Nitrate poisoning in ruminants

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Published: Dec 6, 2017
DOI: https://doi.org/10.12681/jhvms.15098
Keywords:
Nitrates poisoning ruminants
P. D. KATSOULOS (Π. Δ. ΚΑΤΣΟΥΛΟΣ)
Scholar of the Greek State Scholarships, Clinic of Productive Animal Medicine, Faculty of Veterinary Medicine, AUT
N. PANOUSIS (Ν. ΠΑΝΟΥΣΗΣ)
Clinic of Productive Animal Medicine, Faculty of Veterinary Medicine, AUT
H. KARATZIAS (Χ. ΚΑΡΑΤΖΙΑΣ)
Clinic of Productive Animal Medicine, Faculty of Veterinary Medicine, AUT
Abstract

This paper describes the nitrate - nitrite poisoning of ruminants. This disease is caused by the ingestion of large amount of nitrate salts, which are reduced in the rumen to nitrite ions. Nitrites, after their absorption, cause the formation of methemoglobin and, in turn, respiratory and circulatory distress. The aim of the treatment is to reduce the percentage of methemoglobin in blood and to stop the continuing production of nitrite ions in the rumen. For the prevention of the disease, avoidance of feedstuff rich in nitrates and improvement of the water quality, are suggested.

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References
Angus KW (2000) Inorganic and organic poisons. In: Diseases of Sheep. 3rd ed, Martin W.B., Aitken I.D. (ed.), Blackwell Science,: 368- 378.
Argyroudis S, Spais AG, Emmanouilidis I (1985) Poisoning in goats by plants of Amaranthus spp., rich in nitrates. Hel Vet, 1: 1-7
Baranova M, Mal'a P, Burdova Ο (1993) Transport of nitrates and nitrites into the milk of dairy cows through the digestive system. Veterinarni Medicina, 38 (10): 581-588 (abstract).
Blum JW, Dosogne H, Vangroenweghe F, Hammon HM, Bruckmaier RM, Burvenich C (2000) Tumor necrosis factor-α and nitrite/nitrate responses during acute mastitis induced by Escherichia coli infection and endotoxin in dairy cows. Dom Anim Endoc, 19: 223-235.
Blum JW, Morel C, Hammon HM, Bruckmaier RM, Jaggy A, Zurbriggen A, Jungi Th (2001) High constitutional nitrate status in young cattle. Comp Bioch Phys Part A, 130: 271-282.
Bouchard L, Biais S, Desrosiers C, Zhao X, Laçasse Ρ (1999) Nitric oxide production during endotoxin-induced mastitis in the cow. J Dairy Sci, 82 (12): 2574-2581.
Brunning-Fann CS, Kaneene JB (1993) The effects of nitrate, nitrite and N-nitroso compounds on animal health. Vet Hum Toxicol, 35(3): 237-253.
Buck WB (1969) Laboratory toxicologic test and their interpretation. J Am Vet Med Assoc, 155 (12): 1928-1941.
Burrows GE, Horn GW, Mc New RW, Croy LI, Keeton RD, Kyle J (1987) The prophylactic effect of corn supplementation on experimental nitrate intoxication in cattle. J Anim Sci, 64 (6):1682-1689.
Cawley GD, Collings DF, Dyson DA (1977) Nitrate poisoning. Vet Ree, 101: 305-306.
Cerjan-Stefanovic S, Kastelan-Macan M, Filipan Τ (1992) Ion Exchange characterisation of Modified Zeolite. Water Sci and Techn, 26: 2269-2272.
Church DC (1975) Nutritional Problems. In: Digestive Physiology and Nutrition of ruminants V.l. 2nd ed, Church D.C (ed.), Ο & Β Books,: 337-339.
Ciambelli Ρ, Corbo Ρ, Lumare F, Porcelli C (1984)Ammonium Ion Exchange with Phillipsite Tuff in Relation to Aquacultural Systems. In: Zeo-Agriculture Use of Natural Zeolites in Agriculture and Aquaculture. Pond W.G., Mumpton FA. (ed.), International Committee on Natural Zeolites Brockport, New York,: 251-258.
Colella C, Aiello R, Nastro A (1984) Evaluation of Phillipsite Tuff for the Removal of Ammonia from Aquacultural Wastewaters. In: Zeo-Agriculture Use of Natural Zeolites in Agriculture and Aquaculture. Pond W.G., Mumpton FA. (ed.), International Committee on Natural Zeolites Brockport, New York,: 245-250.
Dinkla ET (1976) Nitrate poisoning in cattle in the province of Goningen. Report on a number of cases. Tijd Voor Diergen, 101 (19): 1096-1099 (abstract).
Dixit VD, Parvizi Ν (2001) Pregnancy stimulates secretion of adenocorticotropin and nitric oxide from peripheral bovine lymphocytes. Biol Rep, 64 (1): 242-248.
Dixon PM, Brown R (1977) Nitrate and nitrite poisoning. Vet Ree, 101: 392.
Emerick RJ, Embry LB, Seerley RW (1965) Rate of formation and reduction of nitrite-induced methemoglobin in vitro and in vivo as influenced by diet of sheep and age of swine. J Anim Sci, 24:221-230.
Fotis G (1999) Aquatic Environment. In: Fish Raising and Medicine part A. Synchrony Paidia Thessalonica,: 40-48.
Geissler C, Steinhofel O, Ulbrich M (1991) The nitrate content in milk. Archiv Fur Tier, 41 (6): 649-656 (abstract).
Georgiev Ρ, Nikolov I, Simeonov S.P, Iordanova V (1987) Dynamics of thyroid hormones and haematological and biochemical indices in chronic nitrate poisoning in sheep. Vet Med Nauki, 24 (10):58-62.
Hirvonen J, Eklund K, Teppo AM, Huszenica G, Kulcsar M, Saloniemi H, Pyorala S (1999) Acute phase response in dairy cows with experimentally induced Escherichia coli mastitis. Acta Vet Scand, 40 (1): 35-46 (abstract).
Horner RF (1982) Suspected ammonium nitrate fertilizer poisoning in cattle. Vet Ree, 110: 472-474.
Horsch CM, Holway JE (1984) Use of Clinoptilolite in Salmon Rearing. In: Zeo-Agriculture Use of Natural Zeolites in Agriculture and Aquaculture. Pond W.G., Mumpton FA. (ed.), International Committee on Natural Zeolites Brockport, New York,: 235-243.
Jainudeen MR, Hansel W, Davison KL (1965) Nitrate toxicity in dairy heifers. 3. Endocrine responses to nitrate ingestion during pregnancy. J Dairy Sci, 48: 217-221.
Jones GA (1972) Dissimilatory metabolism of nitrate by rumen microbiota. Can J Microbiol, 18 (12):1783-1787.
Jones TO, Jones DR (1977) Nitrate/nitrite of cattle from forage crops. Vet Ree, 101: 266-267.
Kammerer M, Pinault L, Pouliquen H (1992) Content of nitrate in milk. Relationship with its concentration in the water supply for livestock. Annales de Recherches Vétérinaires. Annals of Vet Res, 23 (2): 131-138 (abstract).
Kilikidis S (1997) Biogeochemical circles of inorganic elements. In: Ecology and Environment Protection. Synchrony Paideia Thessaloniki,: 122-126.
Konstantinov AS, Pelipenko MY (1983) Use of Zeolite to remove toxic substances from nitrogen metabolism of fishes. J Ichth, 23 (6): 159-161.
Kovatsis AB (1996) No metal inorganic poisons. In: Toxicology Data part A, Publication Service AU.Th.,: 186-190
Malestein A, Geurink JH, Schuyt G, Schotman AJH, Kemp A, van't Klooster ATh (1980) Nitrate poisoning in cattle 4. The effect of nitrite dosing during parturition on the oxygen capacity of maternal blood and the oxygen supply to the unborn calf. The Vet Quart, 2 (3): 149-159.
Maynard LA, Loosli JK (1969) The Inorganic Elements and Their Metabolism. In: Animal Nutrition. 6th ed. Me Graw-Hill Book Company: 223-225.
Merk (1998) Nitrate and nitrite poisoning. In: The Merk Veterinary Manual. 8th ed, Merk & CO INC., Whitehouse Station, N.J. U.S.A.,: 2091-2094
Mumpton FA (1984) Natural Zeolites. In: Zeo-Agriculture Use of Natural Zeolites in Agriculture and Aquaculture. Pond W.G., Mumpton F.A. (ed.), International Committee on Natural Zeolites Brockport, New York,: 33-44.
O' Hara Ρ J, Fraser AJ (1975) Nitrate poisoning in cattle grazing crops. New Ζ Vet J, 23 (4): 45-53.
Olson JR, Oehme FW, Carnahan DL (1972) Relationship of nitrate levels in water and livestock feeds to heard health problems on 25 Kansas farms. Vet Med Small Anim Clin, 67 (3): 257-260.
Osmen Ozlem, Mor Firdevs, Ayan Unsal (2003) Nitrate poisoning in cattle fed Chenopodium album hay. Vet Hum Toxic, 45 (2): 83-84.
Page RD, Gilson WD, Guthrie LD, Mertens DR, Hatch RC (1990) Serum progesterone and milk production and composition in dairy cows fed two concentrations of nitrate. Vet Hum Toxicol, 32 (1): 27-31.
Purcell DA, Raven AM, Thompson RH (1971) High nitrogen grass cubes as source of nitrite poisoning in cattle. Res Vet Sci, 12 (6):598-600.
Radostits OM, Blood DC, Gay CC (1994) Diseases caused by toxins in plants, fungi, cyanobacteria, clavibacteria, insects and animals. In: Veterinary Medicine, a Textbook of the Diseases of Cattle, Sheep, Pigs, Goats and Horses. 8th ed, Radostits O.M, Blood D.C., Gay C.C. (ed.), Bailliére Tindall London,: 1536-1539.
Rogers PAM, Hope-Cawdery MJ (1980) Monensin, ketosis and nitrate toxicity in cows. Vet Ree, 106: 311-312.
Slalina L, Slivka P, Struharicova J (1990) Transmammary transfer ofnitrates and nitrites in ruminants and methemoglobin blood levels in the young and their mothers. Veterinarni Medicina, 35(11): 647-656 (abstract).
Slenning BD, Galey FD, Anderson M (1991) Forage-related nitrate toxicoses possibly confounded by nonprotein nitrogen and monensin in the diet used at a commercial dairy heifer replacement operation. J Am Vet Med Assoc, 198 (5): 867-870.
Sokolowski JH, Hatfield EE, Garrigus US (1969) Effects of inorganic sulphur on potassium nitrate utilization by lambs. J Anim Sci, 28 (3): 391-396.
Soler Rodrigues F, Miguez Santiyin MP, Pedrera Zamorano JD (1992) Evaluation of reagent strips for the rapid diagnosis of nitrite poisoning. J Anal Toxic, 16 (1): 63-65.
Valli VEO, Parry BW (1993) The Haemopoietic System. In: Pathology of Domestic Animals Vol 3. 4th ed, Jubb K.V.F., Kennedy P.C., Palmer N. (ed.), Academic Press, San Diego-New York-Boston-London-Sydney-Tokyo-Toronto,: 208-209.
Winter AJ (1962) Studies on nitrate metabolism in cattle. Am J Vet Res, 23: 500-505.
Wood PA (1980) The molecular pathology of chronic nitrate intoxication in animals: a hypothesis. Vet Hum Toxicol, 22 (1):26-27.
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