterinary Record 89: 579 - 582
Gorham, P. E., Speer, V.C. and Ose, E.E. (1976). Apramycin, a new aminocyclitol antibiotic: 3. Treatment of colibacillosis in weaned pigs. Proceedings, I.P.V.S. Congress, Iowa, U.S.A.
Me Ewan, A.D., Fisher, E. W., Selman, I. E. and Penhaie, W.J., (1970). A turbidity test for the estimation of immune globulin levels in neonatal calf serum. Clinica Chimica Acta, 27: 155-163.
Ο' Connor, S., Lam, L.K., Jones, N.D. and Chaney, M.O., (1973). Apramycin, a unique aminocyclitol antibiotic. Paper presented at 165th A.C.S. National Meeting, Dallas Texas, U.S.A.
Παπαδόπουλος, Ο., (1972). Νόσοι έξ Έσχεριχών είς τα ζώα. Πρακτικά 5ου Έθνικοΰ Συνεδρίου Μικροβιολογίας, 'Αθήναι.
Pankhurst, J. W. (1976). Trials with a new Gram-negative antibiotic for enteric diseases in calves. Paper presented at the 2nd European Congress /British Vet. Ass.
Pankhurst, J.W., Diaz, M., Zeri, A. and Launay, M. (1975). Treatment of disease in the young calf with apramycin. Proceedings of the XXth World Veterinary Congress, Thessaloniki.
Ryden, R. and Moore, BJ. (1977). In vitro activity of apramycin, a new aminocyclitol antibiotic. Journal of Antimicrobial Chemotherapy, 3: 609-613.
Στοφόρος Ε., Κυριακής Σ., Άνδρεώτης Ι., Τσάλτας Κ., Σίμος Ε. Και Στοϋτσίου Κ., (1978). Μελέτη έπί της δραστηριότητος της δια του ποσίμου ύδατος χορηγούμενης άπραμυκίνης είς άπογαλακτισθέντα χοιρίδια πάσχοντα έκ κολοβακτηριδιάσεως. Δελτίον Ελληνικής Κτηνιατρικής Εταιρείας, Τομ. 29, Τευχ. 2.
Stoforos Ε., Kyriakis S., Antreotis J., Tsaltas C, Donos A. and Papaharisis G., (1978). Apramycin injection for the treatment of neonatal colibacillosis in piglets. Proceedings, 5th World I.P.V.S. Congress, Zagreb, Yugoslavia.
Wick, W.E. and Welles, J. S., (1968). Nebramycin, a new broad spectrum antibiotic complex. IV: In vitro and in vitro labaratory evaluation. Antimicrobial Agents and Chemotherapy - 1967. American Society for Microbiology, Bethesda (1968) pp. 341-8.
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