A pre- and postpartum study of selected biochemical parameters in ewes for the early detection of pregnancy toxemia


N. ROUBIES (Ν. ΡΟΥΜΠΙΕΣ)
Z. S. POLIZOPOULOU (Ζ.Σ. ΠΟΛΥΖΟΠΟΥΛΟΥ)
A. MINAS (Α. ΜΗΝΑΣ)
A. PAPASTERIADIS (ΑΧ. ΠΑΠΑΣΤΕΡΙΑΔΗΣ)
Abstract

A field investigation on the incidence of subclinical ovine ketosis was performed in two large sheep flocks in an agricultural region of central Greece. Sixty - four animals were allocated in 2 study groups: group C, consisted of 29 non-pregnant females and group S of 35 end-term pregnant ewes. The trial lasted 6 weeks, including the immediate pre- and postpartal period. Blood samples were collected on weekly intervals and used for determining the concentrations of ß-hydroxybutyrate (BHB), acetoacetate (AcAc), glucose, total (TB) and conjugated (CB) bilirubin, calcium (Ca), inorganic phosphorus (P), sodium (Na), potassium (K), magnesium (Mg) and the activity of sorbitol dehydrogenase (SDH) and γ-glutamyl transferase (yGT). All the animals remained clinically healthy throughout the trial and parturition was uneventful. Eighteen group S ewes (51.4%) delivered 1 lamb, 12 (34,3%) twins, 4 (11.4%) triplets and 1 (2.9%) 4 lambs. Although the overall evaluation of the biochemical analysis did not support the existence of subclinical ketosis, blood glucose remained significantly lower (P<0.05) in group S sheep, with its lowest value (2.3±0.34 mmol/1) recorded 1 week prior to parturition. Sporadic cases of subclinical hyperketonemia may occur, despite optimal flock management.

Article Details
  • Rubrik
  • Research Articles
Downloads
Keine Nutzungsdaten vorhanden.
Literaturhinweise
Bauman DE and Currie WB. Partitioning of nutrients during pregnancy and lactation: A review of mechanisms involving homeostasis and homeothesis. J Dairy Sci, 1980, 63:1514-1529
Wastney WE, Wolff JE, and Bickerstaffe R. Glycose turnover and hepatocyte glucose production of starved and toxemic pregnant sheep. Aust J Biol Sci, 1983,36:271-284
Marteniuk JV and Herdt TH. Pregnancy toxemia and ketosis of ewes and does. Vet Clin North Am : Food An Pract, 1988,4(2):307-315
Andersson L. Subclinical ketosis in dairy cows. Vet Clin North Am: Food An Pract, 1988, 4(2): 233-251
Lean IJ, Brass ML, Baldwin RL, et al. Bovine ketosis: A review. I. Epidemiology and pathogenesis. Vet Bull, 1991, 61(12): 1209-1218
Rook JS. Pregnancy toxemia of ewes, does, and beef cows. Vet Clin North Am: Food An Pract, 2000,16(2): 293-317
Maine D. Role of nutrition in the prevention of toxemia. Am J Clin Nutr, 2000,72(1) Suppl: 298S-300S
Biyckhardt K, Neumann M and Steinmann C. Zur Bestimmung von Metabolism des Energiestoffwechsels in Leber-Biopsieproben-Ein Beitrag zur Charakterisierung der Schafketose. J Vet Med A, 1988,35: 790-799
Ford EJ, Evans J and Robinson I, Cortisol in pregnancy toxemia of sheep. Br Vet J, 1990,146:539-542
Kelly JM. Changes in serum B-hydroxybutyrate concentrations in dairy cows kept under commercial farm conditions. Vet Ree, 1977,101:499-502
Rossow N, Staufenbiel B, Staufenbiel R, et al. Zur Bewertung erhöhter Ketonkorperkonzutrationen bei der Milchkuh. Mh Vet Med, 1991,46:11-17
Wastney ME, Arcus AC, Bickerstaffe R, et al. Glucose tolerance in ewes and susceptibility to pregnancy toxemia. Aust. J Biol Sci, 1982,35:381-392
Lynch GP and Jackson C. A method for assessing the nutritional status of gestating ewes. Can J Anim Sci, 1983,63:603-611
Haraszti J. Die diagnostische und prognostische Bedeutung der Ketonurie bei den Fruchtbarkeitsstorungen des Rindes. Dtsch tierarztl Wschr, 1990,97:407-411
Mansion R, Rowlands GJ, Little W, et al. Variability of the blood composition of dairy cows in relation to time of day. J Agric Sci, 1981, 96:593-598
Bines JA and Morand SV. The effect of body condition on metabollic changes associated with intake of food by the cow. Br J Nutr, 1983,50:81-87
Kaneko JJ. Carbohydrate Metabolism and Its Diseases. In: Clinical Biochemistry of Domestic Animals, (JJ Kaneko, JW Harvey, ML Brass ed.). 5th ed, Academic Press, New York, 1997, 45-81.
Papasteriades A. Management of nutritional diseases of small ruminants in Greece. International seminar on the production and utilization of sheep and goat milk, Proceedings. Athens, 23-27 September 1985,173-230.
Bruss ML. Lipids and Ketones. In: Clinical Biochemistry of Domestic Animals, (JJ Kaneko, JW Harvey, ML Bruss ed.). 5th ed, Academic Press,New York, 1997, 83-115.
Herdt TH, Stevens JB, Olson WG, et al. Blood concentrations of â-hydroxybutyrate in clinically normal Holstein-Friesian herds and in those with a high prevalence of clinical ketosis. Am J Vet
Res, 1981,42:503-508
Baird GD. Primary ketosis in the high-producing dairy cow: clinical and subclinical disorders, treatment, prevention and outlook. J Dairy Sci, 1982, 65:1-9
The Perkin-Elmer Co: Analytical methods, 1977.
Boltz DF. Colorimetrie Determination of Nonmetals. Interscience Publishers Ine, 1958, 32-34
Gau Ν. Acetoacetic acid. In Methods in Clinical Chemistry (AJ Pesce and LA Kaplan eds) CV Mosby Co, 1987, 97-100
Gau Ν. B-hydroxybutyric acid. In: Methods in Clinical Chemistry (AJ Pesce and LA Kaplan eds) CV Mosby Co, 1987,101-104
Birckhardt K, Grocholl G and Konig G. Untersuchungen zum Glucosestoffwechsel von Schafen bei verschiedenen Reproduktionsstadien und bei Ketose mit Hilfe des intravenösen Glucose - Toleranz - Tests (IVGTT). J Vet Med A, 1989,36:514-529
Garcia Partida P, Prieto F and Benedito JL. Propartale Ketose beim Rind, ihre Behandlung mit Clanobutin. Tierarztl Umsch, 1988,43:641-646
Halse Κ, Hove Κ and Erkaas P. A biological definition of ketonemia in cows. Proceedings of the 5th International Conference on Production Disease in Farm Animals. Uppsala, 1983,137
Papasteriades A. Hypocalceamia in sheep under Greek conditions. Year Book of Veterinary School, AUTH, 1973,14:5-32.
Halse Κ and Velie W. Blood calcium in bovine ketosis. Am J Vet Res, 1977,19:575-579
Rayssiguier Y. Hypomagnesemia resulting from adrenaline infusion in ewes: its relation to lipolysis. Horm Metab Res, 1977, 9: 309-314
Grohn YT, Erb ΗΝ, McCullogh CE, et al. Epidemiology of metabolic disorders in dairy cattle: association among host characteristics, disease and production. J Dairy Sci, 1989, 72:1876-1885
Am häufigsten gelesenen Artikel dieser/dieses Autor/in