Modern aspects on etiopathogenesis of canine osteoarthritis

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Опубликован: Nov 27, 2017
DOI: https://doi.org/10.12681/jhvms.15006
A. M DANOURDIS (Α. Μ. ΔΑΝΟΥΡΔΗΣ)
Private Practitioner
A. F. KOUTINAS (Α.Φ. ΚΟΥΤΙΝΑΣ)
Clinic of Companion Animal Medicine, School of Veterinary Medicine, Aristotle University of Thessaloniki
Аннотация

Extracellular matrix and chondrocytes are the main structure components of the articular cartilage. The extracellular matrix is largely comprised of collagen fibers, proteoglycans and water, whereas the metabolically active chondrocytes are responsible for its production and maintenance. An interaction of the physical and biochemical characteristics of the articular cartilage is necessary for normal joint function by providing nearly frictionless motion, wear resistance, joint congruence and loading transmission to subchondral bone. The vicious cycle of osteoarthritis sets forth when structural and homeostatic aberrations, secondary to congenital or acquired joint diseases, occur in the articular cartilage. Although the pathological and biochemical changes of the articular cartilage in the osteoarthritic joint have been studied extensively, the exact mechanism pertaining its pathogenesis is still unknown.

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Библиографические ссылки
Akizuki et al (1987) Tensile properties of human knee cartilage II. Correlation between weight bearing and tissue pathology and the kinetics of swelling. J Orthop Res 5:173-175
Allan G S (2000) Radiographic features of feline joint disease Vet clin North Am Small Anim Pract 30:281-285
Aydelotte MB, Kuettner KE (1993) Heterogeneity of articular chondrocytes and cartilage matrix. In : Woessner JF, Howell DS (eds) Joint cartilage degradation. New York , Marcel Dekker, :37-40
Buckland WC (1997) Current status of imaging procedures in the diagnosis, prognosis and monitoring of osteoarthritis Bailliere's Clin Rheumatol 11: 727-748
Buckwalter JA, Mankin HJ (1998) Articular cartilage : Tissue design and chondrocyte - matrix interactions. Instr Course Lect 47:477-479
Buckwalter JA (1995) Articular cartilage repair and transplantation Arthritis Rheum 41: 1331-1334
Burr DB, Radin EL (1990) Trauma as a factor in the initiation of osteoarthritis. In: Brand KD (ed) Cartilage change in osteoarthritis. Indianapolis, Indiana University School of Medicine: 63-69
Γαλανόπουλος ΝΓ (1999) Βασική Κλινική Ρευματολογία. Ιατρικές Εκδόσεις ΠΧ Πασχαλίδης, Αθήνα: 177-191
Dean DD, Martel PJ, Pelletier JP, Howell DS, Woessner JF (1989) Evidence for metalloproteinase and metalloproteinase inhibitor imbalance in human osteoarthritis cartilage . J Clin Invest 84 :
-685
Ferreira SH (1972) Prostaglandins, aspirin-like drugs and analgesia. Nature 240:200-210
Gilbertson EM (1975) Development of periarticular osteophytes in experimentally induced osteoarthritis in the dog. Ann Rheum Dis 34:12-16
Goldring MB (1999) The role of cytokines as inflammatory mediators in osteoarthritis: lessons from animal models. Connect Tissue Res 40: 1-11
Ζαφειρόπουλος ΓΘ (1997) Εμβιομηχανική του μυοσκελετικού συστήματος. Εκδόσεις Γρηγόριος Παρισιάνος Αθήνα:32-34
Johnston SA (1997) Osteoarthritis: Joint anatomy, physiology and pathobiology. Vet clin North Am Small Anim Pract 27:698-722
Κουτίνας ΑΦ, Πολυζωποΰλου ΖΣ, Δανοΰρδης AM. (2003) Κλινική Νευρολογία, Αρθροπαθολογία και Οστεοπαθολογία του Σκύλου και της Γάτας, Εκδόσεις Σύγχρονη Παιδεία, Θεσσαλονίκη:229-231
Korn JH (1997) Pathogenesis of osteoarthritis In: Kelly WN, et al (eds) Textbook of Rheumatology, vol 1, 5th ed. WB Sauders, Philadelphia: 199-205
Lepine AL (2000) A morphologic and physiologic review of articular cartilage. In Proceeding from a Symposium (Articular cartilage and joint health. IAMS Company) March 7, 2000, France: 12-14
Lotz M (1997) Cytokines and their receptors. In : Koopman WJ (ed) Artritis and allied conditions, ed 13. Baltimore, Williams & Wilkins: 439-441
Μιχαήλ Σ.Γ (1995) Συγκριτική ανατομική των κατοικίδιων θηλαστικών. Θεσσαλονίκη: 192-193
Mankin Η J (1986) Workshop on etiopathogenesis of osteoarthritis. Proceedings and recommendations. J Rheumatol 13:1127-1128
Mankin HJ, Brandt KD (1997) Pathogenesis of osteoarthritis In : Kelly WN, et al (eds) Textbook of Rheumatology, vol 1, 5th ed. WB Sauders, Philadelphia: 1369-1350
Mayne R (1997) Structure and function of collagen. In: Koopman WJ (ed) Artritis and allied conditions, ed 13. Baltimore, Williams & Wilkins:1969-1975
Moskowits RW, Golberg VM (1987) Studies of osteophyte pathogenesis in experimentally induced osteoarthritis J Rheumatol 14: 311-312
Mow VC, Roth V and Armstrong CG (1980) Biomechanics of joint cartilage. In: Frankel VH, Mordin M (eds). Basic Biomechanics of the Skeletal System. Philadelphia: Lea & Febiger: 61-86
Niethard FU (1999) Pathogenesis of osteoarthritis - approaches to specific therapy. American Journal of Orthopedics 28: 8-10
Oloyende A, Flachsmann R (1992) The dramatic influence of loading velocity on the compressive response of articular cartilage. Connect Tissue Res 27:211-213
Pelletier JP, McCollum R, Cloutier JM (1995) Synthesis of metaloproteinases and interleukin 6 in human osteoarthritic synovial membrane is an IL-1 mediated process J Rheumatol 22:109-115
Perrinof S, Foster JA 1997 Developmental regulation of elastin gene expression. Crit Rev Eukaryot Gene Expr 7:1-10
Poole CA (1993) The structure and function of articular cartilage matrices. In: Woessner JF, Howell DS (eds) Joint cartilage degradation. New York, Marcel Dekker:l-5
Pritzker KPH (1998) Pathology of osteoarthritis In : Brand KD, Doberty M, Lobmander S (ed) Osteoarthritis New York Oxford University Press: 50-61
Sandy JD, Plaas AHK (1997) Structure, function and metabolism of cartilage proteoglycans. In: Koopman WJ (ed) Arthritis and allied conditions, ed 13. Baltimore, Williams & Wilkins: 225- 229
Simkin PA, Bassett JA (1995) Cartilage matrix molecules in serum and synovial fluid Curr Opin Rheumatol 7: 346-351
Simkin PA (1997) Synovial physiology In: Koopman WJ (ed) Artritis and allied conditions, ed 13. Baltimore, Williams & Wilkins: 193-210
Simon SR, Radin EL (1997) Biomechanics of joints. In : Kelly WN, et al (eds): Textbook of Rheumatology, vol 1, 5th ed. WB Sauders, Philadelphia: 86-89
Stockwell RA (1979) Biology of Cartilage Cells, vol 7. London, Cambridge University Press
Todhunder RJ. (1992) Synovial joint anatomy , biology and pathobiology. In Auer J, (ed) Equine surgery W Β Sauders Philadelphia: 844-865
Todhunder RJ (1998) Composition of Labrador retriever chondroepiphyses. Annual Meeting American College of Veterinary Surgeons, Chicago
Todhunter RJ, Johnston SA (2003) Osteoarthritis. In: Slatter (ed) Textbook of Small Animal Surgery, 3rd ed. WB Saunders, Philadelphia: 2221 – 2224
Urban JP (1994) The chondrocyte: a cell under pressure. Br J Rheumatol 33: 269-272
Van der Kraam PM, Van der Berg WB (2000) Anabolic and destructive mediators in osteoarthritis. Curr Opi Clin Nutr Metab Care 3: 205-211
Walter CR (2005) Pathophysiology and management of arthritis. Vet clin North Am Small Anim Pract 35:1073-1091
Zimmermann M (1989) Pain mechanism and mediators in osteoarthritis. Seminar Arthritis Rheum 18:22-29
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